Results 71 to 80 of about 10,637 (203)
(S)-4-Isopropyl-5,5-diphenyloxazolidin-2-one
Molbank, 2018 (S)-4-Isopropyl-5,5-diphenyloxazolidin-2-one has been synthesized for the first time by the enantiospecific oxidative carbonylation of commercially available (S)-2-amino-3-methyl-1,1-diphenylbutan-1-ol.
Raffaella Mancuso +5 more
doaj +1 more source
Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme. [PDF]
, 2016 Modifications of the bacterial ribosome regulate the function of the ribosome and modulate its susceptibility to antibiotics. By modifying a highly conserved adenosine A2503 in 23S rRNA, methylating enzyme Cfr confers resistance to a range of ribosome ...
Fujimori, Danica Galonić +3 more
core
11CO2 Fixation: A Renaissance in PET Radiochemistry [PDF]
, 2013 Carbon-11 labelled carbon dioxide is the cyclotron-generated feedstock reagent for most positron emission tomography (PET) tracers using this radionuclide.
Collier, Thomas L +6 more
core +1 more source
, 2005 Es fa un breu repàs a un seguit d'antimicrobians, analitzant els seus mecanismes d'acció i els principals mecanismes de resistència.A brief report of action mechanisms in a series of antimicrobial agents is performed, taking resistance mechanisms into ...
Santos, Carmen +2 more
core
A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia. [PDF]
, 2016 Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation.
Brandwein, Joseph +14 more
core +1 more source
Low prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy [PDF]
, 2016 Linezolid is an effective antimicrobial agent to treat methicillin-resistant Staphylococcus aureus (MRSA). Resistance to linezolid due to the cfr gene is described worldwide. The present study aimed to analyze the prevalence of the cfr-mediated linezolid
Camoez, Mariana +6 more
core +1 more source
Recent Contributions of Organic Synthesis to Forensic Science
ChemPlusChem, Volume 91, Issue 2, February 2026.Forensic science is a multidisciplinary field that plays a vital role in providing scientific evidence for criminal investigations. This review highlights advances and opportunities at the interface between organic synthesis and forensic science, with applications in drug identification, forensic toxicology, and latent fingerprint detection and ...
Gustavo dos Santos Martins +3 more
wiley +1 more source
Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Molecular reversal strategies against antibiotic resistance act through three mechanisms: inhibiting resistance gene function, blocking horizontal gene transfer, and modulating host defense. Emerging technologies, such as CRISPR‐Cas gene editing, photodynamic therapy, nanotechnology, and ecological competition, further strengthen these approaches ...
Tianjiao Li +4 more
wiley +1 more source
The Use of Oxazolidinone Products in the Treatment of Urinary Infections
Počki, 2015 The clinical efficacy of oxazolidinones with a focus on linezolid application in urinary infections is presented. High activity of the drug in methicillin-resistant Staphylococcus aureus, Enterococcus faecium and Enterococcus faecalis resistant to ...
D.D. Ivanov, Ya.O. Dombrovskyi
doaj +1 more source
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń +4 more
wiley +1 more source