Results 31 to 40 of about 44,473 (251)

Cost-utility of adjuvant zoledronic acid in patients with breast cancer and low estrogen levels [PDF]

open access: yes, 2015
BACKGROUND: Adjuvant zoledronic acid (za) appears to improve disease-free survival (dfs) in women with early-stage breast cancer and low levels of estrogen (lle) because of induced or natural menopause.
Lamond, Nathan W D   +3 more
core   +1 more source

Meta-analysis of the potential role of extracorporeal shockwave therapy in osteonecrosis of the femoral head

open access: yesJournal of Orthopaedic Surgery and Research, 2018
Background We aimed to evaluate the role of extracorporeal shockwave therapy (ESWT) in improving osteonecrosis of the femoral head (ONFH). Methods We searched studies focusing on the role of ESWT in ONFH using PubMed, Embase, the Cochrane Library ...
Yangquan Hao   +7 more
doaj   +1 more source

A case of completed course multifocal osteonecrosis (MFON) during pregnancy due to primary antiphospholipid syndrome

open access: yesEgyptian Rheumatology and Rehabilitation, 2022
Osteonecrosis of both shoulders and hips is a rare presentation of primary antiphospholipid syndrome. A female patient aged 23 years old with no systemic diseases has her only complaint which was pain and limitations in both hips followed by both ...
Aya El Shintenawy   +3 more
doaj   +1 more source

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts [PDF]

open access: yes, 2017
Acknowledgements We sincerely thank the patients and family members who participated in this study. We would also like to thank Stefan Esher, Umeå University, for help with genealogy, and Anna Westerlund for excellent technical assistance.
Ameur, Adam   +15 more
core   +1 more source

Osteonecrosis

open access: yes, 2009
Osteonecrosis affects younger patients more often than osteoarthritis and has significantly greater long-term morbidity. Corticosteroids constitute the most common cause of nontraumatic osteonecrosis. The femoral head is the most common site of osteonecrosis. Bisphosphonate use is associated with osteonecrosis of the jaw.
Chang, Christopher   +2 more
openaire   +1 more source

Short-Term Efficacy and Safety of Secukinumab for Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of RCTs

open access: yesMediators of Inflammation, 2020
Secukinumab is a novel IL-17A inhibitor that has been confirmed to be effective for treating PsA and RA. Several studies have demonstrated that secukinumab also provides benefits for AS patients. Thus, we performed a meta-analysis of RCTs to evaluate the
Yu Zhou   +5 more
doaj   +1 more source

Polymer Scaffolds-Enhanced Bone Regeneration in Osteonecrosis Therapy

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Osteonecrosis without effective early treatment eventually leads to the collapse of the articular surface and causes arthritis. For the early stages of osteonecrosis, core decompression combined with bone grafting, is a procedure worthy of attention and ...
Hengliang Dong   +7 more
doaj   +1 more source

ALL and osteonecrosis [PDF]

open access: yesBlood, 2015
In this issue of Blood, Karol et al establish a link between glutamate receptor polymorphisms and osteonecrosis, using a large discovery cohort and 2 validation cohorts. One validation cohort included patients under treatment of acute lymphoblastic leukemia (ALL) and the second is patients receiving glucocorticoid treatment of various other indications.
openaire   +3 more sources

The pathogenesis of multifocal osteonecrosis [PDF]

open access: yesScientific Reports, 2016
AbstractOur objective was to study the incidence, etiology and diagnosis of multifocal osteonecrosis (MFON) and its treatment options to facilitate an earlier diagnosis and to optimize treatment. A radiological investigation was performed in osteonecrosis patients with a high risk of MFON for a more accurate diagnosis between January 2010 and June 2015.
Zirong Li   +4 more
openaire   +2 more sources

Steroid-induced osteonecrosis

open access: yesJournal of Translational Autoimmunity, 2022
Osteonecrosis associated with the use of glucocorticoids is a severe, potentially debilitating complication. In broader terms, it commonly involves the femoral head with secondary hip osteoarthritis. Osteonecrosis can also be caused by trauma and other non-traumatic factors besides steroid treatment.
Francesca Motta   +3 more
openaire   +3 more sources

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