Results 81 to 90 of about 24,125 (306)

Comparative Computational Study on the Robinson–Gabriel Synthesis and Bischler–Napieralski Reaction: Density Functional Theory Investigation of T3P‐Mediated Ring Closure

European Journal of Organic Chemistry, Volume 28, Issue 21, June 3, 2025.
The detailed comparison of the Bischler–Napieralski and Robinson–Gabriel reactions of tryptamides using propylphosphonic anhydride (T3P) that leads to different products in case of a small change in the substrate is provided. The computed mechanistic pathways explain why the oxoalkyl tryptamide derivative selectively reacts in a Robinson–Gabriel ...
Patrik Pollák, Mátyás Milen, Balázs Volk, Péter Ábrányi‐Balogh   +3 more
wiley   +1 more source

Synthesis of Isoxazole- and Oxazole-4-carboxylic Acids Derivatives by Controlled Isoxazole-Azirine-Isoxazole/Oxazole Isomerization.

Journal of Organic Chemistry, 2019
The first synthesis of isoxazole-4-carboxylic acid derivatives by domino isoxazole-isoxazole isomerization is reported. Fe(II)-catalyzed isomerization of 4-acyl-5-methoxy-/5-aminoisoxazoles (dioxane, 105 °C) leads to the formation of isoxazole-4 ...
A. V. Serebryannikova, E. Galenko, M. Novikov, A. Khlebnikov   +3 more
semanticscholar   +1 more source

Poly[3-methyl-1,3-oxazolidin-2-iminium[µ₃-cyanido-tri-µ₂-cyanido-κ⁹C:N-tricuprate(I)]]

Molbank, 2021
The unexpected formation of an oxazole ring has occurred during synthesis of a copper(I) cyanide network polymer as part of our ongoing studies of the structural chemistry of these networks. Crystals of the title compound were formed during the synthesis
Leena N. Rachid, Peter W. R. Corfield
doaj   +1 more source

Multi‐trait responses in two marine diatoms to pH and irradiance reveal interactive effect of light and acidification, mediated by silicification

Limnology and Oceanography, Volume 70, Issue 5, Page 1137-1151, May 2025.
Abstract Ocean ecosystem shifts in response to anthropogenic climate change are impacting marine organisms, including phytoplankton. Ocean acidification and warming represent two key threats to marine phytoplankton, causing significant changes to the upper mixed layer of the ocean, reshuffling their distribution, and reorganizing their physiology and ...
Billy FitzGerald‐Lowry, Daniel Aagren Nielsen, Rebecca Julianne Duncan, Alyson May Theseira, Georgia Thompson, Katherina Petrou   +5 more
wiley   +1 more source

Intramolecular Pd(II)-Catalyzed Cyclization of Propargylamides: Straightforward Synthesis of 5-Oxazole-carbaldehydes [PDF]

, 2008
(Chemical Equation Presented) Direct synthesis of 2-substituted 5-oxazolecarbaldehydes was performed by intramolecular reaction of propargylamides through treatment with a catalytic amount of Pd(II) salts in the presence of a stoichiometric amount of ...
BECCALLI E. M, BORSINI E, BROGGINI G, G. PALMISANO, SOTTOCORNOLA S   +4 more
core   +1 more source

Development and validation of the method of quantification of 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide and its metabolites in laboratory animal plasma

Разработка и регистрация лекарственных средств
Introduction. The study of the systemic exposure of a new original drug is an essential part of its preclinical study. 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide is a new selective carbonic anhydrase II inhibitor for the treatment of ...
I. I. Yaichkov, M. K. Korsakov, A. A. Shetnev, N. N. Volkhin, S. S. Petukhov   +4 more
doaj   +1 more source

Synthesis of 6-Nitroderivatives of Oxazolo[3,2-a]-pyridines and Their Reactions with Nucleophiles

Molecules, 2003
5-Nitro-2-pyridone can be selectively N-phenacylated, and the resulting phenacylpyridones I undergo cyclization to 6-nitrooxazolo[3,2-a]pyridinium salts II.
Eugene V. Babaev, Alexander A. Bush
doaj   +1 more source

Characterization of a practically designed plastic scintillation plate dosimeter

Medical Physics, EarlyView.
Abstract Background Advancements in radiotherapy have enabled the use of high‐definition irradiation, leading to more precise and finely adjusted treatments in clinical settings. Nevertheless, the attainment of high resolution, an extensive measurement area, and the repeatability of dose distribution measurements persist as challenges in clinical ...
Takeshi Ohta, Yuki Nozawa, Shingo Ohira, Kanabu Nawa, Hideomi Yamashita, Keiichi Nakagawa   +5 more
wiley   +1 more source

Multicomponent Assembly of Proposed DNA Precursors in Water [PDF]

, 2012
We propose a novel pathway for the prebiotic synthesis of 2′-deoxynucleotides. Consideration of the constitutional chemical relationships between glycolaldehyde and β-mercapto-acetaldehyde, and the corresponding proteinogenic amino acids, serine and ...
Powner, Matthew W., Szostak, Jack William, Zheng, Shao-Liang   +2 more
core   +1 more source

The McKenna reaction – avoiding side reactions in phosphonate deprotection

Beilstein Journal of Organic Chemistry, 2020
The McKenna reaction is a well-known and popular method for the efficient and mild synthesis of organophosphorus acids. Bromotrimethylsilane (BTMS) is the main reagent in this reaction, which transforms dialkyl phosphonate esters into bis(trimethylsilyl ...
Katarzyna Justyna, Joanna Małolepsza, Damian Kusy, Waldemar Maniukiewicz, Katarzyna M. Błażewska   +4 more
doaj   +1 more source