Results 71 to 80 of about 11,628 (248)

Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication. [PDF]

, 2013
Myxoma virus (MYXV)-encoded protein M029 is a member of the poxvirus E3 family of dsRNA-binding proteins that antagonize the cellular interferon signaling pathways.
Chan, Winnie M, Liu, Jia, McFadden, Grant, Rahman, Masmudur M, Rothenburg, Stefan   +4 more
core   +1 more source

A Pyrido‐Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Erika Plicanti, Andrea Deiana, Silvia Nottoli, Giulia Lottini, Roberta Ibba, Sandra Piras, Carlo Di Marzo, Silvia Vegni, Michele Lai, Mauro Pistello, Antonio Carta, Giulia Freer   +11 more
wiley   +1 more source

Effect of Monkeypox Virus Preparation on the Lethality of the Intravenous Cynomolgus Macaque Model

Viruses, 2022
For over two decades, researchers have sought to improve smallpox vaccines and also develop therapies to ensure protection against smallpox or smallpox-like disease.
Eric M. Mucker, Josh D. Shamblin, Jo Lynne Raymond, Nancy A. Twenhafel, Robert F. Garry, Lisa E. Hensley   +5 more
doaj   +1 more source

Exceptional Clinical Resistance and Variable Reservoir Competence [PDF]

, 2018
Cowpox virus (CPXV) is a zoonotic virus and endemic in wild rodent populations in Eurasia. Serological surveys in Europe have reported high prevalence in different vole and mouse species.
Beer, Martin, Franke, Annika, Hoffmann, Donata, Keller, Markus, Osterrieder, Nikolaus, Ulrich, Rainer G., Weber, Saskia   +6 more
core   +1 more source

Diagnostic electron microscopy in human infectious diseases – Methods and applications

Journal of Microscopy, Volume 299, Issue 3, Page 186-205, September 2025.
Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley   +1 more source

Serologic evidence of human orthopoxvirus infections in Sierra Leone

BMC Research Notes, 2011
Background Orthopoxviruses, including variola virus, vaccinia virus, and monkeypox virus, have previously been documented in humans in West Africa, however, no cases of human orthopoxvirus infection have been reported in the region since 1986.
Goba Augustine, Lungay Victor K, Robert Willie, Kanneh Lansana D, Fonnie Richard, Lash RR, Reynolds Mary G, Abel Jason, MacNeil Adam, Moses Lina M, Damon Inger K, Karem Kevin, Bausch Daniel G   +12 more
doaj   +1 more source

Microparasites and their potential impact on the population dynamics of small cetaceans from South America: a brief review. Document SC/59/DW8, Scientific Committee, International Whaling Commission, Anchorage, Alaska, 4-14 May 2007 [PDF]

, 2007
We briefly review the pathology, epidemiology and molecular biology of cetacean viruses (including morbilli, papilloma and pox) and Brucella spp. encountered in South America.
Barrett, T., Crespo, E., Di Beneditto, A.P., Raga, J.A., Siciliano, S., Van Bressem, M.-F., Van Waerebeek, K.   +6 more
core  

Desenvolvimento de software para a detecção de grupos de genes homólogos sob evidência de seleção positiva. [PDF]

, 2020
O presente trabalho descreve o desenvolvimento de um software para a busca por grupos de genes homólogos sob evidência de seleção positiva. Nesse trabalho, desenvolveu-se um software em perl para integrar diversos softwares de terceiros capazes de ...
HONGO, J. A., LOBO, F. P.
core  

MyD88-Dependent Immunity to a Natural Model of Vaccinia Virus Infection Does Not Involve Toll-Like Receptor 2. [PDF]

, 2014
UNLABELLED: Although the pattern recognition receptor Toll-like receptor 2 (TLR2) is typically thought to recognize bacterial components, it has been described to alter the induction of both innate and adaptive immunity to a number of viruses, including ...
Davies, Michael L, Eisenlohr, Laurence C., Norbury, Christopher C, Roscoe, Felicia, Sei, Janet J, Siciliano, Nicholas A, Sigal, Luis J, Xu, Ren-Huan   +7 more
core   +2 more sources

Orthopoxvirus infection transmitted by a domestic cat

Journal of the American Academy of Dermatology, 2006
The variola virus was declared eradicated by the World Health Organization in 1980 but human infections by cowpox virus, another member of the genus Orthopoxvirus, are still observed, mainly in European countries. We report a woman who presented with two umbilicated vesicles surrounded by an indurated erythematous edema within cat scratch injuries on ...
Haenssle, Holger Andreas, Kiessling, J., Kempf, Volkhard A. J., Fuchs, Tina, Neumann, C., Emmert, Steffen   +5 more
openaire   +3 more sources