Results 81 to 90 of about 11,628 (248)

Whole genome sequencing of recombinant viruses obtained from co-infection and superinfection of Vero cells with modified vaccinia virus ankara vectored influenza vaccine and a naturally occurring cowpox virus

Frontiers in Immunology
Modified vaccinia virus Ankara (MVA) has been widely tested in clinical trials as recombinant vector vaccine against infectious diseases and cancers in humans and animals.
Diana Diaz-Cánova, Ugo Moens, Annika Brinkmann, Andreas Nitsche, Malachy Ifeanyi Okeke   +4 more
doaj   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

Advanced Science, Volume 12, Issue 26, July 10, 2025.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su, Guoqing Wu, Muya Xiong, Yuhang Wang, Junyuan Cao, Mengyuan You, Yingchun Xiang, Tianqing Nie, Minjun Li, Gengfu Xiao, Leike Zhang, Qiang Shao, Yechun Xu   +12 more
wiley   +1 more source

Low Specific T‐Cell Immunity Against Mpox Elicited in People With HIV‐1 and PrEP Users After Subcutaneous Vaccination Compared to Natural Infection

Journal of Medical Virology, Volume 97, Issue 7, July 2025.
ABSTRACT In August 2024, the World Health Organization declared mpox infection a Public Health Emergency of International Concern for second time since 2022 and recommended vaccinating all people at‐risk, such as people with HIV‐1 (PWH) and prophylaxis pre‐exposition (PrEP) users.
Olivia de la Calle‐Jiménez, Guiomar Casado‐Fernández, Inés Armenteros‐Yeguas, Luis Lemus‐Aguilar, Begoña Baza, Jorge Alfredo Pérez‐García, Javier Rodríguez‐Añover, Elena Mateos, Reynaldo Homen, Eva Orviz‐García, Noemí Cabello, Anabel Negredo, María Paz Sánchez Seco, Jorge del Romero, Vicente Estrada, Montserrat Torres, Mayte Coiras   +16 more
wiley   +1 more source

Co-Circulating Monkeypox and Swinepox Viruses, Democratic Republic of the Congo, 2022

Emerging Infectious Diseases
In September 2022, deaths of pigs manifesting pox-like lesions caused by swinepox virus were reported in Tshuapa Province, Democratic Republic of the Congo. Two human mpox cases were found concurrently in the surrounding community.
Thierry Kalonji, Emile Malembi, Jean Paul Matela, Toutou Likafi, Eddy Kinganda-Lusamaki, Emmanuel Hasivirwe Vakaniaki, Nicole A. Hoff, Amuri Aziza, Francisca Muyembe, Joelle Kabamba, Tine Cooreman, Béatrice Nguete, Danae Witte, Ahidjo Ayouba, Nicolas Fernandez-Nuñez, Stijn Roge, Martine Peeters, Sydney Merritt, Steve Ahuka-Mundeke, Eric Delaporte, Elisabeth Pukuta, Joachim Mariën, Eugene Bangwen, Steven Lakin, Charles Lewis, Jeffrey B. Doty, Laurens Liesenborghs, Lisa E. Hensley, Andrea McCollum, Anne W. Rimoin, Jean Jacques Muyembe-Tamfum, Robert Shongo, Didine Kaba, Placide Mbala-Kingebeni   +33 more
doaj   +1 more source

Identification of Novel Cetacean Poxviruses in Cetaceans Stranded in South West England [PDF]

, 2015
Poxvirus infections in marine mammals have been mainly reported through their clinical lesions and electron microscopy (EM). Poxvirus particles in association with such lesions have been demonstrated by EM and were previously classified as two new ...
Barnett, J, Dastjerdi, A, Davison, N, Deaville, R, Everest, D, Finnegan, C, Jepson, P, Peake, J, Steinbach, F   +8 more
core  

Sporotrichosis caused by sporothrix mexicana, Portugal [PDF]

, 2011
Sporotrichosis is a subcutaneous fungal infection present worldwide that is caused by traumatic inoculation or inhalation of spores of the dimorphic fungus Sporothrix schenckii complex (1-3). However, molecular studies have shown that the S.
Dias, Nicolina, Lima, Nelson, Oliveira, M. M. E., Portela, M., Santos, C., Zancope-Oliveira, R. M.   +5 more
core   +3 more sources

Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, Volume 6, Issue 7, July 2025.
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary, Lucky Lucky, Harsh Sable, Nikhil Bhalla   +3 more
wiley   +1 more source

Proctitis and Other Gastrointestinal Manifestations in Mpox Disease: A Systematic Review and Meta‐Analysis

JGH Open, Volume 9, Issue 6, June 2025.
ABSTRACT Background Mpox, caused by the monkeypox virus (MPXV), is primarily recognized for its dermatologic and systemic symptoms. However, emerging evidence suggests a significant prevalence of gastrointestinal (GI) manifestations, particularly proctitis, diarrhea, nausea, vomiting, and abdominal pain.
Prakasini Satapathy, Abhay M. Gaidhane, Nasir Vadia, Soumya V. Menon, Kattela Chennakesavulu, Rajashree Panigrahi, Sanjit Sah, Suraj Tiwari, S. Govinda Rao, Khang Wen Goh, Rachana Mehta, Muhammed Shabil, Mahendra Singh, Ganesh Bushi   +13 more
wiley   +1 more source

Orthopoxvirus Infections: Epidemiology, Clinical Picture, and Diagnostics (Scientific Review)

Проблемы особо опасных инфекций, 2013
Lack of immunity among the population against pathogenic orthopoxviruses and an increased number of these infections human cases testify to the need of development of the rapid high-sensitive methods for species-specific orthopoxvirus diagnostics.
E. V. Gavrilova, R. A. Maksyutov, S. N. Shchelkunov   +2 more
doaj   +1 more source

Effects of georeferencing effort on mapping monkeypox case distributions and transmission risk [PDF]

, 2012
Background Maps of disease occurrences and GIS-based models of disease transmission risk are increasingly common, and both rely on georeferenced diseases data.
Carroll Darin S, Damon Inger K, Hughes Christine M, Karem Kevin, Lash R, Nakazawa Yoshinori, Peterson A   +6 more
core   +3 more sources