Results 11 to 20 of about 222,196 (348)
Journal of Pharmacological Sciences, 2009 We analyzed the expression of 5-HT2 receptors and proteins related to inactivation of 5-HT in primary cultures of mouse osteoblasts. The mRNA for the 5-HT2A receptor was detectable in anaplastic osteoblasts as well as in differentiated and matured ...
Takao Hirai +3 more
doaj +1 more source
Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
Breast Cancer Research, 2020 Background Osteoclast activation is a hallmark of breast cancer-induced bone disease while little is known about the role of osteoblasts in this process.
Marie-Therese Haider +9 more
doaj +1 more source
Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts [PDF]
, 2019 © 2019 Published by Elsevier Inc.Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, inthe medial layer of the arteries.
Arnett, Timothy R +6 more
core +5 more sources
DKK1 Induced by 1,25D3 Is Required for the Mineralization of Osteoblasts
Cells, 2020 1α,25-dihydroxyvitamin D3 (1,25D3), the most popular drug for osteoporosis treatment, drives osteoblast differentiation and bone mineralization. Wnt/β-catenin signaling is involved in commitment and differentiation of osteoblasts, but the role ...
Sungsin Jo +9 more
doaj +1 more source
Biomedical Papers, 2015 Background: This study was aimed to investigate whether osteoblasts from diabetic patients have a promoting effect on osteogenesis of human umbilical cord mesenchymal stem cells (HUMSCs).
Ha Cheng-Zhi +9 more
doaj +1 more source
Bioengineering, 2020 There is variability in the reported effects of compounds on osteoblasts arising from differences in experimental design and choice of cell type/origin.
Robert Owen +3 more
doaj +1 more source
Bone Cell Exosomes and Emerging Strategies in Bone Engineering
Biomedicines, 2022 Bone tissue remodeling is a highly regulated process balancing bone formation and resorption through complex cellular crosstalk between resident bone and microenvironment cells.
Sanjana Vig, Maria Helena Fernandes
doaj +1 more source
Detection of early osteogenic commitment in primary cells using Raman spectroscopy [PDF]
, 2017 Major challenges in the development of novel implant surfaces for artificial joints include osteoblast heterogeneity and the lack of a simple and sensitive in vitro assay to measure early osteogenic responses.
Clarkin, C E +4 more
core +1 more source
The role of osteoblasts in regulating hematopoietic stem cell activity and tumor metastasis
Brazilian Journal of Medical and Biological Research, 2005 Bone marrow stromal cells are critical regulators of hematopoiesis. Osteoblasts are part of the stromal cell support system in bone marrow and may be derived from a common precursor.
K. Neiva, Y.-X. Sun, R.S. Taichman
doaj +1 more source
Exenatide Improves Bone Quality in a Murine Model of Genetically Inherited Type 2 Diabetes Mellitus [PDF]
, 2017 Type 2 diabetes mellitus (T2DM) is associated with skeletal complications, including an increased risk of fractures. Reduced blood supply and bone strength may contribute to this skeletal fragility.
Andreozzi +64 more
core +5 more sources