Results 71 to 80 of about 11,507 (279)
Serological Evidence of Orthopoxvirus Infection in Neotropical Primates in Brazil
Pathogens, 2022 The genus Orthopoxvirus (OPXV) of the family Poxviridae comprises several viruses that are capable of infecting a wide range of hosts. One of the most widespread OPXVs is the Vaccinia virus (VACV), which circulates in zoonotic cycles in South America ...
Filipe V. S. Abreu +24 more
semanticscholar +1 more source
Targeting of IL-2 to cytotoxic lymphocytes as an improved method of cytokine-driven immunotherapy [PDF]
, 2017 The use of high-dose interleukin-2 (IL-2) has fallen out of favor due to severe life-threatening side effects. We have recently described a unique way of directly targeting IL-2 to cytotoxic lymphocytes using a virally encoded immune evasion protein and ...
Fremont, Daved H +6 more
core +2 more sources
Orthopoxvirus infection transmitted by a domestic cat
Journal of the American Academy of Dermatology, 2006 The variola virus was declared eradicated by the World Health Organization in 1980 but human infections by cowpox virus, another member of the genus Orthopoxvirus, are still observed, mainly in European countries. We report a woman who presented with two umbilicated vesicles surrounded by an indurated erythematous edema within cat scratch injuries on ...
Haenssle, Holger Andreas +5 more
openaire +4 more sources
Apparition de lésions proches de la variole bovine chez des bovins en Israël
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996 Les auteurs décrivent deux formes cliniques différentes de variole bovine apparues sporadiquement dans un troupeau laitier et dans un troupeau à viande.
I. Yeruham +3 more
doaj +1 more source
Microbiology Spectrum, 2022 Monkeypox virus (MPXV) is a human pathogenic virus that belongs to the genus Orthopoxvirus. In 2022, MPXV caused an unprecedented number of infections in many countries.
Junxia Feng +18 more
doaj +1 more source
Journal of Virology, 2021 The eradication of smallpox and subsequent cessation of vaccination have left a majority of the population susceptible to variola virus or other emerging poxviruses. This is exemplified by human monkeypox, as evidenced by the increase in reported endemic
E. Mucker +8 more
semanticscholar +1 more source
Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]
, 2008 Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Baranowski, Eric +4 more
core +1 more source
Orthopoxvirus Targets for the Development of Antiviral Therapies [PDF]
Current Drug Target -Infectious Disorders, 2005 The potential use of smallpox virus as a bioterror agent and the endemic presence of monkeypox virus in Africa underscores the need for better therapies for orthopoxvirus infections. The only existing clinical experience treating vaccinia and smallpox infections has been with Marboran, which suggested that antiviral therapies could be effective in ...
Earl R. Kern, Mark N. Prichard
openaire +3 more sources
Monkeypox: An alarming global health emergency
APIK Journal of Internal Medicine, 2022 Monkeypox (MPX) virus is an orthopoxvirus that causes human MPX, a viral disease with symptoms indistinguishable to smallpox, which includes fever and rash.
Vasantha Kamath +2 more
doaj +1 more source
An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications
Expert Review of Anti-Infective Therapy, 2020 Introduction Tecovirimat (TPOXX®; ST-246) was approved for the treatment of symptomatic smallpox by the USFDA in July of 2018 and has been stockpiled by the US government for use in a smallpox outbreak.
Andrew T. Russo +8 more
semanticscholar +1 more source