Results 21 to 30 of about 5,723 (210)
Molecular Autism, 2020 The complex pathophysiology of autism spectrum disorder encompasses interactions between genetic and environmental factors. On the one hand, hundreds of genes, converging at the functional level on selective biological domains such as epigenetic ...
Cristina Cheroni +2 more
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ChatGPT: The cognitive effects on learning and memory
Brain-X, 2023 As the integration of artificial intelligence (AI) into our daily lives and educational environments becomes increasingly prevalent, it is necessary to understand the way in which these technologies impact cognitive functions.
Long Bai, Xiangfei Liu, Jiacan Su
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Single organoid RNA-sequencing reveals high organoid-to-organoid variability [PDF]
, 2021 ABSTRACT Over the last decades, organoids have been established from the majority of tissue resident stem and iPS cells. They hold great promise for our understanding of mammalian organ development, but also for the study of disease or even personalized medicine.
Kristin Gehling +6 more
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Medecine sciences : M/S, 2020 As burden of chronic respiratory diseases is constantly increasing, improving in vitro lung models is essential in order to reproduce as closely as possible the complex pulmonary architecture, responsible for oxygen uptake and carbon dioxide clearance. The study of diseases that affect the respiratory system has benefited from in vitro reconstructions ...
Bourguignon, Chloé +10 more
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BMC Urology, 2023 Background In intermediate-risk non-muscle invasive bladder cancer (NMIBC) clinical guidelines suggest an adjuvant instillation with a chemotherapeutic agent. However, the agent and regimen are not clearly defined.
Roland Seiler +10 more
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Science, 2019 Recent studies have demonstrated an array of stem cell–derived, self-organizing miniature organs, termed organoids, that replicate the key structural and functional characteristics of their in vivo counterparts. As organoid technology opens up new frontiers of research in biomedicine, there is an emerging need for innovative engineering approaches for ...
Sunghee Estelle Park +2 more
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Lung organoids: target cells for understanding respiratory diseases [PDF]
Organoid, 2021 Human respiratory disease research currently lacks in vitro models that recapitulate most of the physiology and architecture of the lung. Furthermore, the complex composition and structure of the lung, as well as anatomical differences between humans and
Jooyeon Lee, Se-Ran Yang
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Emerging organoid-based platforms to study salivary gland hypofunction [PDF]
Organoid, 2022 Xerostomia is a pathologic condition of hyposalivation due to salivary gland (SG) dysfunction. Although xerostomia significantly affects the quality of patients’ life, there is no satisfactory treatment for this disease.
Yoojin Seo, Hyung-Sik Kim
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Recent advances in liver organoids and their use in modeling of non-alcoholic fatty liver disease [PDF]
Organoid, 2022 The liver is involved in physiological activities critical for survival. Chronic liver disease (CLD) frequently progresses to life-threatening liver failure, as evidenced by CLD patients’ high morbidity and mortality rates.
Kyun Yoo Chi, Jong-Hoon Kim
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Fundamental signaling pathways for glioblastoma drug resistance and developing robust organoid models for drug discovery [PDF]
Organoid, 2022 This article presents a review of the current literature on the molecular mechanisms of treatment resistance in glioblastoma. As mounting research continues to explore novel methods of treating glioblastoma, from using organoid models for drug screening ...
Athira Pratap +3 more
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