Results 51 to 60 of about 894,587 (193)

Transcriptional program of osteoblast differentiation : coordinated activation of Notch, Wnt, and TGF-[beta] signaling pathways in MC3T3 cell line [PDF]

, 2005
In order to examine the early events in osteoblast differentiation, three different model systems for osteoblast differentiation were compared: mouse pre-osteoblastic cell line MC3T3; mouse myoblastic cell line C2C12 and primary mouse calvarial ...
Zamurovic, Natasa
core   +1 more source

Biological functions of corresponding miRNAs are involved in aging and osteoblastic differentiation.

, 2013
Biological functions of corresponding miRNAs are involved in aging and osteoblastic differentiation.
Xiaoning He (397446), Li Liao (400021), Wenkai Zhang (448765), Yan Jin (143500), Xin Fu (448766), Qing Yu (337275)   +5 more
core   +1 more source

JAK2-STAT5B pathway and osteoblast differentiation [PDF]

JAK-STAT, 2013
Osteoblast differentiation is a critical step in the maintenance of bone homeostasis. Osteoblast differentiation is generally maintained by growth hormone (GH) and various other endocrine and autocrine/paracrine factors. JAK2-STAT5B pathway is a central axis in the mechanism of GH signaling.
Darvin, Pramod, Joung, Youn Hee, Yang, Young Mok   +2 more
openaire   +2 more sources

The Roles of SNHG Family in Osteoblast Differentiation

Genes, 2022
Small nucleolar RNA host genes (SNHGs), members of long-chain noncoding RNAs (lncRNAs), have received increasing attention regarding their roles in multiple bone diseases. Studies have revealed that SNHGs display unique expression profile during osteoblast differentiation and that they could act as promising biomarkers of certain bone diseases, such as
Tan, An-Qi, Zheng, Yun-Fei
openaire   +2 more sources

Stimulation of Osteoblastic Cell Differentiation by Notch [PDF]

Journal of Bone and Mineral Research, 2002
Abstract Notch is a transmembrane protein that plays a critical role in the determination of cellular differentiation pathways. Although its importance in the development of mesenchymal tissues has been suggested, its role in skeletal tissues has not been well investigated.
Ken-Ichi, Tezuka, Masafumi, Yasuda, Naoko, Watanabe, Naoko, Morimura, Kazuki, Kuroda, Seiji, Miyatani, Nobumichi, Hozumi   +6 more
openaire   +2 more sources

Investigation of the role of the miR17-92 cluster in BMP9-induced osteoblast lineage commitment

Journal of Orthopaedic Surgery and Research, 2021
Background Bone morphogenetic protein 9 (BMP9) has been identified as a crucial inducer of osteoblastic differentiation in mesenchymal stem cells (MSCs).
Yunyuan Zhang, Xuran Jing, Zhongzhu Li, Qingwu Tian, Qing Wang, Xian Chen   +5 more
doaj   +1 more source

Effect of Menin Deletion in Early Osteoblast Lineage on the Mineralization of an In Vitro 3D Osteoid-like Dense Collagen Gel Matrix

Biomimetics, 2022
Bone has a complex microenvironment formed by an extracellular matrix (ECM) composed mainly of mineralized type I collagen fibres. Bone ECM regulates signaling pathways important in the differentiation of osteoblast-lineage cells, necessary for bone ...
Ildi Troka, Gabriele Griffanti, Lucie Canaff, Geoffrey N. Hendy, David Goltzman, Showan N. Nazhat   +5 more
doaj   +1 more source

Low magnetic field promotes recombinant human BMP-2-induced bone formation and influences orientation of trabeculae and bone marrow-derived stromal cells

Bone Reports, 2021
Effects of high magnetic fields [MFs, ≥ 1 T (T)] on osteoblastic differentiation and the orientation of cells or matrix proteins have been reported. However, the effect of low MFs (< 1 T) on the orientation of bone formation is not well known. This study
Rintaro Okada, Kai Yamato, Minoru Kawakami, Joe Kodama, Junichi Kushioka, Daisuke Tateiwa, Yuichiro Ukon, Bal Zeynep, Takuya Ishimoto, Takayoshi Nakano, Hideki Yoshikawa, Takashi Kaito   +11 more
doaj   +1 more source

Evaluation Of APC Gene Expression And Methylation Pattern Following Bone Marrow-Derived Mesenchymal Stem Cell Differentiation Into Osteoblasts Category

پیاورد سلامت, 2016
Background and Aim: Different regulation processes have an effect on osteoblastic differentiation of mesenchymal stem cells (MSCs), and among them Wnt signaling pathway is particularly desirable. In Wnt signaling pathway, Adenomatous Polyposis Coli (APC)
Raja Al-Huthaifi, Ali Dehghanifard, Saeid Kaviani, Mehrdad Noruzinia, Samira Rezaei, Mehdi Azad, Maedeh Mashhadikhan, Saeid Solali   +7 more
doaj  

miRNA-125b Regulates Osteogenic Differentiation of Periodontal Ligament Cells Through NKIRAS2/NF-κB Pathway

Cellular Physiology and Biochemistry, 2018
Background/Aims: Osteogenesis of periodontal ligament cells (PDLCS) is essential for alveolar bone repair. Varieties of factors have been found involved in the regulation of PDLCs osteoblast differentiation.
Nan Xue, Lin Qi, Guorong Zhang, Yang Zhang   +3 more
doaj   +1 more source