N‐ to C‐Peptide Synthesis, Arguably the Future for Sustainable Production
Journal of Peptide Science, Volume 31, Issue 6, June 2025.The advent of epimerization‐free methods for coupling in N‐ to C‐direction synthesis offers improved atom economy for sustainable peptide synthesis. ABSTRACT A revolution in peptide production arrived from the innovation of carboxylate to amine C‐ to N‐direction solid‐phase synthesis.
Kinshuk Ghosh, William D. Lubell
wiley +1 more source
Synthetic and mechanistic studies of polyazole Cyclopeptide natural products: Aurantizolicin and Urukthapelstatin A [PDF]
, 2022 This PhD thesis describes the development of an effective total synthesis of the strongly cytotoxic polyazole cyclopeptide natural product aurantizolicin.
Oberheide, Ansgar
core
Evaluation of In Vitro Anti-inflammatory Activity of Azomethines of Aryl Oxazoles
E-Journal of Chemistry, 2011 Ability to inhibit erythrocyte hemolysis is often used as a characteristic of the membrane stabilising action of chemical compounds. Azomethines of aryl oxazoles were evaluated for anti-inflammatory by in vitro hemolytic membrane stabilising study.
V. Niraimathi, A. Jerad Suresh, T. Latha
doaj +1 more source
Chemical Communications, 2016 A gold-catalyzed regioselective [3+2] cycloaddition of ynamides with 1,4,2-dioxazoles was developed and offers a novel approach to obtain highly functionalized oxazoles under mild reaction conditions.
M. Chen +3 more
semanticscholar +1 more source
Discovery and In Vitro Reconstitution of Closoxazole Biosynthesis from Pyxidicoccus fallax
ChemBioChem, Volume 26, Issue 10, May 27, 2025.The myxobacterium Pyxidicoccus fallax is found to be a producer of benzoxazole‐containing natural products named closoxazoles. In vitro studies with the biosynthetic enzymes reveal new insights into the reaction mechanism for closoxazole formation.
Lucia Lernoud +4 more
wiley +1 more source
Cobalt-Catalyzed Cross-Dehydrogenative Coupling Reactions of (Benz)oxazoles with Ethers.
Journal of Organic Chemistry, 2016 The cobalt-catalyzed cross-dehydrogenative coupling of (benz)oxazoles and ethers is described. Access to some important bioactive heteroaryl ether derivatives was achieved using CoCO3 as an inexpensive catalyst at levels as low as 1.0 mol ...
Yanrong Li +5 more
semanticscholar +1 more source
Photocarboxylation of Arylated 2H‐Azirines Exploiting Continuous Flow Technology
European Journal of Organic Chemistry, Volume 28, Issue 18, May 23, 2025.An efficient continuous process for the synthesis of trisubstituted oxazoles is reported which links the photochemical opening of azirines and the subsequent trapping of the azomethine ylides with CO2 gas. This highlights challenges and solutions when incorporating CO2 as a feedstock material for the photochemical synthesis of small heterocyclic ...
Arlene Bonner +2 more
wiley +1 more source
Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD [PDF]
, 2016 Acknowledgements We thank Diamond Light Source for providing access to beamline I23. We also thank Thomas Sorensen and his staff for access to and support on beamline I02.
Bent, Andrew F +8 more
core +1 more source
European Journal of Organic Chemistry, Volume 28, Issue 17, May 21, 2025.Syntheses of quinoline and quinoxaline derivatives fused with phosphacycles were developed from commercially available quinolin‐6‐amine and quinoxalin‐6‐amine. Abstract Despite their potential in areas such as medicinal chemistry and organic materials, scaffolds in which quinoline and quinoxaline are fused to phosphacycles such as 1,3‐oxaphosphole, 1,3‐
Mohamed Ali Dridi +9 more
wiley +1 more source
The Effects of Roasting Time of Unfermented Cocoa Liquor Using the Oil Bath Methods on Physicochemical Properties and Volatile Compound Profiles [PDF]
, 2019 This study aimed to measure the effect of roasting time on physicochemical properties and volatile compounds of unfermented cocoa liquor roasted with an oil bath method.
Marseno, Djagal Wiseso +3 more
core +3 more sources