Results 21 to 30 of about 12,798 (217)
Design and Activity of Novel Oxadiazole Based Compounds That Target Poly(ADP-ribose) Polymerase
Molecules, 2022 Novel PARP inhibitors with selective mode-of-action have been approved for clinical use. Herein, oxadiazole based ligands that are predicted to target PARP-1 have been synthesized and screened for the loss of cell viability in mammary carcinoma cells ...
Divakar Vishwanath +7 more
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Green Chemistry Synthesis of Five-Membered Heterocylic Derivatives (1, 3, 4-oxadizoles) by Using Grinding Technique [PDF]
Kirkuk Journal of Science, 2018 In this research we prepared about 28 derivatives of five-membered heterocyclic compounds (1,3,4-oxadizoles) in two lines , in the first line we used phenylhydrazide and in the second line we used 4-hydroxy phenylhydrazide as starting material for ...
Nihad Taha, Eehab Rasheed
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A Review Exploring Therapeutic Effect of 1,3,4-Oxadiazole Compounds [PDF]
, 2023 There are many synthesized compounds that contain the five-membered aromatic ring 1,3,4-oxadiazole. It is advantageous for 1,3,4-oxadiazole derivatives to have effective binding with various enzymes and receptors in biological systems through numerous ...
Kurup, Shilpa S, Jat, Rakesh Kumar
core +1 more source
N-Phenyl-N-{4-[5-(4-pyridyl)-1,3,4-oxadiazol-2-yl]phenyl}aniline
Acta Crystallographica Section E, 2008 The title compound, C25H18N4O, is a non-planar bipolar ligand containing triphenylamine and 1,3,4-oxadiazole units. In the molecule, the benzene ring, the 1,3,4-oxadiazole ring, and the pyridine ring are twisted slightly with respect to each other ...
Li-Ping Han, Bin Li, Jie Liu
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SYNTHESIS,ANTIBACTERIAL ACTIVITY OF 2-AMINO 5-PHENYL -1,3,4- OXADIAZOLE DERIVATIVES
مجلة بغداد للعلوم, 2008 In the present investigation, five derivatives were synthesized as potential antimicrobial agents , The compounds are : 2-amino 5-phenyl - 1,3,4- oxadiazole dithi-ocarbomate, 2-amino 5-( 4-amino- N,N-dimethyl phenyl)- 1,3,4- oxadiazole, 2 ...
Hussain jassem Mohammed
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Molecules, 2023 Two new azaheterocycle-based bolas, such as (1-(4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl)-1H-1,2,3-triazol-4-yl)-methylenyls α,ω-bisfunctionalized PEGs, were prepared via Cu-catalyzed click reaction between 2-(4-azidophenyl)-5-(aryl)-oxadiazole-1,3,4 and ...
Mohammed S. Mohammed +9 more
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Synthesis of N, N΄3, 4-Dialkylamino-1, 2, 5-Oxadiazoles [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2003 N, N΄-3, 4-di(methylamino)-1, 2, 5-oxadiazole (1f) was prepared by dehydration of N, N΄-3, 4-di(methylamino)glyoxime (2f) in aqueous potassium hydroxid at 170-180 ˚C. Under similar conditions N, N΄-3, 4-di(benzylamino)-1, 2, 5-oxadiazole (1c) and N, N΄-3,
Ali Kakanejadifardi +2 more
doaj
, 2016 A convergent total synthesis of anhydrolycorinone is detailed, enlisting sequential intramolecular Diels−Alder reactions of a suitably substituted 2-amino-1,3,4-oxadiazole defining a novel oxadiazole → furan → benzene Diels−Alder ...
Dale L. Boger (1306542) +1 more
core +1 more source
Defence TechnologyNitramine-furoxan compounds, as a kind of energetic materials, have attracted great interest due to their outstanding detonation properties. Nevertheless, conventional molecular frameworks incorporating the 1,2,5-oxadiazole usually exhibit low thermal ...
Ziyi Xu +7 more
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2-(5-Methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenyl-1,3,4-oxadiazole
IUCrData, 2018 The asymmetric unit of the title compound, C17H13N5O, comprises four independent molecules (A–D). The respective interplanar angles between the phenyl/oxadiazole/methyltriazole/phenyl rings for the four independent molecules are A 8.8 (2), 13.0 (2), 22.5
Gamal A. El-Hiti +5 more
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