Results 21 to 30 of about 87,991 (243)

Osteoblastic Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth by Probiotic Hydroxyapatite [PDF]

Cell Journal, 2023
Objective: Multipotent cells derived from human exfoliated deciduous teeth (SHED) possess the ability to differentiateinto various cell types, including osteoblasts.
Sabere Nouri, Rasoul Roghanian, Giti Emtiazi, Oguzhan Gunduz, Rasoul Shafiei   +4 more
doaj   +1 more source

Neural Cell Adhesion Molecule Regulates Osteoblastic Differentiation Through Wnt/β-Catenin and PI3K-Akt Signaling Pathways in MC3T3-E1 Cells

Frontiers in Endocrinology, 2021
Neural cell adhesion molecule (NCAM) is involved in cell multi-directional differentiation, but its role in osteoblast differentiation is still poorly understood.
Bin-Feng Cheng, Xiao Feng, Yao-Xin Gao, Shao-Qin Jian, Shi-Rao Liu, Mian Wang, Yun-Fei Xie, Lei Wang, Zhi-Wei Feng, Hai-Jie Yang, Hai-Jie Yang   +10 more
doaj   +1 more source

Osteoblast–osteoclast interactions [PDF]

Connective Tissue Research, 2017
Bone homeostasis depends on the resorption of bones by osteoclasts and formation of bones by the osteoblasts. Imbalance of this tightly coupled process can cause diseases such as osteoporosis. Thus, the mechanisms that regulate communication between osteoclasts and osteoblasts are critical to bone cell biology.
Xiao, Chen, Zhongqiu, Wang, Na, Duan, Guoying, Zhu, Edward M, Schwarz, Chao, Xie   +5 more
openaire   +2 more sources

E3 Ubiquitin Ligase-Mediated Regulation of Osteoblast Differentiation and Bone Formation

Frontiers in Cell and Developmental Biology, 2021
The ubiquitin–proteasome system (UPS) is an essential pathway that regulates the homeostasis and function of intracellular proteins and is a crucial protein-degradation system in osteoblast differentiation and bone formation.
Jianlin Shen, Jianlin Shen, Bowen Fu, Yanfang Li, Yanjiao Wu, Hongxun Sang, Heshi Zhang, Haibin Lin, Huan Liu, Wenhua Huang, Wenhua Huang, Wenhua Huang   +11 more
doaj   +1 more source

Ginsenoside Re Promotes Osteoblast Differentiation in Mouse Osteoblast Precursor MC3T3-E1 Cells and a Zebrafish Model

Molecules, 2016
Bone homeostasis is tightly regulated to balance bone formation and bone resorption. Many anabolic drugs are used as bone-targeted therapeutic agents for the promotion of osteoblast-mediated bone formation or inhibition of osteoclast-mediated bone ...
Hye-Min Kim, Dong Hyun Kim, Ho-Jin Han, Chan-Mi Park, Srinivas Rao Ganipisetti, Mariadhas Valan Arasu, Young Ock Kim, Chun Geun Park, Bo-Yeon Kim, Nak-Kyun Soung   +9 more
doaj   +1 more source

Effects of Flaxseed (Linum usitatissimum) Extract on the Osteoblast Differentiation Potential of Stem Cells Derived from Human Exfoliated Deciduous Teeth

Makara Journal of Health Research, 2021
Background: Flaxseed promotes bone health and possibly induces bone regeneration. However, the capacity of flaxseed to induce the differentiation of stem cells into osteoblasts remains unreported. Accordingly, this study aimed to determine the effects of
Nur Sazwi Nordin, Khairani Idah Mokhtar, Basma Ezzat Mustafa, Widya Lestari, Solachuddin Jauhari Arief Ichwan, Deny Susanti Darnis, Thirumulu Ponnuraj Kannan, Azlina Ahmad   +7 more
doaj   +1 more source

TMEM175 plays a crucial role in osteoblast differentiation by regulating lysosomal function and autophagy

Molecules and Cells
: Bone provides structural support, enables movement, protects internal organs, regulates calcium and phosphorus levels, and contains bone marrow essential for hematopoiesis.
Seung Hye Lee, Ji Sun Jang, Shenzheng Mo, Hong-Hee Kim   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

FXR Activation Accelerates Early Phase of Osteoblast Differentiation Through COX-2-PGE₂-EP4 Axis in BMP-2-Induced Mouse Mesenchymal Stem Cells

Molecules
Farnesoid X receptor (FXR), a nuclear receptor, is expressed in calvaria and bone marrow stromal cells and plays a role in bone homeostasis. However, the mechanism of FXR-activated osteoblast differentiation remains unclear.
Ko Fujimori, Yusuke Iguchi, Yukiko Yamashita, Keigo Gohda, Naoki Teno   +4 more
doaj   +1 more source

SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts

Nature Communications, 2017
The balance between osteoclast and osteoblast-mediated bone turnover is essential for bone health and homeostasis. Here the authors show that both germline and osteoblast-specificSmurf2-deficient mice have osteoporosis as a result of increased osteoblast
Zhan Xu, Matthew B. Greenblatt, Guang Yan, Heng Feng, Jun Sun, Sutada Lotinun, Nicholas Brady, Roland Baron, Laurie H. Glimcher, Weiguo Zou   +9 more
doaj   +1 more source