Results 141 to 150 of about 24,134 (239)

Key regulator of cellular metabolism, estrogen-related receptor α, a new therapeutic target in endocrine-related gynecological tumor

Cancer Management and Research, 2018
GuiFen Liu,1 PengMing Sun,1,2 BinHua Dong,1 Jalid Sehouli3 1Laboratory of Gynaecologic Oncology, Fujian Provincial Maternity and Children’s Hospital, Affiliated Hospital of Fujian Medical University, 350001 Fuzhou, Fujian, People’s Republic ...
Liu G, Sun P, Dong B, Sehouli J
doaj  

Retraction Note: Distinct Repressive Properties of the Mammalian and Fish Orphan Nuclear Receptors SHP and DAX-1. [PDF]

Mol Cells, 2018
Park YY, Teyssier C, Vanacker JM, Choi HS.   +3 more
europepmc   +1 more source

Phosphorylation disrupts the interaction between the intrinsically disordered region of the oncogenic NDRG1 and lipid vesicles

Protein Science, Volume 35, Issue 3, March 2026.
Abstract NDRG1 is a multifunctional regulatory human protein implicated in crucial cellular processes and acting as a central hub of a cancer‐related interactome. In lung cancer, increased NDRG1 expression is associated with resistance to chemotherapy and is linked to the cellular response to nickel, a known tumor driver in air pollution.
Noemi Carosella, Chiara Pastorello, Jehan Waeytens, Ylenia Beniamino, Valentina Roncassaglia, Lucrezia Serra, Vincent Raussens, Elisabetta Mileo, Stefano Ciurli, Barbara Zambelli   +9 more
wiley   +1 more source

The orphan nuclear receptors at their 25-year reunion. [PDF]

J Mol Endocrinol, 2013
Mullican SE, Dispirito JR, Lazar MA.
europepmc   +1 more source

Orphan Nuclear Receptors: The Exotics of Xenobiotics [PDF]

Journal of Biological Chemistry, 2001
W, Xie, R M, Evans
openaire   +2 more sources

Unraveling the Link Between Azathioprine and Acute Pancreatitis: Integrating Network Toxicology, Machine Learning, and Mendelian Randomization

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Azathioprine (AZA), a widely used immunosuppressant, can induce acute pancreatitis (AP), yet the underlying molecular mechanisms remain unclear. This study employed an integrative multiomics strategy—combining network toxicology, machine learning, Mendelian randomization (MR), and molecular docking—to elucidate the biological basis of AZA ...
Zhijun Xie, Hang Lei, Pengcheng Zhang, Zhi Li, Wenfu Tang   +4 more
wiley   +1 more source

Lipid-sensors, enigmatic-orphan and orphan nuclear receptors as therapeutic targets in breast-cancer. [PDF]

Oncotarget, 2016
Garattini E, Bolis M, Gianni' M, Paroni G, Fratelli M, Terao M.   +5 more
europepmc   +1 more source

Nuclear Orphan Receptor [PDF]

, 2020
openaire   +1 more source

Additional file of Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes

, 2021
Henriette O’Geen, Yu-Hsuan Lin, Xiaoqin Xu, Lorigail Echipare, Vitalina Komashko, Daniel He, Seth Frietze, Osamu Tanabe, Lihong Shi, Maureen A. Sartor, James Douglas Engel, Peggy Farnham   +11 more
openalex   +1 more source

A survey of downstream applications of evolutionary scale modeling protein language models

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The evolutionary scale modeling (ESM) series is promising to revolutionize protein science and engineering through large language models (LLMs), providing a robust framework for understanding the relationships among sequences, structures, and functions of proteins.
Qingyu Yang, Jiale Yu, Jie Zheng
wiley   +1 more source