Results 51 to 60 of about 1,282,481 (350)

Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance. [PDF]

, 2019
Circadian clocks control daily rhythms in behavior and physiology. In Drosophila, the small ventral lateral neurons (sLNvs) expressing PIGMENT DISPERSING FACTOR (PDF) are the master pacemaker neurons generating locomotor rhythms.
Cai, Yao, Chiu, Joanna C, Lam, Vu H, Liu, Zhenxing, Mcintire, Pearson, Niu, Ye, Tabuloc, Christine A, Xue, Yongbo, Zhang, Yong   +8 more
core   +1 more source

Spontaneous calcium signaling of cartilage cells: from spatiotemporal features to biophysical modeling

The FASEB Journal, 2019
Intracellular calcium ([Ca2+]i) oscillation is a fundamental signaling response of cartilage cells under mechanical loading or osmotic stress. Chondrocytes are usually considered as nonexcitable cells with no spontaneous [Ca2+]i signaling.
Yilu Zhou, Mengxi Lv, Tong Li, Tiange Zhang, R. Duncan, Liyun Wang, X. Lucas Lu   +6 more
semanticscholar   +1 more source

Genetic disruption of the core circadian clock impairs hippocampus-dependent memory [PDF]

, 2014
Perturbing the circadian system by electrolytically lesioning the suprachiasmatic nucleus (SCN) or varying the environmental light:dark schedule impairs memory, suggesting that memory depends on the circadian system.
Chen, Xuanmao, Phan, Trongha X., Saraf, Amit, Storm, Daniel R., Wardlaw, Sarah M.   +4 more
core   +2 more sources

The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

iScience, 2023
Summary: Circadian clock controls daily behavior and physiology. The activity of various signaling pathways affects clock gene expression. Here, we show that the core circadian clock gene CRY1 is a direct target of the Hippo pathway effector YAP.
Abdelhalim Azzi, Zhipeng Tao, Yang Sun, Hannah Erb, Carla Guarino, Xu Wu   +5 more
doaj   +1 more source

Mathematical models for somite formation [PDF]

, 2007
Somitogenesis is the process of division of the anterior–posterior vertebrate embryonic axis into similar morphological units known as somites. These segments generate the prepattern which guides formation of the vertebrae, ribs and other associated ...
Armstrong, Aulehla, Aulehla, Aulehla, Baker, Baker, Baker, Chernoff, Collier, Cooke, Cooke, Cooke, Dale, Dale, Dale, del Barco Barrantes, Dequéant, Diez del Corral, Diez del Corral, Diez del Corral, Drake, Duband, Dubrulle, Dubrulle, Dubrulle, Dubrulle, Duguay, Foty, Galli, Giudicelli, Goldbeter, Gossler, Grima, Haraguichi, Hirata, Horikawa, Ishikawa, Jiang, Jiang, Kalcheim, Kulesa, Lewis, Maroto, McGrew, McGrew, McInerney, Meier, Molotkova, Monk, Moreno, Morimoto, Packard, Packard, Palmeirim, Pourquié, Pourquié, Pourquié, Pourquié, Pourquié, Pourquié, Primmett, Primmett, Rida, Saga, Schnell, Schnell, Schnell, Stockdale, Tabin, Takahashi, Takashi, Tam, Turner   +72 more
core   +1 more source

Optogenetic perturbation and bioluminescence imaging to analyze cell-to-cell transfer of oscillatory information.

Genes & Development, 2017
Cells communicate with each other to coordinate their gene activities at the population level through signaling pathways. It has been shown that many gene activities are oscillatory and that the frequency and phase of oscillatory gene expression encode ...
Akihiro Isomura, F. Ogushi, H. Kori, R. Kageyama   +3 more
semanticscholar   +1 more source

Resonance in the Mouse Ventral Tegmental Area Dopaminergic Network Induced by Regular and Poisson Distributed Optogenetic Stimulation in-vitro

Frontiers in Computational Neuroscience, 2020
Neurons in many brain regions exhibit spontaneous, intrinsic rhythmic firing activity. This rhythmic firing activity may determine the way in which these neurons respond to extrinsic synaptic inputs. We hypothesized that neurons should be most responsive
Luuk van der Velden, Martin A. Vinck, Wytse J. Wadman   +2 more
doaj   +1 more source

Collective cell migration of Dictyostelium without cAMP oscillations at multicellular stages

Communications Biology, 2019
In Dictyostelium discoideum, a model organism for the study of collective cell migration, extracellular cyclic adenosine 3’,5’-monophosphate (cAMP) acts as a diffusible chemical guidance cue for cell aggregation, which has been thought to be important in
Hidenori Hashimura, Yusuke V. Morimoto, M. Yasui, M. Ueda   +3 more
semanticscholar   +1 more source

A Rho family GTPase controls actin dynamics and tip growth via two counteracting downstream pathways in pollen tubes. [PDF]

, 2005
Tip growth in neuronal cells, plant cells, and fungal hyphae is known to require tip-localized Rho GTPase, calcium, and filamentous actin (F-actin), but how they interact with each other is unclear.
Dowd, Peter, Fu, Ying, Gilroy, Simon, Gu, Ying, Li, Shundai, Vernoud, Vanessa, Yang, Zhenbiao   +6 more
core   +3 more sources

Human iNKT Cells Promote Protective Inflammation by Inducing Oscillating Purinergic Signaling in Monocyte-Derived DCs [PDF]

Cell Reports, 2016
Invariant natural killer T (iNKT) cells are innate T lymphocytes that promote host defense against a variety of microbial pathogens. Whether microbial ligands are required for their protective effects remains unclear. Here, we show that iNKT cells stimulate human-monocyte-derived dendritic cells (DCs) to produce inflammatory mediators in a manner that ...
Nathan M. Sherer, Bruce S. Klein, Erwin Berthier, Xuequn Xu, Jenny E. Gumperz, Laura Felley, J. Scott Fites, Douglas Stewart, Stephen L. Peery, Ginger M. Pocock, Akshat Sharma, Robert Zarnowski   +11 more
openaire   +4 more sources