Results 61 to 70 of about 894,587 (193)
Indirect osteoblast differentiation by liposomal clodronate [PDF]
Journal of Cellular and Molecular Medicine, 2017 AbstractBisphosphonates impair function of osteoclasts and prevent bone resorption, the mechanism of which has been studied extensively. However, the possible effects of bisphosphonates on chondroblast differentiation and calcium deposition by osteoblasts have only been demonstrated recently.
Emi Okada +4 more
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High-phosphate Causes Endothelial Extracellular Matrix Calcification by Inducing Endothelial Cell Mesenchymal Transition and Osteoblastic Differentiation [PDF]
Chronic kidney disease (CKD) and diabetes are prevalent conditions characterized by increased cardiovascular risk, also due to vascular calcification (VC). Vascular smooth muscle cells actively participate to VC, conversely, the role of endothelial cells
Santo, Nadia +12 more
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Cell Reports, 2012 MicroRNAs (miRNAs) are essential regulators of development, physiology, and evolution, and their biogenesis is strictly controlled at multiple levels.
Michela Pasero +4 more
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Akt activation is required for TGF-β1-induced osteoblast differentiation of MC3T3-E1 pre-osteoblasts. [PDF]
PLoS ONE, 2014 BACKGROUND: We have previously reported that repeated treatment of human periodontal ligament cells and murine pre-osteoblast MC3T3-E1 cells with transforming growth factor-beta 1 (TGF-β1) inhibited their osteoblastic differentiation because of decreased
Eiichi Suzuki +6 more
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Involvement of Phosphodiesterase Isozymes in Osteoblastic Differentiation [PDF]
Journal of Bone and Mineral Research, 2002 Abstract The cyclic monophosphate nucleotides (cyclic adenosine monophosphate [cAMP] and cyclic guanosine monophosphate [cGMP]) are found ubiquitously in mammalian cells and act as second messenger transducers to effect the intracellular actions of a variety of hormones, cytokines, and neurotransmitters.
Shinji, Wakabayashi +5 more
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Gene regulatory landscape in osteoblast differentiation
Bone, 2020 The development of osteoblasts, a bone-forming cell population, occurs in conjunction with development of the skeleton, which creates our physical framework and shapes the body. In the past two decades, genetic studies have uncovered the molecular framework of this process-namely, transcriptional regulators and signaling pathways coordinate the cell ...
Hironori Hojo, Shinsuke Ohba
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, 2013 Schematic diagram of possible effects of PA and EPA on osteoblastic differentiation and calcium deposition in HASMC.
Masahiko Kurabayashi (330031) +8 more
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Involvement of nervous system on the osteoblastic differentiation and function [PDF]
, 2015 Recently the relationships between nervous system and bone metabolism have been revealed. Though recent evidences suggest that both sympathetic and sensory nerves affect bone metabolism, little is known about the involvement of neuropeptides on the ...
GOTO, Tetsuya, 後藤, 哲哉
core
Journal of Pharmacological Sciences, 2006 .: To understand the molecular pathogenesis of ossification of the posterior longitudinal ligament of the spine (OPLL), an ectopic bone formation disease, we performed cDNA microarray analysis on cultured ligament cells from OPLL patients to understand ...
Ituro Inoue, Ryuji Ikeda, So Tsukahara
doaj +1 more source
The role of osteoblast cells in the pathogenesis of unicameral bone cysts
, 2012 PurposeThe pathogenesis of unicameral bone cysts (UBCs) remains largely unknown. Osteoclasts have been implicated, but the role of osteoblastic cells has, to date, not been explored.
Tayton, Edward R +13 more
core +1 more source