Results 1 to 10 of about 42,609 (234)

Comparative effectiveness of oseltamivir versus peramivir for hospitalized children (aged 0-5 years) with influenza infection

open access: yesInternational Journal of Infectious Diseases, 2023
Objectives: The effectiveness of oseltamivir versus peramivir in children infected with influenza remains unclear. This study aimed to evaluate their effectiveness in young children (aged 0-5 years) infected with severe influenza A virus (IAV) or ...
Ming Xu   +16 more
doaj   +2 more sources

Evaluating the effects of oseltamivir phosphate on platelet counts: a retrospective review

open access: yesPlatelets, 2020
Desialylation of platelets results in platelet clearance by the Ashwell-Morrell Receptors (AMR) found on hepatocytes. Studies suggest that oseltamivir phosphate inhibits human sialidases, enzymes responsible for desialylation, extending the lifespan of ...
Hila Shaim   +4 more
doaj   +2 more sources

Binding mechanism of oseltamivir and influenza neuraminidase suggests perspectives for the design of new anti-influenza drugs.

open access: yesPLoS Computational Biology, 2022
Oseltamivir is a widely used influenza virus neuraminidase (NA) inhibitor that prevents the release of new virus particles from host cells. However, oseltamivir-resistant strains have emerged, but effective drugs against them have not yet been developed.
Jiaye Tao   +18 more
doaj   +1 more source

A Cross-Sectional Study of Psychiatric Manifestations Following Oseltamivir Administration for Suspected Patients with H1N1 Swine Influenza Infection [PDF]

open access: yesJournal of Cardio-Thoracic Medicine, 2022
Introduction: Oseltamivir is an antiviral drug used to treat H1N1 influenza. FDA added a warning to the label of oseltamivir drawing attention to the risk of developing neuropsychiatric adverse events.
Basavaraju Jayadeva   +3 more
doaj   +1 more source

Oseltamivir

open access: yesJournal of Postgraduate Medicine, 2009
Oseltamivir, a selective neuraminidase enzyme inhibitor, has gained worldwide attention in view of Influenza A (H1N1) pandemic. It is one of the most important drugs effective against the novel influenza virus. Oseltamivir is used for the treatment of uncomplicated acute illness due to influenza infection.
  +5 more sources

A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir

open access: yesVirology Journal, 2010
Background Oseltamivir is the preferred antiviral drug for influenza, but oseltamivir-resistant A(H1N1) viruses have circulated worldwide since the 2007-2008 influenza season.
Itagaki Tsutomu   +13 more
doaj   +1 more source

Anti-influenza neuraminidase inhibitor oseltamivir phosphate induces canine mammary cancer cell aggressiveness. [PDF]

open access: yesPLoS ONE, 2015
Oseltamivir phosphate is a widely used anti-influenza sialidase inhibitor. Sialylation, governed by sialyltransferases and sialidases, is strongly implicated in the oncogenesis and progression of breast cancer.
Joana T de Oliveira   +10 more
doaj   +1 more source

Distribution of selected healthcare resources for influenza pandemic response in Cambodia. [PDF]

open access: yes, 2013
INTRODUCTION: Human influenza infection poses a serious public health threat in Cambodia, a country at risk for the emergence and spread of novel influenza viruses with pandemic potential.
Borin, Khieu   +7 more
core   +3 more sources

Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir. [PDF]

open access: yesPLoS ONE, 2015
Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses.
Eun-Hye Hong   +13 more
doaj   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

open access: yes, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi   +99 more
core   +2 more sources

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