Results 11 to 20 of about 65,828 (262)

Cold atmospheric plasma enhances osteoblast differentiation. [PDF]

PLoS ONE, 2017
This study was designed to assess the effects of cold atmospheric plasma on osteoblastic differentiation in pre-osteoblastic MC3T3-E1 cells. Plasma was irradiated directly to a culture medium containing plated cells for 5 s or 10 s. Alkaline phosphatase (
Kanako Tominami, Hiroyasu Kanetaka, Shota Sasaki, Takayuki Mokudai, Toshiro Kaneko, Yoshimi Niwano   +5 more
doaj   +4 more sources

Neural Cell Adhesion Molecule Regulates Osteoblastic Differentiation Through Wnt/β-Catenin and PI3K-Akt Signaling Pathways in MC3T3-E1 Cells

Frontiers in Endocrinology, 2021
Neural cell adhesion molecule (NCAM) is involved in cell multi-directional differentiation, but its role in osteoblast differentiation is still poorly understood.
Bin-Feng Cheng, Xiao Feng, Yao-Xin Gao, Shao-Qin Jian, Shi-Rao Liu, Mian Wang, Yun-Fei Xie, Lei Wang, Zhi-Wei Feng, Hai-Jie Yang, Hai-Jie Yang   +10 more
doaj   +1 more source

Zinc Sulfate Stimulates Osteogenic Phenotypes in Periosteum-Derived Cells and Co-Cultures of Periosteum-Derived Cells and THP-1 Cells

Life, 2021
Coupling between osteoblast-mediated bone formation and osteoclast-mediated bone resorption maintains both mechanical integrity and mineral homeostasis. Zinc is required for the formation, mineralization, growth, and maintenance of bones. We examined the
Jin-Ho Park, Su A Park, Young-Hoon Kang, So Myeong Hwa, Eun-Byeol Koh, Sun-Chul Hwang, Se Heang Oh, June-Ho Byun   +7 more
doaj   +1 more source

Osteoblast Differentiation at a Glance [PDF]

Medical Science Monitor Basic Research, 2016
Ossification is a tightly regulated process, performed by specialized cells called osteoblasts. Dysregulation of this process may cause inadequate or excessive mineralization of bones or ectopic calcification, all of which have grave consequences for human health.
Rutkovskiy, Arkady, Stensløkken, Kåre-Olav, Vaage, Ingvar Jarle   +2 more
openaire   +2 more sources

Icariin attenuates the calcification of vascular smooth muscle cells through ERα – p38MAPK pathway

Aging Medicine, 2023
Objective To investigate the relationship between icariin and the osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and the signal pathway involved.
Jieyu He, Yanjiao Wang, Junkun Zhan, Shuang Li, Yuqing Ni, Wu Huang, Limin Long, Pan Tan, Yi Wang, Youshuo Liu   +9 more
doaj   +1 more source

Fibronectin regulates calvarial osteoblast differentiation [PDF]

Journal of Cell Science, 1996
ABSTRACT The secretion of fibronectin by differentiating osteoblasts and its accumulation at sites of osteogenesis suggest that fibronectin participates in bone formation. To test this directly, we determined whether fibronectin-cell interactions regulate progressive differentiation of cultured fetal rat calvarial osteoblasts.
A M, Moursi, C H, Damsky, J, Lull, D, Zimmerman, S B, Doty, S, Aota, R K, Globus   +6 more
openaire   +2 more sources

Relaxin treatment stimulates the differentiation of mesenchymal stem cells into osteoblasts

Journal of Dental Sciences, 2023
Background/purpose: Several studies have determined that relaxin stimulates differentiation and regulates the activity of mature osteoclasts, but little is known about its effect on the differentiation of mesenchymal cells towards the osteogenic lineage.
Lina M. Escobar, Zita Bendahan, Camilo Garcia, Jaime E. Castellanos   +3 more
doaj   +1 more source

Effect of rosmarinic acid on differentiation and mineralization of MC3T3-E1 osteoblastic cells on titanium surface

Animal Cells and Systems, 2021
Titanium (Ti) is a widely used biomaterial for dental implants because of its outstanding biocompatibility for hard tissues. Osseointegration, the interaction between implanted biomaterials and living cells in bone, is essential for successful ...
Moon-Jin Jeong, Do-Seon Lim, Sung Ok Kim, Cheol Park, Yung Hyun Choi, Soon-Jeong Jeong   +5 more
doaj   +1 more source

JAK2 Inhibition by Fedratinib Reduces Osteoblast Differentiation and Mineralisation of Human Mesenchymal Stem Cells

Molecules, 2021
Several signalling pathways, including the JAK/STAT signalling pathway, have been identified to regulate the differentiation of human bone marrow skeletal (mesenchymal) stem cells (hBMSCs) into bone-forming osteoblasts.
Nihal AlMuraikhi, Hanouf Alaskar, Sarah Binhamdan, Amal Alotaibi, Moustapha Kassem, Musaad Alfayez   +5 more
doaj   +1 more source

p38 MAPK Signaling in Osteoblast Differentiation [PDF]

Frontiers in Cell and Developmental Biology, 2016
The skeleton is a highly dynamic tissue whose structure relies on the balance between bone deposition and resorption. This equilibrium, which depends on osteoblast and osteoclast functions, is controlled by multiple factors that can be modulated post-translationally.
Rodríguez Carballo, Edgardo, Gamez Molina, Beatriz, Ventura Pujol, Francesc   +2 more
openaire   +4 more sources