Results 1 to 10 of about 18,662 (159)

The role of prostate-specific antigen in the osteoblastic bone metastasis of prostate cancer: a literature review [PDF]

Frontiers in Oncology, 2023
Prostate cancer is the only human malignancy that generates predominantly osteoblastic bone metastases, and osteoblastic bone metastases account for more than 90% of osseous metastases of prostate cancer.
Xu Zhang, Peng Jiang, Chaojun Wang
doaj   +2 more sources

A case of ROS1-rearranged lung adenocarcinoma with osteoblastic bone metastasis [PDF]

Respiratory Medicine Case Reports, 2020
A 53-year-old woman was referred to our hospital for detailed examination of abnormal chest shadows recognized on CT imaging. Transbronchial lung biopsy of a right S6 nodular shadow led to a diagnosis of lung adenocarcinoma.
Yutaka Takahara, Kouichi Yamamura, Saki Matsuura, Takashi Sakuma, Kazuaki Nishiki, Keisuke Nakase, Masafumi Nojiri, Ryo Kato, Shohei Shinomiya, Rieko Oikawa, Yuki Fujimoto, Taku Oikawa, Kazuhiro Osanai, Yoshimichi Ueda, Shiro Mizuno   +14 more
doaj   +2 more sources

Changes in Osteoblastic Bone Metastasis Detected Incidentally by Cone-Beam Computed Tomography: A Case Report [PDF]

Case Reports in Oncology
Introduction: Although cone-beam computed tomography (CBCT) is essential for tumor positioning in image-guided radiotherapy, its diagnostic application is limited by low image quality.
Uchina Hiya, Masashi Endo, Kohei Okada, Satoru Takahashi, Kazunari Ogawa, Machi Nakagawa, Michiko Nakamura, Chiaki Shibayama, Yukiko Fukuda, Keiko Akahane, Masahiro Kawahara, Harushi Mori, Katsuyuki Shirai   +12 more
doaj   +2 more sources

Determination and clinical features of bone pseudoprogression in metastatic breast cancer [PDF]

Frontiers in Oncology
ObjectiveBone is one of the most common sites of metastasis for breast cancer. The classification of new osteoblastic lesions as progressive disease is currently controversial.
Ting Xu, Yikun Ma, Lili Zhang, Shiyi Li, Min Dong, Yuan Yuan   +5 more
doaj   +2 more sources

The regulatory networks and mechanisms of bone microenvironment in tumorigenesis and metastasis [PDF]

Journal of Bone Oncology
Bone tumors, encompassing heterogeneous primary and metastatic lesions, are driven in their initiation, progression, and metastasis by dysregulation of the bone microenvironment (BME).
Guofang Huang, Tianhui Hou, Dianwen Song, Tong Meng   +3 more
doaj   +2 more sources

Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells. [PDF]

, 2014
Annexins are a class of calcium-binding proteins with diverse functions in the regulation of lipid rafts, inflammation, fibrinolysis, transcriptional programming and ion transport.
Genetos, Damian C, Karin, Norman J, Weber, Thomas J, Wong, Alice, Yellowley, Clare E   +4 more
core   +11 more sources

Wnt1 induces osteoblastic changes in a well‐established osteolytic skeletal metastatic model derived from breast cancer

Cancer Reports, 2023
Background Osteoblastic skeletal metastasis is frequently observed in prostate cancer. An effective therapy has not been developed due to the unclear molecular mechanism.
Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Yoshiya Sugiura, Mitsuru Koizumi, Tatsuya Higashi   +5 more
doaj   +1 more source

Influence of the Different Primary Cancers and Different Types of Bone Metastasis on the Lesion-based Artificial Neural Network Value Calculated by a Computer-aided Diagnostic System,BONENAVI, on Bone Scintigraphy Images [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2017
Objective(s): BONENAVI, a computer-aided diagnostic system, is used in bone scintigraphy. This system provides the artificial neural network (ANN) and bone scan index (BSI) values.
TAKURO ISODA, SINGO BABA, YASUHIRO MARUOKA, YOSHIYUKI KITAMURA, KEIICHIRO TAHARA, MASAYUKI SASAKI, Masamitsu Hatakenaka, HIROSHI HONDA   +7 more
doaj   +1 more source

A case of lung cancer with osteoblastic metastasis diagnosed with visual impairment

Interdisciplinary Neurosurgery, 2021
Bone metastasis is relatively common in patients with lung cancers. Although there are some reports of osteolytic skull base metastasis in lung cancer, osteoblastic skull base metastasis is quite rare.
Hiroki Sato, Hidetoshi Ooigawa, Yuichiro Kikkawa, Hiroki Kurita   +3 more
doaj   +1 more source

Antagonizing exosomal miR-18a-5p derived from prostate cancer cells ameliorates metastasis-induced osteoblastic lesions by targeting Hist1h2bc and activating Wnt/β-catenin pathway

Genes and Diseases, 2023
More than 50% of prostate cancer (PCa) patients have bone metastasis with osteoblastic lesions. MiR-18a-5p is associated with the development and metastasis of PCa, but it remains unclear whether it is involved in osteoblastic lesions.
Fanchun Zeng, Chunrong Zhao, Rujie Wang, Lingyan Ren, Hao Qiu, Zhi Zou, Haibin Ding, Zhongyi Sun, Jianmei Li, Shiwu Dong   +9 more
doaj   +1 more source