Results 81 to 90 of about 11,507 (279)

Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily [PDF]

, 2015
Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any ...
Alcami, Alejo, Altekar, Altschul, Baker, Buatois, Bursill, Byun, Christopher Nelson, Clark, Dabbagh, Daved Fremont, Deane, Finn, Graham, Hendrickson, Hnatiuk, Jabari Elliott, Kelley, Kelley, Lalani, Lateef, Lateef, Lee, Lin, Loparev, McCoy, Megan Epperson, Ng, Pelham, Reading, Rozwarski, Ruiz-Arguello, Seet, Silverman, Smith, Sukrit Singh, Upton, Werden, White, Wilkins   +40 more
core   +3 more sources

Genesis of Monkeypox

Journal of Pure and Applied Microbiology, 2022
A zoonotic orthopoxvirus known as monkeypox inadvertently produces a smallpox-like illness in humans but with far fewer fatalities. This infection is indigenous to most parts of the African continent, with outbreaks throughout the Western World linked to
Abdul Basit, Jasni Mohamad Zain, Hafiza Zoya Mojahid, Mushtaq Ali   +3 more
doaj   +1 more source

Outbreak of gastroenteritis caused by Yersinia pestis in Afghanistan. [PDF]

, 2011
Plague, which is most often caused by the bite of Yersinia pestis-infected fleas, is a rapidly progressing, serious disease that can be fatal without prompt antibiotic treatment.
Ayazi, E, Baldwin, C, Hami, AS, Kakar, F, Kakar, R, Leslie, T, Mofleh, J, Mustafa, L, Noormal, B, Omar, F, Rossi, C, Whitehouse, CA, Yingst, S, Ziar, N   +13 more
core   +1 more source

Comparative pathogenicity of vaccinia virus and mpox virus infections in CAST/EiJ mice: Exploring splenomegaly and transcriptomic profiles

Animal Models and Experimental Medicine, EarlyView.
We successfully constructed CAST/EiJ mice models infected with low‐dose vaccinia virus (VACV‐L), high‐dose VACV (VACV‐H), and mpox virus (MPXV), demonstrating that VACV‐L and MPXV infections induced splenomegaly in mice, and VACV‐H infection caused mortality in mice.
Yongzhi Hou, Jianrong Ma, Baoying Huang, Na Li, Lin Zhu, Ziqing Jia, Jiasen Yang, Jingjing Zhang, Wenjie Tan, Jing Xue   +9 more
wiley   +1 more source

The impact of antigenic distance on Orthopoxvirus Vaccination and Mpox Infection for cross-protective immunity

medRxiv
Immunological memory mediates rapid protection following infection or vaccination including heterologous exposure. However, cross-reactive memory responses in humans remain poorly characterized.
Jameson Crandell, V. Monteiro, Lauren Pischel, Z. Fang, Yi Zhong, Lauren Lawres, Luciana Conde, Gustavo Meira de Asis, Gabriela Maciel, Agnieszka Zaleski, Guilherme S Lira, L. Higa, M. Breban, C. Vogels, N. Grubaugh, Lydia Aoun-Barakat, A. Grifoni, Alessandro Sette, T. Castiñeiras, Sidi Chen, Inci Yildirim, Andre M Vale, Saad B. Omer, C. Lucas   +23 more
semanticscholar   +1 more source

(+)‐Camphor and (−)‐borneol derivatives as potential anti‐orthopoxvirus agents

Archiv der Pharmazie, 2021
Although the World Health Organisation had announced that smallpox was eradicated over 40 years ago, the disease and other related pathogenic poxviruses such as monkeypox remain potential bioterrorist weapons and could also re‐emerge as natural ...
A. Sokolova, Kseniya S. Kovaleva, O. Yarovaya, N. I. Bormotov, L. Shishkina, O. Serova, A. Sergeev, A. Agafonov, Rinat A Maksuytov, N. Salakhutdinov   +9 more
semanticscholar   +1 more source

Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, EarlyView.
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary, Lucky Lucky, Harsh Sable, Nikhil Bhalla   +3 more
wiley   +1 more source

Conservation and Variation in Orthopoxvirus Genome Structure

Journal of General Virology, 1979
Orthopoxvirus DNA from representative strains of rabbitpox, vaccinia, monkeypox, variola, cowpox and ectromelia viruses was analysed by cleavage with restriction endonucleases HindIII, XhoI or SmaI. Genome mol. wt. vary from about 120 x 10(6) for rabbitpox to about 145 x 10(6) for cowpox.
M. Mackett, L. C. Archard
openaire   +3 more sources

Effects of georeferencing effort on mapping monkeypox case distributions and transmission risk [PDF]

, 2012
Background Maps of disease occurrences and GIS-based models of disease transmission risk are increasingly common, and both rely on georeferenced diseases data.
Carroll Darin S, Damon Inger K, Hughes Christine M, Karem Kevin, Lash R, Nakazawa Yoshinori, Peterson A   +6 more
core   +3 more sources

Mpox (Formally Known as Monkeypox) [PDF]

, 2023
Mpox originates from the Mpox virus, which belongs to the Orthopoxvirus genus of the Poxviridae family.1, 2, 3 Other Orthopoxvirus species include the variola virus (the now eradicated smallpox virus), vaccinia virus (a virus used in the creation of the ...
Bester, Vanessa, Browne, Frederick, LePage, Tricia, Nemec, Eric C., O\u27Neill, Molly, Yoon, Henry   +5 more
core   +2 more sources