Building global research equity through lung organoids: a prerequisite for the next respiratory pandemic [PDF]
Frontiers in MedicineMuhammad Kamal Hossain +4 more
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Disease modeling and drug screening using human airway organoids: a systematic review [PDF]
Organoid, 2021 Increasing levels of fine environmental dust particles due to industrialization and emerging respiratory illnesses, such as coronavirus disease 2019, pose serious threats to human life.
Do Hyun Kim, Sung Won Kim
doaj +1 more source
Engineered models for studying blood-brain-barrier-associated brain physiology and pathology [PDF]
Organoid, 2021 The blood-brain barrier (BBB) is a transport barrier that suppresses the translocation of potentially harmful substances to the brain tissue. Although the BBB is known to be associated with many kinds of neuropathology, such as neuroinflammation and ...
Hong Nam Kim
doaj +1 more source
A novel method for the isolation of CD45-positive and CD45-negative cells from malignant pleural effusion [PDF]
Organoid, 2021 Background Patient-derived malignant pleural effusion (MPE) samples can be used to identify a patient-specific drug combination since MPE samples are readily available and cost-effective tumor cell sources.
Jimin Choi +5 more
doaj +1 more source
Strategies for vascularization in kidney organoids [PDF]
Organoid, 2022 The establishment of protocols for differentiating kidney organoids from human pluripotent stem cells (hPSCs) has potential for the application of kidney organoids in regenerative medicine. However, the primary obstacle to the regenerative application of
Seo-Yeon Park, Yong Kyun Kim
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Rapid anticancer drug screening using patient-derived lung cancer organoids: a case report [PDF]
Organoid, 2022 A variety of anticancer drugs and targeted agents for lung cancer have been developed, but some patients do not respond to these medications as intended.
Hyeong Jun Cho +6 more
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Journal of Orthopaedic Translation, 2022 Background: Bone fracture healing is a postnatal regenerative process in which fibrocartilaginous callus formation and bony callus formation are important. Bony callus formation requires osteoblastic differentiation of MSCs.
Fuxiao Wang +9 more
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Technical advances in pluripotent stem cell-derived and tumorigenic organoids [PDF]
Organoid, 2022 Cell culture systems have been widely used to address fundamental questions in biology without sacrificing animals. Three-dimensional (3D) organoids provide more information on in vivo conditions than traditional culture systems because multiple cell ...
Suwon Kang +3 more
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Whole Organ Engineering: Approaches, Challenges, and Future Directions
Applied Sciences, 2020 End-stage organ failure remains a leading cause of morbidity and mortality across the globe. The only curative treatment option currently available for patients diagnosed with end-stage organ failure is organ transplantation.
Sogu Sohn +4 more
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A method for culturing patient-derived lung cancer organoids from surgically resected tissues and biopsy samples [PDF]
Organoid, 2022 Background The cancer model system maintaining genetic and phenotypic characteristics of human cancers is crucial for the study of precision cancer medicine.
Yu Ri Ko +4 more
doaj +1 more source