Results 31 to 40 of about 82,535 (276)

Polarity of Osteoblasts and Osteoblast-like UMR-108 Cells

Journal of Bone and Mineral Research, 1999
Abstract Enveloped viruses, such as vesicular stomatitis virus (VSV) and Influenza virus, have been widely used in studying epithelial cell polarity. Viral particles of VSV-infected epithelial cells bud from the basolateral membrane, which is in contact with the internal milieu and the blood supply.
J, Ilvesaro, K, Metsikkö, K, Väänänen, J, Tuukkanen   +3 more
openaire   +2 more sources

Decorin Promotes Osteoblastic Differentiation of Human Periodontal Ligament Stem Cells

Molecules, 2022
The aim of this study is to clarify the biological functions of decorin (DCN) in the healing and regeneration of wounded periodontal tissue. We investigated the expression pattern of DCN during the healing of wounded periodontal tissue in rats by ...
Orie Adachi, Hideki Sugii, Tomohiro Itoyama, Shoko Fujino, Hiroshi Kaneko, Atsushi Tomokiyo, Sayuri Hamano, Daigaku Hasegawa, Junko Obata, Shinichiro Yoshida, Masataka Kadowaki, Risa Sugiura, Mhd Safwan Albougha, Hidefumi Maeda   +13 more
doaj   +1 more source

Cord blood-derived macrophage-lineage cells rapidly stimulate osteoblastic maturation in mesenchymal stem cells in a glycoprotein-130 dependent manner. [PDF]

PLoS ONE, 2013
In bone, depletion of osteoclasts reduces bone formation in vivo, as does osteal macrophage depletion. How osteoclasts and macrophages promote the action of bone forming osteoblasts is, however, unclear.
Tania J Fernandes, Jason M Hodge, Preetinder P Singh, Damien G Eeles, Fiona M Collier, Ian Holten, Peter R Ebeling, Geoffrey C Nicholson, Julian M W Quinn   +8 more
doaj   +1 more source

Osteoblastic cells regulate the haematopoietic stem cell niche [PDF]

Nature, 2003
Stem cell fate is influenced by specialized microenvironments that remain poorly defined in mammals. To explore the possibility that haematopoietic stem cells derive regulatory information from bone, accounting for the localization of haematopoiesis in bone marrow, we assessed mice that were genetically altered to produce osteoblast-specific, activated
L M, Calvi, G B, Adams, K W, Weibrecht, J M, Weber, D P, Olson, M C, Knight, R P, Martin, E, Schipani, P, Divieti, F R, Bringhurst, L A, Milner, H M, Kronenberg, D T, Scadden   +12 more
openaire   +2 more sources

Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease [PDF]

, 2014
Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM ...
Blum B, Eriksen EF, Klein B, Lipton A, Mundy GR, Schmitt CP, Shay G   +6 more
core   +1 more source

Osteoblastic bone metastases from renal cell carcinoma [PDF]

Radiology and Oncology, 2014
Abstract Background. RCC accounts for only 2-3% of all cancers. Due to its’ non-specific symptoms disease is often diagnosed in advanced stage. Disseminated RCC frequently produces bone metastases that are almost always highly destructive, hyper vascularized and purely osteolytic. Case report.
Gašljević, Gorana, Kavčič, Pavel, Preložnik-Zupan, Irena, Salapura, Vladka, Šeruga, Boštjan   +4 more
openaire   +4 more sources

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]

, 2017
Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu, Guillaume Mabilleau, Iepsen, Iepsen, Marie Pereira   +4 more
core   +5 more sources

Thyroid-Stimulating Hormone Favors Runx2-Mediated Matrix Mineralization in HOS and SaOS2 Cells: An In Vitro and In Silico Approach

Molecules, 2022
Osteoporosis is a skeletal disease that is both systemic and silent characterized by an unbalanced activity of bone remodeling leading to bone loss.
Ramajayam Govindan, Mohamed El-Sherbiny, Khalid Mohamed Morsy Ibraheem, Srinivasan Narasimhan, Mohamed EL-Dosoky Mohamed Salama, Fazil Ahmad, Selvaraj Jayaraman, Vishnu Priya Veeraraghavan, Srinivasan Vengadassalapathy, Surapaneni Krishna Mohan, Vidhya Rekha Umapathy, Gayathri Rengasamy, Shazia Fathima Jaffer Hussain, Maheshkumar Poomarimuthu, Senthilkumar Kalimuthu   +14 more
doaj   +1 more source

Systems Genetic Analysis of Osteoblast-Lineage Cells [PDF]

PLoS Genetics, 2012
The osteoblast-lineage consists of cells at various stages of maturation that are essential for skeletal development, growth, and maintenance. Over the past decade, many of the signaling cascades that regulate this lineage have been elucidated; however, little is known of the networks that coordinate, modulate, and transmit these signals.
Calabrese, Gina, Bennett, Brian J, Orozco, Luz, Kang, Hyun M, Eskin, Eleazar, Dombret, Carlos, De Backer, Olivier, Lusis, Aldons J, Farber, Charles R   +8 more
openaire   +6 more sources