Results 1 to 10 of about 23,173 (138)

Rapidly spreading Enterobacterales with OXA-48-like carbapenemases [PDF]

Journal of Clinical Microbiology
Enterobacterales (mostly Klebsiella pneumoniae, Escherichia coli) with OXA-48-like carbapenemases (e.g., OXA-48, -181, -232, -244) are undermining the global efficiency of carbapenem therapy. In the Middle East, North Africa, and some European countries,
Gisele Peirano, Johann D. D. Pitout
doaj   +4 more sources

Emergence of OXA-48-like Carbapenemase-Producing Escherichia coli in Baranya County, Hungary [PDF]

Antibiotics
Background: Carbapenem-resistant Escherichia coli (CREC) producing OXA-48-like carbapenemase was first detected in Hungary in 2022. The aim of the present study was to characterize such strains isolated in 2022–2025 in Baranya County, Hungary.
Fatma A. Mohamed, Mohamed Al-Bulushi, Szilvia Melegh, Bálint Timmer, Réka Meszéna, Csongor Freytag, Levente Laczkó, László Miló, Péter Urbán, Renáta Bőkényné-Tóth, Attila Gyenesei, Gábor Kardos, Adrienn Nyul, Edit Urbán, Tibor Pál, Ágnes Sonnevend   +15 more
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Genetic characteristics of OXA-48-producing Enterobacterales from China

Journal of Global Antimicrobial Resistance, 2021
: Objectives: In China, OXA-48-producing Enterobacterales have been identified sporadically, causing small-scale regional outbreaks. This study investigated the molecular epidemiology, transmission and evolution of OXA-48-producing Enterobacterales and ...
Lifeng Wang, Ling Guo, Kun Ye, Jiyong Yang   +3 more
doaj   +3 more sources

Detection of OXA-48-Carbapenemase-Producing Enterobacteriaceae using ChromID OXA-48 in Critical Care Patients in Egypt

Journal of Pure and Applied Microbiology, 2017
Carbapenems are a class of beta-lactam antibiotics with broad spectrum of activity. They are often considered as a last resort in treatment of infections caused by multidrug resistant organisms.
Basma A. El Awady, Mera G. Anan, Hamida A. Gohar, Mohamed H. Saleh   +3 more
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Predominance of OXA-48 carbapenemase-producing Klebsiella pneumoniae strains in tertiary hospital in Sarajevo, Bosnia and Herzegovina [PDF]

Biomolecules & Biomedicine
Klebsiella pneumoniae, a member of the Enterobacteriaceae family, demonstrates an increasing trend of resistance to carbapenems and is a common cause of both hospital- and community-acquired infections.
Amela Dedeić Ljubović, Đana Granov, Edina Zahirović, Azra Čamdžić, Adis Muhić, Irma Salimović Bešić   +5 more
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NDM-1 and OXA-48-Like Carbapenemases (OXA-48, OXA-181 and OXA-252) Co-Producing Shewanella xiamenensis from Hospital Wastewater, China

Infection and Drug Resistance, 2022
Yicheng Wen,1,* Xiaofang Xie,1,* Ping Xu,2,* Chengcheng Yang,1 Zhichen Zhu,1 Jie Zhu,1 Jingnan Lv,1 Haifang Zhang,1 Liang Chen,3,4 Hong Du1 1Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou ...
Wen Y, Xie X, Xu P, Yang C, Zhu Z, Zhu J, Lv J, Zhang H, Chen L, Du H   +9 more
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Arising Prevalence of OXA-48 producer Escherichia coli and OXA-48 with NDM co-producer Klebsiella pneumoniae Strains [PDF]

Romanian Journal of Laboratory Medicine, 2019
Background/aim: This prospective study aimed to determine the presence of the most common carbapenemase genes, blaOXA-48, blaKPC, blaIMP, blaVIM and blaNDM on carbapenem resistant clinical K.pneumoniae and E.coli isolates. Materials and methods: Isolates
Uskudar-Guclu Aylin, Guney Mustafa, Sig Ali Korhan, Kilic Selcuk, Baysallar Mehmet   +4 more
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To Be or Not to Be an OXA-48 Carbapenemase [PDF]

Microorganisms, 2022
Since the first description of OXA-48, more than forty variants have been recovered from Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as conferring similar resistance patterns, namely, the hydrolysis of carbapenems ...
Laura Dabos, Saoussen Oueslati, Sandrine Bernabeu, Rémy A. Bonnin, Laurent Dortet, Thierry Naas   +5 more
doaj   +3 more sources

Pathogenicity of Clinical OXA-48 Isolates and Impact of the OXA-48 IncL Plasmid on Virulence and Bacterial Fitness [PDF]

Frontiers in Microbiology, 2019
OXA-48 is the most common carbapenemase in Enterobacterales in Germany and one of the most frequent carbapenemases worldwide. Several reports have associated blaOXA–48 with a virulent host phenotype.
Axel Hamprecht, Julian Sommer, Matthias Willmann, Christina Brender, Yvonne Stelzer, Felix F. Krause, Tsvetan Tsvetkov, Florian Wild, Sara Riedel-Christ, Julia Kutschenreuter, Can Imirzalioglu, Aitor Gonzaga, Ulrich Nübel, Ulrich Nübel, Stephan Göttig   +14 more
doaj   +5 more sources

OXA-48-like carbapenemases in Proteus mirabilis – novel genetic environments and a challenge for detection [PDF]

Emerging Microbes and Infections
OXA-48-like enzymes represent the most frequently detected carbapenemases in Enterobacterales in Western Europe, North Africa and the Middle East. In contrast to other species, the presence of OXA-48-like in Proteus mirabilis leads to an unusually ...
Janko Sattler, Janina Noster, Yvonne Stelzer, Martina Spille, Sina Schäfer, Kyriaki Xanthopoulou, Julian Sommer, Jonathan Jantsch, Silke Peter, Stephan Göttig, Sören G. Gatermann, Axel Hamprecht   +11 more
doaj   +2 more sources