Results 221 to 230 of about 25,431 (290)

Targeted sequencing of <i>Enterobacterales</i> bacteria using CRISPR-Cas9 enrichment and Oxford Nanopore Technologies. [PDF]

open access: yesmSystems
Cottingham H   +10 more
europepmc   +1 more source

Hidden Fungal DNA Structures May Shape Sequencing Outcomes

open access: yesBioEssays, Volume 48, Issue 6, June 2026.
Sequencing fungal DNA presents numerous challenges, and unexplored structural anomalies may be a contributor. Native ONT sequencing allows artefacts of disrupted pore translocation to be interrogated, facilitating mapping to genomic loci using raw signal analyses. Subsequent visualization tools could reveal novel genome architectures and drive advances
Paul W. Thomas
wiley   +1 more source

MiR‐21‐5p Protects Embryonic Growth and Heart Function During Developmental Hypoxia by Dampening HIF Responses and Altering Gene Expression

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
miR‐21‐5p protects embryonic growth and heart function during developmental hypoxia by dampening HIF responses and shifting gene networks toward improved cardiomyocyte survival and calcium handling. This work identifies miR‐21‐5p as a promising therapeutic target for preventing fetal growth restriction and cardiovascular impairment in high‐risk ...
Bernardo J. Krause   +12 more
wiley   +1 more source

Chloroplast Genome Insights of Gleditsia japonica var. velutina and Evolutionary Implications for Variation and Phylogeny in Gleditsia

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
This study presents the first comprehensive chloroplast genome analysis of the critically endangered G. japonica var. velutina, providing essential insights into its evolutionary divergence within the genus Gleditsia and offering a critical genomic foundation for its conservation.
Shiyu Hu   +5 more
wiley   +1 more source

Application of Oxford Nanopore Technology in Detecting Single and Multiple mtDNA Deletions

open access: yes
Mitochondrial DNA (mtDNA) plays a central role in oxidative phosphorylation, and its structural integrity is essential for normal cellular function. Due to its proximity to the respiratory chain and lack of protective histones, mtDNA is highly susceptible to variation; among these, single and multiple deletions are major contributors to mitochondrial ...
openaire   +1 more source

Home - About - Disclaimer - Privacy