The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG +6 more
core +1 more source
ABSTRACT In the wake of the COVID‐19 pandemic, awareness of emerging pathogens has significantly increased, prompting greater investment in research and preparedness. In this context, arboviral diseases are recognized as unmet medical challenges due to their rapid spread. Notably, the geographical range of several flaviviral diseases is expanding: Zika
Erika Plicanti +11 more
wiley +1 more source
Orthopoxvirus infection transmitted by a domestic cat
The variola virus was declared eradicated by the World Health Organization in 1980 but human infections by cowpox virus, another member of the genus Orthopoxvirus, are still observed, mainly in European countries. We report a woman who presented with two umbilicated vesicles surrounded by an indurated erythematous edema within cat scratch injuries on ...
Haenssle, Holger Andreas +5 more
openaire +3 more sources
Co-Circulating Monkeypox and Swinepox Viruses, Democratic Republic of the Congo, 2022
In September 2022, deaths of pigs manifesting pox-like lesions caused by swinepox virus were reported in Tshuapa Province, Democratic Republic of the Congo. Two human mpox cases were found concurrently in the surrounding community.
Thierry Kalonji +33 more
doaj +1 more source
Diagnostic electron microscopy in human infectious diseases – Methods and applications
Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley +1 more source
Exceptional Clinical Resistance and Variable Reservoir Competence [PDF]
Cowpox virus (CPXV) is a zoonotic virus and endemic in wild rodent populations in Eurasia. Serological surveys in Europe have reported high prevalence in different vole and mouse species.
Beer, Martin +6 more
core +1 more source
Identification of Novel Cetacean Poxviruses in Cetaceans Stranded in South West England [PDF]
Poxvirus infections in marine mammals have been mainly reported through their clinical lesions and electron microscopy (EM). Poxvirus particles in association with such lesions have been demonstrated by EM and were previously classified as two new ...
Barnett, J +8 more
core
Effects of georeferencing effort on mapping monkeypox case distributions and transmission risk [PDF]
Background Maps of disease occurrences and GIS-based models of disease transmission risk are increasingly common, and both rely on georeferenced diseases data.
Carroll Darin S +6 more
core +3 more sources
Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su +12 more
wiley +1 more source
Sporotrichosis caused by sporothrix mexicana, Portugal [PDF]
Sporotrichosis is a subcutaneous fungal infection present worldwide that is caused by traumatic inoculation or inhalation of spores of the dimorphic fungus Sporothrix schenckii complex (1-3). However, molecular studies have shown that the S.
Dias, Nicolina +5 more
core +3 more sources

