Results 21 to 30 of about 90,274 (350)
Molecular Autism, 2020 The complex pathophysiology of autism spectrum disorder encompasses interactions between genetic and environmental factors. On the one hand, hundreds of genes, converging at the functional level on selective biological domains such as epigenetic ...
Cristina Cheroni +2 more
doaj +1 more source
Inkjet-based bioprinting for tissue engineering [PDF]
Organoid, 2023 Inkjet bioprinting, a derivative of traditional inkjet technology, is gaining recognition in the fields of life sciences and tissue engineering due to its ability to produce picoliter volume droplets at high speeds in a non-contact fashion.
Ju An Park, Yunji Lee, Sungjune Jung
doaj +1 more source
A 3-D in vitro co-culture model of mammary gland involution. [PDF]
, 2014 Involution is a process whereby the mammary gland undergoes extensive tissue remodelling involving exquisitely coordinated cell death, extracellular matrix degradation and adipose tissue regeneration following the weaning of offspring.
Botos, Laur-Alexandru +5 more
core +3 more sources
Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition [PDF]
, 2016 EZH2 inhibitors have gained great interest for their use as anti-cancer therapeutics. However, most research has focused on EZH2 mutant cancers and recently adverse effects of EZH2 inactivation have come to light.
Bounova, Gergana +6 more
core +1 more source
ChatGPT: The cognitive effects on learning and memory
Brain-X, 2023 As the integration of artificial intelligence (AI) into our daily lives and educational environments becomes increasingly prevalent, it is necessary to understand the way in which these technologies impact cognitive functions.
Long Bai, Xiangfei Liu, Jiacan Su
doaj +1 more source
Bioengineering, 2023 Tissue organoids hold enormous potential as tools for a variety of applications, including disease modeling and drug screening. To effectively mimic the native tissue environment, it is critical to integrate a microvasculature with the parenchyma and stroma. In addition to providing a means to physiologically perfuse the organoids, the microvasculature
Hannah A. Strobel +2 more
openaire +3 more sources
BMC Urology, 2023 Background In intermediate-risk non-muscle invasive bladder cancer (NMIBC) clinical guidelines suggest an adjuvant instillation with a chemotherapeutic agent. However, the agent and regimen are not clearly defined.
Roland Seiler +10 more
doaj +1 more source
Rapid anticancer drug screening using patient-derived lung cancer organoids: a case report [PDF]
Organoid, 2022 A variety of anticancer drugs and targeted agents for lung cancer have been developed, but some patients do not respond to these medications as intended.
Hyeong Jun Cho +6 more
doaj +1 more source
Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. [PDF]
, 2018 Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches.
Castillo-Azofeifa, David +7 more
core +1 more source
Organoid assessment technologies
Clinical and Translational Medicine, 2023 AbstractDespite enormous advances in the generation of organoids, robust and stable protocols of organoids are still a major challenge to researchers. Research for assessing structures of organoids and the evaluations of their functions on in vitro or in vivo is often limited by precision strategies. A growing interest in assessing organoids has arisen,
Yuyuan Gu +5 more
openaire +3 more sources