Results 41 to 50 of about 25,633 (260)

1,3,4-Oxadiazole N-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities

Molecules, 2021
The reaction of 5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazole-2(3H)-thione 3 with formaldehyde solution and primary aromatic amines or 1-substituted piperazines, in ethanol at room temperature yielded the corresponding N-Mannich bases 3-arylaminomethyl-5-(3,4-
L. Al-Wahaibi, A. A. Mohamed, Samar S. Tawfik, H. M. Hassan, A. El-Emam   +4 more
semanticscholar   +1 more source

Total Synthesis of Anhydrolycorinone Utilizing Sequential Intramolecular Diels−Alder Reactions of a 1,3,4-Oxadiazole

, 2016
A convergent total synthesis of anhydrolycorinone is detailed, enlisting sequential intramolecular Diels−Alder reactions of a suitably substituted 2-amino-1,3,4-oxadiazole defining a novel oxadiazole → furan → benzene Diels−Alder ...
Dale L. Boger (1306542), Scott E. Wolkenberg (1639027)   +1 more
core   +1 more source

In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives

Biochemistry and Biophysics Reports
Melanoma is the most aggressive and lethal type of skin cancer, responsible for approximately 60,000 deaths annually. The main strategy for treating melanoma is surgery to completely remove the lesion and its margins.
Héverton Mendes Araújo, Gabriel Acácio de Moura, Yasmim Mendes Rocha, Cristian Vicson Pinheiro Gomes, Valentina Nascimento e Melo de Oliveira, Ronaldo Nascimento de Oliveira, Larissa Deadame de Figueiredo Nicolete, Emanuel Paula Magalhães, Ramon R.P.P.B. de Menezes, Roberto Nicolete   +9 more
doaj   +1 more source

Synthesis, biological evaluation and docking studies of 1,2,4-oxadiazole linked 5-fluorouracil derivatives as anticancer agents

BMC Chemistry, 2021
Background 1,2,4-oxadiazole derivatives exhibited significant anti-cancer activity when they were evaluated, against human cancer cell lines. They also showed anti-inflammatory, analgesic, diabetic, immunosuppressive, α,β 3 -receptor antagonist ...
Ravi Kumar Bommera, S. Kethireddy, R. R. Govindapur, L. Eppakayala   +3 more
semanticscholar   +1 more source

n‑Type Polyimides with 1,3,4-Oxadiazole-Substituted Triphenylamine UnitsAn Innovative Structural Approach

, 2019
A novel aromatic diamine containing 1,3,4-oxadiazole-substituted triphenylamine (TPA) was successfully synthesized and structurally characterized.
Andra-Elena Bejan (6857759), Catalin-Paul Constantin (3823075), Mariana-Dana Damaceanu (2815102)   +2 more
core   +1 more source

Synthesis, Characterization, and Biologic Activity of New Acyl Hydrazides and 1,3,4-Oxadiazole Derivatives

Molecules, 2020
Starting from isoniazid and carboxylic acids as precursors, thirteen new hydrazides and 1,3,4-oxadiazoles of 2-(4-substituted-phenoxymethyl)-benzoic acids were synthesized and characterized by appropriate means. Their biological properties were evaluated
Irina Zarafu, Lilia Matei, Coralia Bleotu, Petre Ionita, Arnaud Tatibouët, Anca Păun, Ioana Nicolau, Anamaria Hanganu, Carmen Limban, Diana Camelia Nuta, Roxana Maria Nemeș, Carmen Cristina Diaconu, Cristiana Radulescu   +12 more
doaj   +1 more source

Engineering Nano-aggregates: β-Cyclodextrin Facilitates the Thiol-Gold Nanoparticle Self-Assembly [PDF]

Journal of Nanostructures, 2019
The structure and morphology of nonmaterial formed by colloidal synthesis represent a subject of interest as it is a factor deciding the physicochemical properties and biological applications of nanostructures.
D Badmapriya, Sameena Yousuf, Israel Enoch   +2 more
doaj   +1 more source

Decoupling Intrinsic Molecular Efficacy From Platform Effects: An Interpretable Machine Learning Framework for Unbiased Perovskite Passivator Discovery

Advanced Science, EarlyView.
This study establishes an interpretable machine learning framework that disentangles the intrinsic molecular efficacy of passivators from experimental platform effects—enabling unbiased, high‐throughput discovery of effective perovskite surface modifiers.
Jing Zhang, Ziyuan Li, Shan Gao, Zhen Zhu, Jing Wang, Xiangmei Duan   +5 more
wiley   +1 more source

1,3,4-Oxadiazole-based Deep Blue Thermally Activated Delayed Fluorescence Emitters for Organic Light Emitting Diodes

, 2019
A series of four 1,3,4-oxadiazole-based thermally activated delayed fluorescence (TADF) derivatives are reported as emitters for organic light emitting diodes (OLEDs).
Zhaoning Li (7449581), Emily Archer (7449584), Wei Huang (36889), Changmin Keum (7135154), Malte C. Gather (1696522), Ifor D. W. Samuel (7163057), Wenbo Li (669721), Eli Zysman-Colman (1366824), Baomin Zhao (2323384), Alexandra M. Z. Slawin (7449587)   +9 more
core   +1 more source

Design, Synthesis, and Biological Profiles of Novel 1,3,4-Oxadiazole-2-carbohydrazides with Molecular Diversity

, 2022
To unceasingly expand the molecular diversity of 1,3,4-oxadiazole-2-carbohydrazides, herein, small fragments (including −CH2–, −OCH2–, and −SCH2−) were incorporated into the target compounds to screen out the potential succinate dehydrogenase inhibitors (
Jian-Jun Zhu, Zhen-Xing Li (1553563), Pei-Yi Wang, Li-Wei Liu, Yuan-Yuan Wu, Shu-Zhen Xiang, Song Yang, Wu-Bin Shao, Jun-Rong Zhang (635679), Yuan-Yuan Wu (5269484), Xiang Zhou, Pei-Yi Wang (306058), Zhou-Qing Long (8103521), Jun-Rong Zhang, Zhou-Qing Long, Song Yang (162335), Shu-Zhen Xiang (11901676), Jian-Jun Zhu (2245093), Zhen-Xing Li, Wu-Bin Shao (4507489), Xiang Zhou (164107), Li-Wei Liu (1415464)   +21 more
core   +1 more source