Results 61 to 70 of about 8,892 (155)

COMPARATIVE EFFICАCY AND TOLERABILITY OF MONOTHERAPY WITH DEPAKINE CHRONOSPHERE, DRUGS OF CARBAMAZEPINE GROUP WITH EXTENDED RELEASE AND OXCARBAZEPINE IN SYMPTOMATIC AND CRYPTOGENIC FOCAL EPILEPSY (SVT. LUKA’S INSTITUTE OF CHILD NEUROLOGY AND EPILEPSY)

Русский журнал детской неврологии, 2015
Research on comparative efficаcy and tolerability of monotherapy with Depakine chronosphere, drugs of Carbamazepine group with extended release and oxcarbazepine in symptomatic and cryptogenic focal epilepsy has been conducted at Svt. Luka’s Institute of
K. Yu. Mukhin, O. A. Pylaeva, R. A. Borodin, L. N. Mukhina   +3 more
doaj   +1 more source

Epilepsy in dentatorubral–pallidoluysian atrophy: A systematic review and meta‐analysis

Epilepsia, EarlyView.
Summary of key clinical and electrophysiological characteristics of DRPLA‐related epilepsy from a systematic review and meta‐analysis of 1,191 patients. DRPLA patients with epilepsy showed earlier disease onset, longer CAG repeat expansion, and a tendency toward paternal inheritance. EEG findings frequently included photoparoxysmal responses.
Toru Horinouchi, Haruka Ishibashi, Yukako Nakagami, Yoko Kobayashi Takahashi, Takato Akiba, Masaharu Miyauchi, Naohiro Yamamoto, Ryoichi Inoue, Satoshi Kodama, Takafumi Kubota, Naoto Kuroda   +10 more
wiley   +1 more source

Association of Vitamin D Deficiency with Antiepileptic Drugs in Patients with Epilepsy

Archives of Epilepsy, 2020
Objectives:Long-term usage of antiepileptic drugs is associated with abnormal bone mineral metabolism, osteoporosis and an increased risk of fracture. The main mechanism seems to be focused on vitamin D deficiency that arises from antiepileptics.
Oya ÖZTÜRK, Elif SÖYLEMEZ, Sezin ALPAYDIN BASLO, Duygu AKSOY, Dilek ATAKLI   +4 more
doaj   +1 more source

Anti‐seizure medications in patients with post‐stroke epilepsy: A survival analysis study

Epilepsia, EarlyView.
Abstract Objective The role of antiseizure medications (ASMs) in patients with post‐stroke epilepsy (PSE) is still debated. Although a few studies have compared the efficacy of different ASMs on mortality in patients with PSE, overall evidence on the impact of ASM use on survival is limited.
Ippazio Cosimo Antonazzo, Carla Fornari, Gabriele Buongarzone, Pietro Ferrara, Giacomo Crotti, Alberto Zucchi, Paolo Angelo Cortesi, Davide Rozza, Lorenzo Giovanni Mantovani, Giampiero Mazzaglia   +9 more
wiley   +1 more source

Comparative efficacy and safety of gabapentin, pregabalin, oxcarbazepine, and duloxetine in diabetic peripheral neuropathy: A network meta-analysis

Perspectives in Clinical Research
Purpose To conduct a network meta-analysis comparing the safety and efficacy of gabapentin (GBP), pregabalin (PGB), oxcarbazepine (OXC), and duloxetine (DLX) in treating diabetic peripheral neuropathy (DPN).
Karan Bhavesh Shah, Devang A. Rana, Yash Dharmendra Mehta, Supriya Deepak Malhotra   +3 more
doaj   +1 more source

Epilepsy treatment over time: The chess game analogy for choosing, adjusting, and adding antiseizure medications

Epilepsia, EarlyView.
Abstract Recurrent seizures have such a negative impact upon the lives of persons with epilepsy that their prevention is a constant preoccupation of neurologists. Despite the large number of antiseizure medications (ASMs) currently available and of publications on their putative efficacy, adverse effects, and order of preference to start treatment ...
André Palmini, André Gus, Lecio Figueira Pinto   +2 more
wiley   +1 more source

Oxcarbazepine: Drug of the future in the treatment of trigeminal neuralgia

Journal of Indian Academy of Oral Medicine and Radiology, 2011
Background: The aim of the study was to estimate the efficacy of oxcarbazepine in trigeminal neuralgia. Oxcarbazepine is a novel antiepilepfic drug, and its effect on trigeminal neuralgia has not been studied extensively previously.
Revant H Chole, Ranjitkumar N Patil, Swati V Balsaraf, Shailesh M Gondivkar, Amol Gadbail   +4 more
doaj   +1 more source

Impact of long‐term treatment with cenobamate on concomitant usage of antiseizure medications: A real‐world retrospective study in Spain

Epilepsia, EarlyView.
Abstract Objectives This study explored the safety and effectiveness of adjunctive cenobamate (CNB) in patients with different levels of drug‐resistant epilepsy (DRE) in a real‐world setting, including its impact on the use of co‐antiseizure medication (co‐ASM). Methods This was a single‐center, retrospective, observational study.
Juan María Sánchez‐Caro, Roshan Hariramani Ramchandani, Iratxe Maestro Saiz, Juan Jesús Rodríguez Uranga   +3 more
wiley   +1 more source

Early response rates with adjunctive cenobamate in uncontrolled focal seizures: Prospective analysis of a randomized, double‐blind, placebo‐controlled study in a multinational Asian population

Epilepsia, EarlyView.
Graphical representation of article highlights, including early response rates with adjunctive cenobamate. Abstract Objective To examine early responses to cenobamate therapy using prospective data from a dose–response study in Asian patients with focal seizures (YKP3089C035, C035) that employed a titration regimen starting at 12.5 mg/day.
Kensuke Kawai, Eunyeong Choe, Louis Ferrari, Kyoung Heo, Seung Bong Hong, Huapin Huang, Koji Iida, Yong Heui Jeon, Jiwon Jung, Marc Kamin, Ji Hyun Kim, Myung Won Kim, Sang Kun Lee, Songqing Pan, Jungshin Park, Pranoti Pradhan, William E. Rosenfeld, Huiqin Xu, Takamichi Yamamoto, Sunita N. Misra   +19 more
wiley   +1 more source

Clinical trajectories and medication response in TBC1D24‐related epilepsies

Epilepsia, EarlyView.
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon, Jan H. Magielski, Bintou Bane, JoeyLynn Nolan, Sarah M. Ruggiero, Dallas Armstrong, Susan Arnold, Deepa Sirsi, Ingo Helbig, Jillian L. McKee   +9 more
wiley   +1 more source