5-(Carbamoylmethylene)-oxazolidin-2-ones as a Promising Class of Heterocycles Inducing Apoptosis Triggered by Increased ROS Levels and Mitochondrial Dysfunction in Breast and Cervical Cancer [PDF]
Biomedicines, 2020 Oxazolidinones are antibiotics that inhibit protein synthesis by binding the 50S ribosomal subunit. Recently, numerous worldwide researches focused on their properties and possible involvement in cancer therapy have been conducted.
Biagio Armentano +10 more
doaj +4 more sources
Novel and Highly Efficient Carboxylative Cyclization of CO2 to 2-Oxazolidinones Using Nano-SiO2-Supported Ionic Liquid Sustainable Catalysts [PDF]
MoleculesThe conversion of CO2 into 2-oxazolidinones through carboxylative cyclization with propargylic amines is considered an effective method for utilizing waste gas as a sustainable C1 resource and mitigating the greenhouse effect.
Yulin Hu, Zongyan Tang, Xiaobing Liu
doaj +2 more sources
Comparative In Vitro Drug Susceptibility Study of Five Oxazolidinones Against Mycobacterium tuberculosis in Hainan, China [PDF]
PathogensOxazolidinones, novel synthetic antibacterials, inhibit protein biosynthesis and show potent activity against Gram-positive bacteria, including Mycobacterium tuberculosis (MTB).
Jinhui Dong +9 more
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Facile Synthesis of Oxazolidinones as Potential Antibacterial Agents [PDF]
ChemistryOpenAn efficient microwave‐assisted synthesis route for novel oxazolidinone analogues has been developed. The general synthesis of these compounds began with an L‐proline‐mediated three‐component Mannich reaction between commercially available 3‐fluoro‐4 ...
Secret P. Els +9 more
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Antibacterial Properties and Computational Insights of Potent Novel Linezolid-Based Oxazolidinones
Pharmaceuticals, 2023 The mounting evidence of bacterial resistance against commonly prescribed antibiotics warrants the development of new antibacterial drugs on an urgent basis.
M. Shaheer Malik +9 more
doaj +1 more source
Antibiotics, 2023 Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a global health concern. The propensity of MRSA to form biofilms is a significant contributor to its pathogenicity.
Audrey R. N. Ndukwe +5 more
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Efficient fabrication of oxazolidinones for the carboxylative cyclization with carbon dioxide
Journal of CO2 Utilization, 2023 Overuse of fossil energy has accelerated the development of industrialization and improved the quality of human life. However, it also leads to the excessive emission of CO2, and the greenhouse effect is threatening global climate stability and human ...
Xin Yang +5 more
doaj +1 more source
Antibiotics, 2023 Oxazolidinones are a broad-spectrum class of synthetic antibiotics that bind to the 50S ribosomal subunit of Gram-positive and Gram-negative bacteria.
McKenna E. Buckley +5 more
doaj +1 more source
Antibiotics, 2023 This study was performed to investigate the presence and characteristics of the oxazolidinone resistance genes optrA and cfr(D) in Streptococcus parasuis.
Ning Han +6 more
doaj +1 more source
Long-Term Use of Tedizolid in Osteoarticular Infections: Benefits among Oxazolidinone Drugs
Antibiotics, 2021 Background: To evaluate the efficacy and safety of long-term use of tedizolid in osteoarticular infections. Methods: Multicentric retrospective study (January 2017–March 2019) of osteoarticular infection cases treated with tedizolid.
Eva Benavent +9 more
doaj +1 more source