Results 1 to 10 of about 1,556,220 (331)

Adrenergic regulation of immune cell function and inflammation

Seminars in Immunopathology, 2020
The sympathetic nervous system integrates the functions of multiple organ systems by regulating their autonomic physiological activities. The immune system is regulated both locally and systemically by the neurotransmitters epinephrine and norepinephrine
D. Sharma, J. Farrar
semanticscholar   +1 more source

Synchronization of oscillatory growth prepares fungal hyphae for fusion

eLife, 2023
Communication is crucial for organismic interactions, from bacteria, to fungi, to humans. Humans may use the visual sense to monitor the environment before starting acoustic interactions.
Valentin Wernet, Marius Kriegler, Vojtech Kumpost, Ralf Mikut, Lennart Hilbert, Reinhard Fischer   +5 more
doaj   +1 more source

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

Cell, 2018
Summary How signaling dynamics encode information is a central question in biology. During vertebrate development, dynamic Notch signaling oscillations control segmentation of the presomitic mesoderm (PSM).
Katharina F. Sonnen, Volker M. Lauschke, Julia Uraji, Henning J Falk, Yvonne Petersen, Maja C. Funk, Mathias Beaupeux, P. François, C. Merten, A. Aulehla   +9 more
semanticscholar   +1 more source

Blockage of spontaneous Ca2+ oscillation causes cell death in intraerythrocitic Plasmodium falciparum. [PDF]

PLoS ONE, 2012
Malaria remains one of the world's most important infectious diseases and is responsible for enormous mortality and morbidity. Resistance to antimalarial drugs is a challenging problem in malaria control.
Masahiro Enomoto, Shin-ichiro Kawazu, Satoru Kawai, Wakako Furuyama, Tohru Ikegami, Jun-ichi Watanabe, Katsuhiko Mikoshiba   +6 more
doaj   +1 more source

Messages across time and space

eLife, 2020
Compartmentalized oscillations of second messengers affect global cellular signaling.
Sascha M Kuhn, André Nadler
doaj   +1 more source

Conservation and divergence of p53 oscillation dynamics across species

Cell Systems, 2017
Summary The tumor suppressing transcription factor p53 is highly conserved at the protein level and plays a key role in the DNA damage response. One important aspect of p53 regulation is its dynamics in response to DNA damage, which include oscillations.
Jacob Stewart-Ornstein, H. Cheng, G. Lahav   +2 more
semanticscholar   +1 more source

Receptor-specific Ca2+ oscillation patterns mediated by differential regulation of P2Y purinergic receptors in rat hepatocytes

iScience, 2021
Summary: Extracellular agonists linked to inositol-1,4,5-trisphosphate (IP3) formation elicit cytosolic Ca2+ oscillations in many cell types, but despite a common signaling pathway, distinct agonist-specific Ca2+ spike patterns are observed.
Juliana C. Corrêa-Velloso, Paula J. Bartlett, Robert Brumer, Lawrence D. Gaspers, Henning Ulrich, Andrew P. Thomas   +5 more
doaj   +1 more source

The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

iScience, 2023
Summary: Circadian clock controls daily behavior and physiology. The activity of various signaling pathways affects clock gene expression. Here, we show that the core circadian clock gene CRY1 is a direct target of the Hippo pathway effector YAP.
Abdelhalim Azzi, Zhipeng Tao, Yang Sun, Hannah Erb, Carla Guarino, Xu Wu   +5 more
doaj   +1 more source

Single cell resolution imaging of the impact of Notch signaling and mitosis on segmentation clock dynamics

Developmental Cell, 2012
Summary Vertebrate body segmentation is controlled by the segmentation clock, a molecular oscillator involving transcriptional oscillations of cyclic genes in presomitic mesoderm cells.
Emilie A Delaune, P. François, Nathan P. Shih, S. Amacher   +3 more
semanticscholar   +1 more source

Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-related bone loss via miR142-3p/Bmal1/YAP signaling axis

Cell Death Discovery, 2022
Age-related bone loss and disease strongly affect the quality of life of the elderly population. Cellular circadian rhythms have been reported to regulate bone aging, and micro RNAs (miRNAs) play crucial posttranscriptional regulatory roles in the ...
Sa Cha, Jiangyue Wang, Sueng Min Lee, Zhen Tan, Qing Zhao, Ding Bai   +5 more
doaj   +1 more source