Results 31 to 40 of about 12,035 (216)
, 2021 In the current work, some 1,3,4-oxadiazole-naphthalene hybrids were designed and synthesised as VEGFR-2 inhibitors. The synthesised compounds were evaluated in vitro for their antiproliferative activity against two human cancer cell lines namely, HepG-2 ...
Ibrahim H. Eissa (10145861) +8 more
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2-(5-Methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenyl-1,3,4-oxadiazole
IUCrData, 2018 The asymmetric unit of the title compound, C17H13N5O, comprises four independent molecules (A–D). The respective interplanar angles between the phenyl/oxadiazole/methyltriazole/phenyl rings for the four independent molecules are A 8.8 (2), 13.0 (2), 22.5
Gamal A. El-Hiti +5 more
doaj +1 more source
, 2016 A convergent total synthesis of anhydrolycorinone is detailed, enlisting sequential intramolecular Diels−Alder reactions of a suitably substituted 2-amino-1,3,4-oxadiazole defining a novel oxadiazole → furan → benzene Diels−Alder ...
Dale L. Boger (1306542) +1 more
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3-[5-(Pyridin-4-yl)-1,3,4-oxadiazol-2-yl]-4H-chromen-4-one
IUCrData, 2016 In the title molecule, C16H9N3O3, the plane of oxadiazole ring is almost coplanar with attached pyridine ring and chromenyl ring system, forming dihedral angles of 2.37 (3) and 6.71 (2)°, respectively.
Dongsoo Koh
doaj +1 more source
Pharmaceuticals, 2023 Alzheimer’s disease (AD) is a progressive neurological illness that is distinguished clinically by cognitive and memory decline and adversely affects the people of old age. The treatments for this disease gained much attention and have prompted increased
Saeed Anwar +9 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 Oxadiazoles are electron-poor, five-membered aromatic heterocycles that contain one oxygen and two nitrogen atoms [...]
openaire +2 more sources
In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives
Biochemistry and Biophysics ReportsMelanoma is the most aggressive and lethal type of skin cancer, responsible for approximately 60,000 deaths annually. The main strategy for treating melanoma is surgery to completely remove the lesion and its margins.
Héverton Mendes Araújo +9 more
doaj +1 more source
, 2019 A novel aromatic diamine containing 1,3,4-oxadiazole-substituted triphenylamine (TPA) was successfully synthesized and structurally characterized.
Andra-Elena Bejan (6857759) +2 more
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, 2022 To unceasingly expand the molecular diversity of 1,3,4-oxadiazole-2-carbohydrazides, herein, small fragments (including −CH2–, −OCH2–, and −SCH2−) were incorporated into the target compounds to screen out the potential succinate dehydrogenase inhibitors (
Jian-Jun Zhu +21 more
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, 2019 A series of four 1,3,4-oxadiazole-based thermally activated delayed fluorescence (TADF) derivatives are reported as emitters for organic light emitting diodes (OLEDs).
Zhaoning Li (7449581) +9 more
core +1 more source