Results 71 to 80 of about 13,277 (283)

La variole du dromadaire chez le jeune au Maroc. Isolement et identification du virus. Mise au point du vaccin et application à la prophylaxie [PDF]

open access: yes, 2000
La variole cameline est une pathologie majeure de l'espèce. Le virus (Orthopoxvirus cameli) a pu être isolé au Maroc. La souche isolée après huit passages sur cellules Vero a été dénommée T8.
El Harrak, Mehdi, Loutfi, C.
core   +2 more sources

A Nucleic Acid-Based Orthopoxvirus Vaccine Targeting the Vaccinia Virus L1, A27, B5, and A33 Proteins Protects Rabbits against Lethal Rabbitpox Virus Aerosol Challenge

open access: yesJournal of Virology, 2021
The eradication of smallpox and subsequent cessation of vaccination have left a majority of the population susceptible to variola virus or other emerging poxviruses. This is exemplified by human monkeypox, as evidenced by the increase in reported endemic
E. Mucker   +8 more
semanticscholar   +1 more source

Seasonality of human orthopoxvirus infections

open access: yes, 2022
Variola infections (smallpox) showed seasonality in temperate climates. This sharp seasonality (peaking in the Winter-Spring) may have important ramifications for control and elimination of human monkeypox (MPX) and should be considered in planning public health response.
Andrew Lover, Andrew Noymer
openaire   +1 more source

Orthopoxvirus-specific antibodies wane to undetectable levels 1 year after MVA-BN vaccination of at-risk individuals, the Netherlands, 2022 to 2023

open access: yesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
In response to the mpox outbreak in 2022 and 2023, widespread vaccination with modified vaccinia Ankara-Bavarian Nordic (MVA-BN, also known as JYNNEOS or Imvanex) was initiated.
L. V. van Leeuwen   +13 more
semanticscholar   +1 more source

Orthopoxvirus infection transmitted by a domestic cat

open access: yesJournal of the American Academy of Dermatology, 2006
The variola virus was declared eradicated by the World Health Organization in 1980 but human infections by cowpox virus, another member of the genus Orthopoxvirus, are still observed, mainly in European countries. We report a woman who presented with two umbilicated vesicles surrounded by an indurated erythematous edema within cat scratch injuries on ...
Haenssle, Holger Andreas   +5 more
openaire   +4 more sources

Orthopoxvirus Targets for the Development of Antiviral Therapies [PDF]

open access: yesCurrent Drug Target -Infectious Disorders, 2005
The potential use of smallpox virus as a bioterror agent and the endemic presence of monkeypox virus in Africa underscores the need for better therapies for orthopoxvirus infections. The only existing clinical experience treating vaccinia and smallpox infections has been with Marboran, which suggested that antiviral therapies could be effective in ...
Earl R. Kern, Mark N. Prichard
openaire   +3 more sources

Synergistic effect of two human-like monoclonal antibodies confers protection against orthopoxvirus infection

open access: yesNature Communications
The eradication of smallpox was officially declared by the WHO in 1980, leading to discontinuation of the vaccination campaign against the virus. Consequently, immunity against smallpox and related orthopoxviruses like Monkeypox virus gradually declines,
H. Tamir   +16 more
semanticscholar   +1 more source

Cowpox after a cat scratch – case report from Poland

open access: yesAnnals of Agricultural and Environmental Medicine, 2015
Cowpox in humans is a rare zoonotic disease; its recognition is therefore problematic due to the lack of clinical experience. The differential diagnosis includes other poxvirus infections and also infections with herpesviruses or selected bacteria.
Karolina Świtaj   +3 more
doaj   +1 more source

Rapid bedside inactivation of Ebola virus for safe nucleic acid tests [PDF]

open access: yes, 2016
Rapid bedside inactivation of Ebola virus would be a solution for the safety of medical and technical staff, risk containment, sample transport and high-throughput or rapid diagnostic testing during an outbreak.
Bragstad, Karoline   +9 more
core   +1 more source

An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications

open access: yesExpert Review of Anti-Infective Therapy, 2020
Introduction Tecovirimat (TPOXX®; ST-246) was approved for the treatment of symptomatic smallpox by the USFDA in July of 2018 and has been stockpiled by the US government for use in a smallpox outbreak.
Andrew T. Russo   +8 more
semanticscholar   +1 more source

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