Isomerization of 5-(2H-Azirin-2-yl)oxazoles: An Atom-Economic Approach to 4H-Pyrrolo[2,3-d]oxazoles
Molecules, 2021 An atom economical method for the preparation of variously substituted 4H-pyrrolo[2,3-d]oxazoles was developed on the basis of thermal isomerization of 5-(2H-azirin-2-yl)oxazoles.
Timur O. Zanakhov +4 more
doaj +1 more source
Study Of E-Smooth Support Vector Regression And Comparison With E- Support Vector Regression And Potential Support Vector Machines For Prediction For The Antitubercular Activity Of Oxazolines And Oxazoles Derivatives [PDF]
Published International Journal on Soft Computing, Artificial
Intelligence and Applications (IJSCAI), Vol.2, No.2, April 2013, 2013 A new smoothing method for solving ? -support vector regression (?-SVR), tolerating a small error in fitting a given data sets nonlinearly is proposed in this study. Which is a smooth unconstrained optimization reformulation of the traditional linear programming associated with a ?-insensitive support vector regression. We term this redeveloped problem
arxiv +1 more source
Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences [PDF]
, 2014 Biophysical studies of ligand interactions with three human telomeric repeat sequences (d(AGGG(TTAGGG)n, n = 3, 7 and 11)) show that an oxazole-based ‘click’ ligand, which induces parallel folded quadruplexes, preferentially stabilises longer telomeric ...
Alex R. O. Cousins +38 more
core +1 more source
Molecules, 2013 Aiming for the synthesis of new heterocyclic compounds containing a sulfonamido moiety suitable for use as antibacterial agents, the precursor ethyl {[4-N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenylazo}cyanoacetate was reacted with a variety of active ...
Eman A. El-Bordany +2 more
doaj +1 more source
Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage. [PDF]
, 2019 Colibactin is an assumed human gut bacterial genotoxin, whose biosynthesis is linked to the clb genomic island that has a widespread distribution in pathogenic and commensal human enterobacteria.
A Collins +64 more
core +1 more source
Molecules, 2018 C. albicans is the most frequently occurring fungal pathogen, and is becoming an increasing public health problem, especially in the context of increased microbial resistance. This opportunistic pathogen is characterized by a versatility explained mainly
Gabriel Marc +8 more
doaj +1 more source
Ultrafast electron dynamics following outer-valence ionization: The impact of low-lying relaxation satellite states [PDF]
J. Chem. Phys. 130, 154305 (2009), 2008 Low-lying relaxation satellites give rise to ultrafast electron dynamics following outer-valence ionization of a molecular system is studied. To demonstrate the impact of such satellites, the evolution of the electronic cloud after sudden removal of an electron from the highest occupied molecular orbital (HOMO) of the organic unsaturated nitroso ...
arxiv +1 more source
Journal of Organic Chemistry, 2020 A continuous flow process is presented that directly converts isoxazoles into their oxazole counterparts via a photochemical transposition reaction.
Cormac Bracken, M. Baumann
semanticscholar +1 more source
Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 The enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are primary targets in attenuating the symptoms of neurodegenerative diseases.
Ivana Šagud +8 more
semanticscholar +1 more source
The nature of the silicaphilic fluorescence of PDMPO [PDF]
, 2015 PDMPO (2-(4-pyridyl)-5-((4-(2-dimethylaminoethylaminocarbamoyl)methoxy)phenyl)oxazole), has unique silica specific fluorescence and is used in biology to understand biosilicification.
Amat +44 more
core +1 more source