Results 101 to 110 of about 38,030 (279)

Deletion of FNDC5/irisin modifies murine osteocyte function in a sex-specific manner

open access: yeseLife
Irisin, released from exercised muscle, has been shown to have beneficial effects on numerous tissues but its effects on bone are unclear. We found significant sex and genotype differences in bone from wildtype (WT) mice compared to mice lacking Fndc5 ...
Anika Shimonty   +8 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway

open access: yesBone & Joint Research
Aims: To investigate the effects of senescent osteocytes on bone homeostasis in the progress of age-related osteoporosis and explore the underlying mechanism.
Chen Yao   +7 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

A short history of dinosaurian osteocytes. [PDF]

open access: yes, 1997
Main articleA recent supposed discovery of dinosaurian osteocytes by Fukuda and Obata ( 1993) ignored earlier records from more than 20 dinosaurs, dating back 150 years. Some of the bodies they identified as osteocytes are also more likely to represent
Reid, R. E. H. (Robin)
core  

Mechanisms of palmitate-induced lipotoxicity in osteocytes [PDF]

open access: yes, 2019
Background: Lipotoxicity is defined as cellular toxicity observed in the presence of an abnormal accumulation of fat and adipocyte-derived factors in non-fat tissues.
Al Saedi, Ahmed   +4 more
core   +1 more source

Stimulation of Piezo1 by mechanical signals promotes bone anabolism

open access: yeseLife, 2019
Mechanical loading, such as caused by exercise, stimulates bone formation by osteoblasts and increases bone strength, but the mechanisms are poorly understood.
Xuehua Li   +6 more
doaj   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

Combination of autogenous dentin graft and allograft for horizontal ridge augmentation: A case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Autogenous particulate dentin has emerged as one of the promising biocompatible alternatives to traditional bone graft materials in alveolar ridge augmentation. Although its clinical success is documented, comprehensive studies combining histological and radiographic evaluations remain limited. This case report addresses this gap by
Kosuke Kashiwagi   +4 more
wiley   +1 more source

Osteocytes: Sensors of Mechanical Forces and Regulators of Bone Remodeling [PDF]

open access: yes, 2012
Osteocytes make up the largest cell population in bone and are believed to be the main mechanosensory bone cells. During mechanical disuse and overuse, osteocyte viability is compromised and is found to be co-localized with increased osteoclastic bone ...
Al-Dujaili, Saja Ali
core   +3 more sources

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