Results 11 to 20 of about 12,035 (216)

BIOLOGICALLY ACTIVE OXADIAZOLE [PDF]

Journal of Drug Delivery and Therapeutics, 2015
As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are three known isomers that is 1,2,4-oxadiazole, 1,2,3-oxadiazole and 1,2,5-oxadiazole (Figure 1.0 ...
Chhama Shukla, Sanchit Srivastav
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Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives

Journal of Applied Pharmaceutical Research, 2020
1,3,4-oxadiazoles represent a class of heterocyclic five membered compounds it contain two nitrogen and one oxygen of great importance in Pharmaceutical chemistry. This nucleus show four isomeric forms 1,2,4-oxadiazole,1,3,4-oxadiazole, 1,2,5-oxadiazole,
Shailesh Pathak, Sharad Sharma, Vinay Pathak, Mahesh Prasad   +3 more
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The oxadiazole antibacterials [PDF]

Current Opinion in Microbiology, 2016
The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein. These antibacterials exhibit activity against Gram-positive bacteria, including against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE).
Jeshina, Janardhanan, Mayland, Chang, Shahriar, Mobashery   +2 more
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Therapeutic potential of oxadiazole or furadiazole containing compounds

BMC Chemistry, 2020
As we know that, Oxadiazole or furadi azole ring containing derivatives are an important class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two carbons, one oxygen atom, two nitrogen atoms, and two double bonds is known as ...
Ankit Siwach, Prabhakar Kumar Verma
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Transition metal complexes with a new tridentate ligand, 5-[6-(5-mercapto- 1,3,4-oxadiazol-2-yl)pyridin-2-yl]-1,3,4-oxadiazole-2-thiol [PDF]

Journal of the Serbian Chemical Society, 2007
A new ligand 5-[6-(5-mercapto-1,3,4-oxadiazol-2-yl)pyridin-2-yl]-1,3,4-oxadiazole- 2-thiol (L) and its Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) complexes were synthesized.
Gudasi Kalagouda, Patil Manjula, Vadavi Ramesh, Shenoy Rashmi, Patil Siddappa   +4 more
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Targeting Multiresistant Gram-Positive Bacteria by Ruthenium, Osmium, Iridium and Rhodium Half-Sandwich Type Complexes With Bidentate Monosaccharide Ligands

Frontiers in Chemistry, 2022
Bacterial resistance to antibiotics is an ever-growing problem in heathcare. We have previously identified a set of osmium(II), ruthenium(II), iridium(III) and rhodium(III) half-sandwich type complexes with bidentate monosaccharide ligands possessing ...
Bence Balázs, Zoltán Tóth, István Kacsir, István Kacsir, Adrienn Sipos, Péter Buglyó, László Somsák, Éva Bokor, Gábor Kardos, Péter Bai, Péter Bai, Péter Bai   +11 more
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Heterocyclic Compounds as Dipeptidyl Peptidase-IV Inhibitors with Special Emphasis on Oxadiazoles as Potent Anti-Diabetic Agents

Molecules, 2022
Dipeptidyl peptidase-IV (DPP-IV) inhibitors, often known as gliptins, have been used to treat type 2 diabetes mellitus (T2DM). They may be combined with other medications as an additional treatment or used alone as a monotherapy.
Badrud Duza Mohammad, Mirza Shahed Baig, Neeraj Bhandari, Falak A. Siddiqui, Sharuk L. Khan, Zubair Ahmad, Farhat S. Khan, Priti Tagde, Philippe Jeandet   +8 more
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2-Phenyl-5-(p-tolyl)-1,3,4-oxadiazole [PDF]

, 2011
Funding: University of St. Andrews and the Engineering and Physical Science Research Council (EPSRC, UK).The title compound, C15H12N2O, adopts the expected near-planar geometry, the phenyl and tolyl rings being inclined relative to the oxadiazole ring by
Woollins, J. Derek, Cordes, David B., David B. Cordes, J. Derek Woollins, Hua, Guoxiong, Alexandra M. Z. Slawin, Slawin, Alexandra M. Z., Guoxiong Hua   +7 more
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Dispersions of 1,3,4-Oxadiazole-Linked Conjugated Microporous Polymers with Carbon Nanotubes as a High-Performance Electrode for Supercapacitors

, 2022
In this study, we used classical and simple Sonogashira couplings to construct three 1,3,4-oxadiazole-linked conjugated microporous polymers (OXD-CMPs) through the reaction of 2,5-bis­(4-bromophenyl)-1,3,4-oxadiazole (OXD-Br2) as a common partner with ...
Tharwat Hassan Mansoure, Shiao-Wei Kuo, Santosh U. Sharma, Maha Mohamed Samy (10764052), Ming-Shiuan Tsai (12212974), Mohamed Gamal Mohamed, Jyh-Tsung Lee, Jung-Hui Chen (12212977), Ming-Shiuan Tsai, Mohamed Gamal Mohamed (2886701), Maha Mohamed Samy, Jyh-Tsung Lee (2355637), Santosh U. Sharma (11840450), Shiao-Wei Kuo (1468537), Jung-Hui Chen, Tharwat Hassan Mansoure (8307864)   +15 more
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Methyl-Thiol-Bridged Oxadiazole and Triazole Heterocycles as Inhibitors of NF-κB in Chronic Myelogenous Leukemia Cells

Biomedicines, 2023
Nuclear factor kappa beta (NF-κB) is a transcriptional factor that plays a crucial role in regulating cancer cell proliferation. Therefore, the inhibition of NF-κB activity by small molecules may be beneficial in cancer therapy.
Basappa Basappa, Young Yun Jung, Akshay Ravish, Zhang Xi, Ananda Swamynayaka, Mahendra Madegowda, Vijay Pandey, Peter E. Lobie, Gautam Sethi, Kwang Seok Ahn   +9 more
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