Results 31 to 40 of about 39,582 (265)

ALL and osteonecrosis [PDF]

Blood, 2015
In this issue of Blood, Karol et al establish a link between glutamate receptor polymorphisms and osteonecrosis, using a large discovery cohort and 2 validation cohorts. One validation cohort included patients under treatment of acute lymphoblastic leukemia (ALL) and the second is patients receiving glucocorticoid treatment of various other indications.
openaire   +3 more sources

Short-Term Efficacy and Safety of Secukinumab for Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of RCTs

Mediators of Inflammation, 2020
Secukinumab is a novel IL-17A inhibitor that has been confirmed to be effective for treating PsA and RA. Several studies have demonstrated that secukinumab also provides benefits for AS patients. Thus, we performed a meta-analysis of RCTs to evaluate the
Yu Zhou, Jinhui Ma, Juncheng Ge, Bailiang Wang, Debo Yue, Weiguo Wang   +5 more
doaj   +1 more source

Polymer Scaffolds-Enhanced Bone Regeneration in Osteonecrosis Therapy

Frontiers in Bioengineering and Biotechnology, 2021
Osteonecrosis without effective early treatment eventually leads to the collapse of the articular surface and causes arthritis. For the early stages of osteonecrosis, core decompression combined with bone grafting, is a procedure worthy of attention and ...
Hengliang Dong, Tongtong Zhu, Mingran Zhang, Dapeng Wang, Xukai Wang, Guanning Huang, Shuaishuai Wang, Minglei Zhang   +7 more
doaj   +1 more source

The pathogenesis of multifocal osteonecrosis [PDF]

Scientific Reports, 2016
AbstractOur objective was to study the incidence, etiology and diagnosis of multifocal osteonecrosis (MFON) and its treatment options to facilitate an earlier diagnosis and to optimize treatment. A radiological investigation was performed in osteonecrosis patients with a high risk of MFON for a more accurate diagnosis between January 2010 and June 2015.
Zirong Li, Zhencai Shi, Bailiang Wang, Wei Sun, Fuqiang Gao   +4 more
openaire   +2 more sources

Steroid-induced osteonecrosis

Journal of Translational Autoimmunity, 2022
Osteonecrosis associated with the use of glucocorticoids is a severe, potentially debilitating complication. In broader terms, it commonly involves the femoral head with secondary hip osteoarthritis. Osteonecrosis can also be caused by trauma and other non-traumatic factors besides steroid treatment.
Francesca Motta, Suraj Timilsina, M. Eric Gershwin, Carlo Selmi   +3 more
openaire   +3 more sources

Curculigo orchioides polysaccharides extraction, characterization, and their protective effects against femoral head necrosis

Arabian Journal of Chemistry, 2022
The use of steroid drugs such as dexamethasone in long-term treatment poses a challenge called femoral head necrosis. To reduce the destructive effects of dexamethasone, the use of herbal suppressants such as Curculigo orchioides polysaccharides (COPs ...
Baogang Zhang, Chao Lu, Zhaochen Xu, Hao Guo, Gaokui Zhang, Yangquan Hao   +5 more
doaj  

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

The relationship between apolipoprotein genes polymorphisms and susceptibility to osteonecrosis of the femoral head: a meta-analysis

Lipids in Health and Disease, 2018
Background The objective of this study was to evaluate whether apolipoprotein gene polymorphisms confer susceptibility to osteonecrosis of the femoral head (ONFH).
Yangquan Hao, Hao Guo, Zhaochen Xu, Handeng Qi, Yugui Wang, Chao Lu, Jie Liu, Puwei Yuan   +7 more
doaj   +1 more source

Current Advances of Antibacterial Biomaterials for Bone Regeneration

Advanced Materials Interfaces, EarlyView.
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong, Xue Zhang, Ying Wang, Ben Zhang   +3 more
wiley   +1 more source

Oral Ulceration With Bone Sequestration: Diagnostic Challenge, Management Strategy. [PDF]

Clin Case Rep
ABSTRACT Involving ulceration over non‐vital bone without osteonecrosis factors, Oral Ulceration with Bone Sequestration (OUBS) is underreported in the scientific and medical literature. We hope that our study will: (i) help health professionals in diagnosing and managing OUBS, (ii) encourage them to publish their experiences, and (iii) inspire ...
Dieb M, Dieb L, Robert C.
europepmc   +2 more sources