Results 101 to 110 of about 919,707 (247)

Yak milk inhibits osteoclast differentiation by suppressing TRPV5 expression

Journal of Dairy Science
: Yak milk is a potential nutrient for improving osteoporosis. However, the effect of yak milk on the expression of Ca2+ion channel TRPV5 during osteoclast differentiation is still unclear.
Torkun Mamet, Jingru Yang, Jin Zhang, Yanping Guo, Zhongkai Zhao   +4 more
doaj   +1 more source

Synchronized Cell Cycle Arrest Promotes Osteoclast Differentiation

, 2016
Osteoclast progenitors undergo cell cycle arrest before differentiation into osteoclasts, induced by exposure to macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL).
Jin-Man Kim, Kyunghee Lee, Hyun-Sook Lim, Daewon Jeong, Minsuk Kwon, Taesoo Kim, So-Young Park   +6 more
core   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

The Effect of BMP 4, 6, and 7 on Osteoclast Differentiation and Resorption [PDF]

, 2016
University of Minnesota M.S. thesis. April 2016. Major: Dentistry. Advisor: Kim Mansky. 1 computer file (PDF); v, 28 pages.Previous research by the Mansky lab has demonstrated that BMP2 enhances RANKL-mediated osteoclast differentiation and activity ...
Kar, Farnaz
core  

Differences in predominant collagen fiber orientation between dorsal and plantar trabecular bone tracts of adult mule deer calcanei suggest strain‐mode‐specific adaptation

The Anatomical Record, EarlyView.
Polarized microscopic images of the outer bone cortex (a and b) and deeper trabecular bone (c and d) of the deer calcaneus in thin cross‐sections. The brighter gray levels reflect more oblique‐to‐transverse collagen fibers in the compression/dorsal bone (a, c) and the darker gray levels reflect more longitudinal collagen in the tension/plantar bone (b,
John G. Skedros, John T. Cronin, Chad S. Mears, Brett W. Richards   +3 more
wiley   +1 more source

miRNA-340 inhibits osteoclast differentiation via repression of MITF

, 2017
Many miRNAs play critical roles in modulating various biological processes of osteoclast differentiation and function. Microphthalmia-associated transcription factor (MITF), a target of miR-340, served as pivotal transcription factor involved in ...
Hongying Zhao, Jun Zhang, Haiyu Shao, Mengran Jin, Jinping Chen, Jianwen Liu, Yazeng Huang   +6 more
core   +1 more source

Integrated microanatomy and microstructure of the maxillary tooth plate reveal a reinforced feeding system and tougher diet in Late Triassic Hyperodapedontinae (Rhynchosauria, Archosauromorpha)

The Anatomical Record, EarlyView.
Abstract Hyperodapedontine rhynchosaurs possessed a unique oral apparatus, long interpreted as an adaptation for processing abrasive and resistant plant material. However, the microanatomical and histological evidence supporting this interpretation remains poorly documented.
Caio A. Scartezini, Pedro L. B. Pruciano, Brodsky D. M. Farias, Marina B. Soares   +3 more
wiley   +1 more source

Role of cell-matrix interactions in osteoclast differentiation

, 2007
Osteoclast and their mononuclear cell precursors are present within the bone microenvironment at sites of physiologic and pathologic bone resorption. Analysis of tissues from sites of bone resorption reveal that cells expressing the full morphological ...
Flannery, M., Zhenxin Shen, Crotti, T., Shen, Z., M. R. Flannery, Tania Crotti, Steven R. Goldring, Goldring, S., Roberto Jose Fajardo, McHugh, K., Fajardo, R., Benjamin E. Bierbaum, Bierbeum, B., Kevin P. McHugh   +13 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source