Decoupling Growth and Production by Removing the Origin of Replication from a Bacterial Chromosome. [PDF]
ACS Synth Biol, 2022 Kasari M, Kasari V, Kärmas M, Jõers A.
europepmc +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes [PDF]
, 2003 The presence of a genetic component in longevity is well known. Here, the association of a mtDNA mutation with a prolonged life span in humans was investigated.
Asin-Cayuela, Jordi +9 more
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DNA Replication Origins and Fork Progression at Mammalian Telomeres [PDF]
, 2017 Mitsunori Higa +2 more
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A Method to Generate and Rescue Recombinant Adenovirus Devoid of Replication-Competent Particles in Animal-Origin-Free Culture Medium [PDF]
, 2023 Seyyed Mehdy Elahi +3 more
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Thymine starvation causes abortive initiation of chromosome replication critical for cell death in Escherichia coli [PDF]
, 2013 Presentado en: XXXVI Congreso SEBBM (Sociedad Española de Bioquímica y Biología Molecular), Madrid, 4-6 septiembre, 2013Thymineless death (TLD), a phenomenon in which thymine auxotrophy becomes lethal when cells are starved for thymine, can be prevented
Guzmán Cabañas, Elena +2 more
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Fine mapping of replication origins (oriA and oriB) in Nicotiana tabacum chloroplast DNA [PDF]
, 1997 Muthusamy Kunnimalaiyaan +1 more
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Plasmid replication based on the T7 origin of replication requires a T7 RNAP variant and inactivation of ribonuclease H. [PDF]
Nucleic Acids Res, 2021 Becker K, Meyer A, Roberts TM, Panke S.
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Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source