Results 181 to 190 of about 6,381 (215)
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Linezolid - a review of the first oxazolidinone
Expert Opinion on Pharmacotherapy, 2001Linezolid is the first of a truly new class of antibiotics, the oxazolidinones. It acts as an inhibitor of bacterial protein synthesis by blocking the formation of the 70S ribosomal initiation complex. Its activity is bacteriostatic against some species (e.g., enterococci) and bactericidal against others (e.g., pneumococci).
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Thermochemical and theoretical study of 2-oxazolidinone and 3-acetyl-2-oxazolidinone
The Journal of Chemical Thermodynamics, 2016Abstract In this paper, standard molar energies of combustion of 2-oxazolidinone and 3-acetyl-2-oxazolidinone are reported. The experimental values, obtained from static-bomb combustion calorimetry, are −(1465.42 ± 0.52) kJ·mol−1 and −(2350.86 ± 0.84) kJ·mol−1, respectively.
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Linezolid: An oxazolidinone antimicrobial agent
American Journal of Health-System Pharmacy, 2002The pharmacology, antimicrobial activity, pharmacokinetics, clinical efficacy, and adverse effects of linezolid are reviewed. Linezolid, the only oxazolidinone antimicrobial approved for use in the United States, has significant activity against gram-positive bacteria, including penicillin-, cephalosporin-, and vancomycin-resistant species.
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[Oxazolidinones and glycopeptides].
Enfermedades infecciosas y microbiologia clinica, 2003We review the chemical structure, pharmacokinetics, antimicrobial spectrum, mechanisms of action and resistance, clinical use and adverse effects of oxazolidinones (linezolid) and glycopeptides. Oxazolidinones inhibit protein synthesis and glycopeptides cell wall synthesis.
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AN UPDATE ON THE OXAZOLIDINONE ANTIBIOTICS
The Pediatric Infectious Disease Journal, 1999S M, Abdel-Rahman, G L, Kearns
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