Results 11 to 20 of about 39,582 (265)

Denosumab Can Prevent Collapse in Patients with Early‐Stage Steroid‐Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy

Orthopaedic Surgery, 2023
Objective The osteoclastic bone resorption inhibitors might have positive effect in preventing femoral head collapse in patients with osteonecrosis of the femoral head (ONFH).
Bo Liu, Feng Gao, Xiaofei Xiu, Tao Wu, Zeming Liu, Bingshi Zhang, Sikai Liu, Yongtai Han   +7 more
doaj   +2 more sources

Extracellular Vesicles from BMSCs Prevent Glucocorticoid-Induced BMECs Injury by Regulating Autophagy via the PI3K/Akt/mTOR Pathway

Cells, 2022
Osteonecrosis of the femoral head (ONFH) is a common clinical disease with a high disability rate. Injury of bone microvascular endothelial cells (BMECs) caused by glucocorticoid administration is one of the important causes of ONFH, and there is ...
Jinhui Ma, Mengran Shen, Debo Yue, Weiguo Wang, Fuqiang Gao, Bailiang Wang   +5 more
doaj   +1 more source

Osteonecrosis in SLE [PDF]

Rheumatology International, 2011
To the Editor,Sayarlioglu et al. note that osteonecrosis (ON) in patientswith SLE is associated with higher doses of corticosteroids(CS) administered within 4 months as well as with totalcumulative dose [1]. The records of 868 patients with SLEfrom four centers were reviewed.
Micha Abeles, N. Rothfield, Aryeh M. Abeles, J. Urman   +3 more
openaire   +3 more sources

The changes in levels of blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1449-1455, December 2022., 2022
Abstract Objectives The extraction of a tooth exacerbates the stress in diabetic patients leading to diabetic complications so the aim was to evaluate the changes in blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction to pay special attention during a routine surgical procedure.
Zana Agani, Jehona Ahmedi, Resmije Ademi Abdyli, Mergime Prekazi Loxha, Vjosa Hamiti‐Krasniqi, Aida Rexhepi, David Stubljar   +6 more
wiley   +1 more source

High doses of zoledronic acid induce differential effects on femur and jawbone microstructure

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1487-1495, December 2022., 2022
Abstract Objectives The aim of this study is to investigate the long‐term effects on jaw and femur bone induced by oncologic doses of zoledronic acid in a young rat model. Material and Methods Six 12‐week‐old male Wistar rats received zoledronic acid (0.6 mg/kg) and six control rats received saline solution in the same volume.
Mariana Q. S. Soares, Jeroen Van Dessel, Reinhilde Jacobs, Gustavo Z. Ferreira, Paulo Sérgio da Silva Santos, Laura F. P. Nicolielo, Marco A. H. Duarte, Izabel R. F. Rubira‐Bullen   +7 more
wiley   +1 more source

As an unusual traumatic presentation, acetabular fracture and concomitant ipsilateral intertrochanteric femur fracture: a retrospective case series of 18 patients

Journal of Orthopaedic Surgery and Research, 2020
Background Acetabular fracture and concomitant ipsilateral intertrochanteric femur fracture has been suggested as an unusual traumatic presentation and rarely reported in the literature.
Bo Liu, Wenhui Ma, Sikai Liu, Xiao Chen, Mengnan Li, Jia Huo, Huijie Li, Yongtai Han   +7 more
doaj   +1 more source

Tibiofemoral rotation alignment in the normal knee joints among Chinese adults: a CT analysis

BMC Musculoskeletal Disorders, 2020
Background Consensus on tibial rotation in total knee arthroplasty (TKA) remains controversial. The present study aimed to investigate the closest anatomical reference to surgical epicondylar axis (SEA) among 10 tibial markers in Chinese adults.
Yufeng Lu, Xiaoyu Ren, Benyin Liu, Peng Xu, Yangquan Hao   +4 more
doaj   +1 more source

Osteonecrosis of the Jaw [PDF]

Journal of Oncology Practice, 2006
The paper concerns osteonecrosis of the jaw (ONJ). It is a rare but serious clinical condition. It can develop in patients treated in oncologic doses with bisphosphonates but also with denosumab. In osteoporosis ONJ seems to be very rare. Definition, pathogenesis, risk factors, prevention and treatment, and the frequency of ONJ are presented.
openaire   +5 more sources

Successful conservative management of pathological mandibular fracture resulting from chronic osteomyelitis in a 90‐year‐old woman

Oral Science International, Volume 20, Issue 1, Page 42-47, January 2023., 2023
Abstract Background We report the successful conservative management of a pathological mandibular fracture resulting from chronic osteomyelitis in a super‐elderly patient. Case Presentation A 90‐year‐old woman was admitted because of an external dental fistula with purulent drainage. Radiographs showed extensive bone destruction in the mandible.
Ryutaro Ono, Takeshi Amemiya, Toshiro Yamamoto, Narisato Kanamura   +3 more
wiley   +1 more source

Dose adductor canal block combined with local infiltration analgesia has a synergistic effect than adductor canal block alone in total knee arthroplasty: a meta-analysis and systematic review

Journal of Orthopaedic Surgery and Research, 2019
Background Both adductor canal block (ACB) and local infiltration analgesia (LIA) are effective procedures for postoperative pain control in total knee arthroplasty (TKA) without motor blockade.
Wei Zuo, Wanshou Guo, Jinhui Ma, Wei Cui
doaj   +1 more source