Results 81 to 90 of about 10,637 (203)

The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2023–2024

open access: yesEFSA Journal, Volume 24, Issue 2, February 2026.
Abstract This report presents the main findings of the 2023–2024 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans, food‐producing animals (broilers, laying hens, fattening turkeys, fattening pigs and bovines under 1 year of age), and derived meat.
European Food Safety Authority (EFSA)   +1 more
wiley   +1 more source

Thiophenderivate als vielseitige Vorstufen für die Synthese von (Hetero)aromaten und Naturstoffen

open access: yesAngewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Verborgen, aber leistungsstark: Thiophene und ihre gesättigten Analoga haben sich als vielseitige C4‐Bausteine erwiesen, die sich effektiv in der Naturstoffsynthese sowie beim Aufbau funktionalisierter (Hetero)aromaten einsetzen lassen. Dieser Minireview soll einen Überblick über Strategien zur Anwendung dieser schwefelhaltigen heterozyklischen ...
Anna Keimer, Franz‐Lucas Haut
wiley   +1 more source

One-pot synthesis of oxazolidinones and five-membered cyclic carbonates from epoxides and chlorosulfonyl isocyanate: theoretical evidence for an asynchronous concerted pathway

open access: yesBeilstein Journal of Organic Chemistry, 2020
The one-pot reaction of chlorosulfonyl isocyanate (CSI) with epoxides having phenyl, benzyl and fused cyclic alkyl groups in different solvents under mild reaction conditions without additives and catalysts was studied.
Esra Demir   +5 more
doaj   +1 more source

Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. [PDF]

open access: yes, 2007
Linezolid, which targets the ribosome, is a new synthetic antibiotic that is used for treatment of infections caused by Gram-positive pathogens. Clinical resistance to linezolid, so far, has been developing only slowly and has involved exclusively target
Arias, Cesar A   +6 more
core   +1 more source

Safety of long-term use of linezolid: results of an open-label study

open access: yesTherapeutics and Clinical Risk Management, 2016
Jose A Vazquez,1 Anthony C Arnold,2 Robert N Swanson,3 Pinaki Biswas,3 Matteo Bassetti4 1Section of Infectious Diseases, Medical College of Georgia, Georgia Regents University, Augusta, GA, USA; 2UCLA Department of Ophthalmology, Jules Stein Eye ...
Vazquez JA   +4 more
doaj  

New Oxazolidinones for Tuberculosis: Are Novel Treatments on the Horizon?

open access: yesPharmaceutics
Multidrug-resistant tuberculosis (MDR-TB) is a global health concern. Standard treatment involves the use of linezolid, a repurposed oxazolidinone. It is associated with severe adverse effects, including myelosuppression and mitochondrial toxicity.
Ricky Hao Chen   +4 more
doaj   +1 more source

Determination Of Novel Antibacterial Triazolylmethyl Oxazolidinones Concentrations In Human Plasma By APCI-LC-MS: Application To Stability Study

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2008
Triazolylmethyl oxazolidinones are novel potent antibacterial agents recently synthesized in our laboratory. PURPOSE. Development of a rapid and specific LC-MS method for evaluating the stability of three potentially active antibacterial triazolylmethyl ...
Oludotun A. Phillips   +1 more
doaj   +1 more source

Managing the Complex Intersection Between Substance Use Disorders and Infectious Diseases

open access: yes
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 3, March 2026.
Karissa Chow   +4 more
wiley   +1 more source

Synthesis of 1,​1-​dioxobenzo[b]​thiophene-​2-​ylmethyloxycarbonyl (Bsmoc) protected N-​methyl amino acids by reduction of Bsmoc-​5-​oxazolidinones and their use in peptide synthesis [PDF]

open access: yes, 2009
The synthesis of Bsmoc-​N-​Me amino acids is presented. The first step involves p-​toluenesulfonic acid (TsOH) catalyzed condensation of a Bsmoc-​amino acid with paraformaldehyde to furnish N-​Bsmoc-​5-​oxazolidinone under MW irradn.
Gundala, Chennakrishnareddy, .   +3 more
core  

Palladium-catalyzed formation of oxazolidinones from biscarbamates: a mechanistic study

open access: yesBeilstein Journal of Organic Chemistry, 2011
Oxazolidinones can be synthesized starting from cyclic biscarbamates via a palladium-catalyzed reaction. To test the proposed mechanism of this reaction, first, bicyclonorcarene endoperoxides derived from cyano and carbomethoxy cycloheptatrienes were ...
Benan Kilbas, Metin Balci
doaj   +1 more source

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