Results 11 to 20 of about 7,142 (165)

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics. [PDF]

MedComm (2020)
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yan Y, Sun Y, Sun G, Niu C, Zhao X, Zhao M, Liu T, Zhang S, Zhai H, Liu A, Yu S, Pan S, Zhong W, Zhang Y, Li S.   +14 more
europepmc   +2 more sources

Evolution of the orthopoxvirus core genome

Virus Research, 2023
Orthopoxviruses comprise several relevant pathogens, including the causative agent of smallpox and monkeypox virus. Analysis of orthopoxvirus genome evolution mainly focused on gene gains/losses. We instead analyzed core genes, which are conserved in all orthopoxviruses.
Molteni, Cristian, Forni, Diego, Cagliani, Rachele, Mozzi, Alessandra, Clerici, Mario, Sironi, Manuela   +5 more
openaire   +4 more sources

Global health emergency of monkeypox after COVID-19: A narrative review

Journal of Surgical Specialties and Rural Practice, 2022
Global hit by coronavirus is followed by another public health emergency known as monkeypox (MPX) that is a rare disease and yet has presented with sudden and wide geographic distribution.
Prachi Jain, Manu Rathee, Akanksha Gopal Shetye, S Rajesh Divakar, Sandeep Singh, Sarthak Singh Tomar   +5 more
doaj   +1 more source

Vaccinia Virus Infection in Monkeys, Brazilian Amazon

Emerging Infectious Diseases, 2010
To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples.
Jônatas S. Abrahão, André T. Silva-Fernandes, Larissa S. Lima, Rafael K. Campos, Maria I.M.C. Guedes, Marcela M.G. Cota, Felipe L. Assis, Iara A. Borges, Milton F. Souza-Júnior, Zélia I.P. Lobato, Cláudio A. Bonjardim, Paulo C.P. Ferreira, Giliane S. Trindade, Erna G.   +13 more
doaj   +1 more source

Epidemiologic and Ecologic Investigations of Monkeypox, Likouala Department, Republic of the Congo, 2017

Emerging Infectious Diseases, 2019
Monkeypox, caused by a zoonotic orthopoxvirus, is endemic in Central and West Africa. Monkeypox has been sporadically reported in the Republic of the Congo. During March 22–April 5, 2017, we investigated 43 suspected human monkeypox cases. We interviewed
Reena H. Doshi, Sarah Anne J. Guagliardo, Jeffrey B. Doty, Angelie Dzabatou Babeaux, Audrey Matheny, Jillybeth Burgado, Michael B. Townsend, Clint N. Morgan, Panayampalli Subbian Satheshkumar, Nestor Ndakala, Therese Kanjingankolo, Lambert Kitembo, Jean Malekani, Lem’s Kalemba, Elisabeth Pukuta, Tobi N’kaya, Fabien Kangoula, Cynthia Moses, Andrea M. McCollum, Mary G. Reynolds, Jean-Vivien Mombouli, Yoshinori Nakazawa, Brett W. Petersen   +22 more
doaj   +1 more source

Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus

Emerging Microbes and Infections, 2023
The worldwide outbreak of the monkeypox virus (MPXV) has become a “Public Health Emergency of International Concern” (PHEIC). Severe monkeypox virus infection can be fatal, however, effective therapeutic methods are yet to be developed.
Mengjun Li, Zuning Ren, Yuelin Wang, Yushan Jiang, Minghui Yang, Delin Li, Jiayin Chen, Zuxin Liang, Yuhao Lin, Zhujun Zeng, Rui Xu, Yiting Wang, Li Zhu, Weiwei Xiao, Qinghua Wu, Bao Zhang, Chengsong Wan, Yang Yang, Bo Wu, Jie Peng, Wei Zhao, Chenguang Shen   +21 more
doaj   +1 more source

Animal infections by vaccinia-like viruses in the state of Rio de Janeiro: an expanding disease Infecções animais por vírus semelhantes ao vaccínia no estado do Rio de Janeiro: uma doença em expansão

Pesquisa Veterinária Brasileira, 2009
In the present study we investigated the presence of infections by vaccinia-like viruses in dairy cattle from 12 counties in the state of Rio de Janeiro in the last 9 years.
Hermann G. Schatzmayr, Bruno R. Simonetti, Danielle C. Abreu, José P. Simonetti, Sandra R. Simonetti, Renata V.C. Costa, Márcia Cristina R. Gonçalves, Paulo Sérgio D'Andréa, Marconny Gerhardt, Manuel E. Vieira Silva, José C. Farias-Filho, Ortrud M. Barth   +11 more
doaj   +1 more source

Mapping the Landscape of Health Research Priorities for Effective Pandemic Preparedness in Human Mpox Virus Disease

Pathogens, 2023
The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has highlighted the critical importance of timely virus detection and robust public health surveillance in assessing outbreaks and their impact.
Sumit Aggarwal, Pragati Agarwal, Kuldeep Nigam, Neetu Vijay, Pragya Yadav, Nivedita Gupta   +5 more
doaj   +1 more source

Orthopoxvirus Seroprevalence and Infection Susceptibility in France, Bolivia, Laos, and Mali

Emerging Infectious Diseases, 2022
To determine a demographic overview of orthopoxvirus seroprevalence, we tested blood samples collected during 2003–2019 from France (n = 4,876), Bolivia (n = 601), Laos (n = 657), and Mali (n = 255) for neutralizing antibodies against vaccinia virus. In
Léa Luciani, Nathanaël Lapidus, Abdennour Amroun, Alessandra Falchi, Chanthala Souksakhone, Mayfong Mayxay, Audrey Dubot-Pérès, Paola Mariela Saba Villarroel, Issa Diarra, Ousmane Koita, Pierre Gallian, Xavier de Lamballerie   +11 more
doaj   +1 more source

Orthopoxvirus Infections in Rodents, Nigeria, 2018–2019

Emerging Infectious Diseases, 2023
To investigate animal reservoirs of monkeypox virus in Nigeria, we sampled 240 rodents during 2018-2019. Molecular (real-time PCR) and serologic (IgM) evidence indicated orthopoxvirus infections, but presence of monkeypox virus was not confirmed.
Clement Meseko, Adeyinka Adedeji, Ismaila Shittu, Emmanuel Obishakin, Maurice Nanven, Ladan Suleiman, Daniel Okomah, Visa Tyakaray, Damilola Kolade, Adesola Yinka-Ogunleye, Saleh Muhammad, Clint N. Morgan, Audrey Matheny, Yoshinori Nakazawa, Andrea McCollum, Jeffrey B. Doty   +15 more
openaire   +3 more sources