Results 111 to 120 of about 222,196 (348)

Porcine placenta extract induced Akt, ERK, and JNK signaling to heighten the osteogenic activity of human osteoblasts [PDF]

open access: diamond, 2022
Worawat Songjang   +8 more
openalex   +1 more source

Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants

open access: yesAdvanced Healthcare Materials, EarlyView.
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay   +3 more
wiley   +1 more source

Bioactivity Behaviour of Osteoblasts on Commercially Pure Titanium with TiO2-ZrO2 Nanocomposite Mixture Coating

open access: yesNano Biomedicine and Engineering, 2019
This study aims to improve the bioactivity response of osteoblasts attachment and proliferation on commercial pure titanium surface by the mixture of nanocomposite coating material of 70% TiO2 (rutile 10-30 nm, Sky Spring Nanomaterials, USA) and 30% ZrO2
Thekra Ismael Hamad   +2 more
doaj   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello   +2 more
wiley   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

open access: yesAdvanced Science
As an enticing bone anabolic target, short‐term inhibition of Schnurri‐3 (SHN3) resulted in high‐bone mass due to augmented osteoblast activity. However, no studies are conducted to identify natural products targeting SHN3 inhibition. Herein, a screening
Chun‐Lan Xie   +10 more
doaj   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

open access: yesAdvanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner   +8 more
wiley   +1 more source

Influence of the Sodium Titanate Crystal Size of Biomimetic Dental Implants on Osteoblastic Behavior: An In Vitro Study

open access: yesBiomimetics
Treating the surfaces of dental implants in an alkaline medium allows us to obtain microstructures of sodium titanate crystals that favor the appearance of apatite in the physiological environment, producing osteoconductive surfaces.
Saray Fernández-Hernández   +5 more
doaj   +1 more source

The influence of nanoscale topographical cues on initial osteoblast morphology and migration [PDF]

open access: yesEuropean Cells & Materials, 2010
The natural environment of a living cell is not only organized on a micrometer, but also on a nanometer scale. Mimicking such a nanoscale topography in implantable biomaterials is critical to guide cellular behavior.
E Lamers   +6 more
doaj  

Metabolic signatures for safety assessment of low-level cadmium exposure on human osteoblast-like cells

open access: hybrid, 2020
Jinglin Tian   +7 more
openalex   +1 more source

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