A Rho family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. [PDF]
Tip growth in neuronal cells, plant cells, and fungal hyphae is known to require tip-localized Rho GTPase, calcium, and filamentous actin (F-actin), but how they interact with each other is unclear.
Dowd, Peter+6 more
core +3 more sources
Ca 2+ oscillation frequency decoding in cardiac cell hypertrophy: Role of calcineurin/NFAT as Ca 2+ signal integrators [PDF]
The role of Ca 2+ signaling in triggering hypertrophy was investigated in neonatal rat cardiomyocytes in vitro . We show that an increase in cell size and sarcomere reorganization were elicited by receptor agonists such as Angiotensin II, aldosterone, and norepinephrine and by a small rise in
Colella M+5 more
openaire +5 more sources
The fabrication and post‐treatment via solvent annealing of poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate‐based electrodes using spray deposition in a roll‐to‐roll setup are presented. The decrease in sheet resistance and its correlation with nanostructure and molecular structure in the electrodes as a function of the processing parameters is ...
Marie Betker+10 more
wiley +1 more source
Ultrahigh Piezoelectricity in Truss‐Based Ferroelectric Ceramics Metamaterials
By leveraging the unique combination of polarization direction and loading state, ultrahigh piezoelectricity is achieved through careful tuning of the relative density and scaling ratio in truss‐based ferroelectric metamaterials. This approach enables the simultaneous realization of extremely high piezoelectric constants and ultralow dielectric ...
Jiahao Shi+6 more
wiley +1 more source
Multiplexing oscillatory biochemical signals
In recent years it is increasingly being recognized that biochemical signals are not necessarily constant in time and that the temporal dynamics of a signal can be the information carrier.
de Ronde, Wiet, Wolde, Pieter Rein ten
core +1 more source
Stimulation of electro-olfactogram responses in the main olfactory epithelia by airflow depends on the type 3 adenylyl cyclase [PDF]
Cilia of olfactory sensory neurons are the primary sensory organelles for olfaction. The detection of odorants by the main olfactory epithelium (MOE) depends on coupling of odorant receptors to the type 3 adenylyl cyclase (AC3) in olfactory cilia.
Chen, Xuanmao+2 more
core +2 more sources
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski+9 more
wiley +1 more source
Multiscale modeling of oscillations and spiral waves in Dictyostelium populations
Unicellular organisms exhibit elaborate collective behaviors in response to environmental cues. These behaviors are controlled by complex biochemical networks within individual cells and coordinated through cell-to-cell communication.
Gregor, Thomas+4 more
core +1 more source
Repetitive mitochondrial Ca 2+ signals synchronize with cytosolic Ca 2+ oscillations in the pancreatic beta-cell line, MIN6 [PDF]
We examined the relationship between cytosolic Ca2+ concentration ([Ca2+]c) and mitochondrial matrix Ca2+ concentration ([Ca2+]m) in the pancreatic beta-cell line, MIN6. [Ca2+]c was monitored in a single or a group (30 cells) of fura-2-loaded MIN6 cells, and [Ca2+]m was measured in a group (1 x 10[6] cells) of MIN6 cells stably transfected with ...
Tomoichiro Asano+9 more
openaire +3 more sources
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong+7 more
wiley +1 more source