Results 41 to 50 of about 24,393 (302)

Total synthesis of the post-translationally modified polyazole peptide antibiotic goadsporin [PDF]

, 2017
The structurally unique polyazole antibiotic goadsporin contains six heteroaromatic oxazole and thiazole rings integrated into a linear array of amino acids that also contains two dehydroalanine residues.
Arnison, Bagley, Bredenkamp, Connell, Davies, Doyle, Doyle, El-Faham, Haginaka, Hughes, Igarashi, Kaul, Lin, Linder, Nicolaou, Onaka, Onaka, Onaka, Onaka, Ozaki, Platzer, Wada, Wipf   +22 more
core   +2 more sources

Time-Resolved Photoelectron Spectroscopy Studies of Isoxazole and Oxazole

Journal of Physical Chemistry A, 2020
The excited state relaxation pathways of isoxazole and oxazole upon excitation with UV-light were investigated by nonadiabatic ab initio dynamics simulations and time-resolved photoelectron spectroscopy.
T. Geng, Johannes Ehrmaier, O. Schalk, Gareth W Richings, T. Hansson, G. Worth, R. Thomas   +6 more
semanticscholar   +1 more source

2-(Naphthalen-1-yl)-4-(naphthalen-1-ylmethylidene)-1,3-oxazol-5(4H)-one

Acta Crystallographica Section E, 2011
In the title compound, C24H15NO2, the oxazole ring is oriented at dihedral angles of 10.09 (4) and 6.04 (4)° with respect to the mean planes of the naphthalene ring systems, while the two naphthalene ring systems make a ...
Cevher Gündoğdu, Serap Alp, Yavuz Ergün, Barış Tercan, Tuncer Hökelek   +4 more
doaj   +1 more source

1,3-Oxazol-4-ylphosphonium salts as new non-peptide inhibitors of furin [PDF]

The Ukrainian Biochemical Journal, 2019
A series of novel triphenylphosphonium derivatives of 1,3-oxazole containing at C2 and C5-positions electron withdrawing or electron-donating groups were synthesized and characterized by 1H, 31P NMR and IR spectroscopy, element analysis and chromato-mass
T. V. Osadchuk, V. K. Kibirev1,2,, O. V. Shybyryn, A. V. Semyroz, Ye. S. Velihina, Е. R. Abdurakhmanova, V. S. Brovarets   +6 more
doaj   +1 more source

Stereoselective synthesis of hydroxylated 3-aminoazepanes using a multi-bond forming, three-step tandem process [PDF]

, 2012
A multi-bond forming, three-step tandem process involving a palladium(II)-catalysed Overman rearrangement and a ring closing metathesis reaction has been utilised for the efficient synthesis of a 2,3,6,7-tetrahydro-3-amidoazepine.
Ahmad, Ahmad, Anderson, Anderson, Anderson, Andrew Sutherland, Bernstein, Blades, Blanchette, Cant, Cardillo, Chapman, Cini, Cook, Cutri, Cutri, Delmore, Donohoe, Donohoe, Donohoe, Elhalem, Fürstner, Gilmet, Henbest, Horbal, Ireland, Jobson, Jobson, Kantorowski, Kazi, Kulanthaivel, Kurihara, Lampe, Louvel, Maier, Masse, McGonagle, Miyabe, Miyabe, Moriwake, Nicolaou, Nomura, O'Brien, Overman, Pimlott, Riber, Sajjad Ahmad, Sanford, Scholl, Schwab, Schwab, Srivastava, Stevens, Swift, Swift, Tietze, Trost, Valle, Watson, Würdemann, Yar, Yaragorla, Yet, Zaed   +63 more
core   +1 more source

Recent advances in direct C–H arylation: Methodology, selectivity and mechanism in oxazole series

Beilstein Journal of Organic Chemistry, 2011
Catalytic direct (hetero)arylation of (hetero)arenes is an attractive alternative to traditional Kumada, Stille, Negishi and Suzuki–Miyaura cross-coupling reactions, notably as it avoids the prior preparation and isolation of (hetero)arylmetals ...
Cécile Verrier, Pierrik Lassalas, Laure Théveau, Guy Quéguiner, François Trécourt, Francis Marsais, Christophe Hoarau   +6 more
doaj   +1 more source

Computational Redesign of Bacterial Biotin Carboxylase Inhibitors Using Structure-Based Virtual Screening of Combinatorial Libraries

Molecules, 2014
As the spread of antibiotic resistant bacteria steadily increases, there is an urgent need for new antibacterial agents. Because fatty acid synthesis is only used for membrane biogenesis in bacteria, the enzymes in this pathway are attractive targets for
Michal Brylinski, Grover L. Waldrop
doaj   +1 more source

The Crystal and Molecular Structure of (2Z)-2-[3-(4-Methoxybenzoyl)-4,4-dimethyl-1,2-oxazolidin-2-ylidene]-1-(4-methoxyphenyl)ethanone

Crystals, 2011
The crystal and molecular structure of the title compound, viz., (2Z)-2-[3-(4-methoxybenzoyl)-4,4-dimethyl-1,2,-oxazolidin-2-ylidene]-1-(4-methoxyphenyl)ethanone (4), is reported.
Robert A. Gossage, Alan J. Lough, Douglas G. Vaughan, Anna Petrov, Roderick C. Jones   +4 more
doaj   +1 more source

Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides. [PDF]

, 2017
A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl ...
Gu, Yang, Gu, Yucheng, Lu, Changhui, Shen, Qilong, Wu, Jiang   +4 more
core   +1 more source

Halogenated and Nonhalogenated Metabolites from the Marine-Alga-Endophytic Fungus Trichoderma asperellum cf44-2

Marine Drugs, 2018
One new bisabolane sesquiterpene, bisabolan-1,10,11-triol (1), one new norbisabolane sesquiterpene, 12-nor-11-acetoxybisabolen-3,6,7-triol (2), two new naturally occurring monoterpenes, (7S)- and (7R)-1-hydroxy-3-p-menthen-9-oic acids (3 and 4), one new ...
Yin-Ping Song, Feng-Ping Miao, Sheng-Tao Fang, Xiu-Li Yin, Nai-Yun Ji   +4 more
doaj   +1 more source