Results 91 to 100 of about 40,843 (302)
ChemistrySelect, Volume 10, Issue 38, October 13, 2025.Thioxolone derivatives are evaluated for antibacterial and anti‐diabetic potential. Compounds T‐11, T‐12, and T‐13 exhibit potent antibacterial activity against E. coli, B. cereus, and S. aureus, with low MIC values. T‐11 and T‐3 show stronger α‐glucosidase inhibition than acarbose, while molecular docking reveals T‐13 as the strongest binder ...
Thohidjhon Khajavali SK +3 more
wiley +1 more source
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017 We described herein the synthesis of novel bis-1,3,4-oxadiazole containing glycine moiety. N-{5-[5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-yl-sulfanyl]-1,3,4-oxadiazole-2-yl-methyl}-4methoxybenzamide was fully characterized by elemental analysis, FT-IR ...
I. H. R. Tomi +2 more
doaj
Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents
Molecules, 2015 New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines.
Muhammed Karabacak +6 more
doaj +1 more source
Inductive queries for a drug designing robot scientist [PDF]
, 2010 It is increasingly clear that machine learning algorithms need to be integrated in an iterative scientific discovery loop, in which data is queried repeatedly by means of inductive queries and where the computer provides guidance to the experiments that ...
A. Lingas +10 more
core +1 more source
Ketohydrazone complexes as potential emitting material in OLED [PDF]
, 2008 Ketohydrazone is a molecule that is able to act as a bidentate ligand through the O of C=O and N of N=C in the molecule. Three ketohydrazone ligands had been fully synthesized through the condensation reaction between 2- hydroxynaphthaldehydes with ...
Bahari, Haznita Rose +2 more
core
Cyclo dehydration reaction of polyhydrazides. II. Kinetic parameters obtained from isothermal thermogravimetry [PDF]
, 1988 The kinetics of the thermal conversion reaction of poly-(1,3-phenyl-1,4-phenyl)-hydrazide into poly-(1,3-phenyl-1,4-phenyl)-1,3,4-oxadiazole have been studied with isothermal thermogravimetry in continuation of a study with nonisothermal thermogravimetry
Gebben, B. +2 more
core +2 more sources
Advances in Xanthine Oxidase Inhibition: A Review of Potential Bioactive Synthetic Compounds
Archiv der Pharmazie, Volume 358, Issue 8, August 2025.This review article looks at new synthetic xanthine oxidase inhibitors discovered in the last 5 years (2025–2020). It covers an analysis of the advances, structural diversity, biological potential of the molecules investigated and future prospects in drug development.
Giorgio Antoniolli +4 more
wiley +1 more source
SEPARATION SCIENCE PLUS, Volume 8, Issue 8, August 2025.ABSTRACT Ataluren is a medication commonly used for Duchenne muscular dystrophy. Currently, it is available in granules for oral suspension. A unique reverse‐phase HPLC approach with a UV detector was established to detect and quantify ataluren and its degradation components in medicinal products. This technique utilized a phenyl hexyl stationary phase
Nagavardhana Reddy Vanga +3 more
wiley +1 more source
Synthesis of Oxadiazoles, Thiadiazoles and Triazoles Derived from Benzo[b]thiophene
Molecules, 2005 In this work 3-chloro-2-chlorocarbonylbenzo[b]thiophene (1) was prepared from cinnamic acid and then converted into the acid hydrazide 2. The azomethines 3a-e were prepared from the corresponding aryl aldehydes and the acid hydrazide 2.
N. Rezki +3 more
doaj +1 more source
Preparation of perfluorinated 1,2,4-oxadiazoles [PDF]
, 1982 Fluorinated alkyl or alkylether 1,2,4 oxadiazole compounds are prepared by cyclizing the corresponding alkyl or alkylether imidoyl amidoximes in vacuo or in an inert atmosphere at a temperature within the range of 40 C to 100 C.
Ito, T. I. +3 more
core +1 more source