Targeted sequencing of <i>Enterobacterales</i> bacteria using CRISPR-Cas9 enrichment and Oxford Nanopore Technologies. [PDF]
Cottingham H +10 more
europepmc +1 more source
Hidden Fungal DNA Structures May Shape Sequencing Outcomes
Sequencing fungal DNA presents numerous challenges, and unexplored structural anomalies may be a contributor. Native ONT sequencing allows artefacts of disrupted pore translocation to be interrogated, facilitating mapping to genomic loci using raw signal analyses. Subsequent visualization tools could reveal novel genome architectures and drive advances
Paul W. Thomas
wiley +1 more source
On the ability to extract MLVA profiles of Vibrio cholerae isolates from WGS data generated with Oxford Nanopore Technologies. [PDF]
Ambroise J +4 more
europepmc +1 more source
Challenges in Transcriptome Applications Using Oxford Nanopore Sequencing Technology
openaire +1 more source
miR‐21‐5p protects embryonic growth and heart function during developmental hypoxia by dampening HIF responses and shifting gene networks toward improved cardiomyocyte survival and calcium handling. This work identifies miR‐21‐5p as a promising therapeutic target for preventing fetal growth restriction and cardiovascular impairment in high‐risk ...
Bernardo J. Krause +12 more
wiley +1 more source
The Impact of Oxford Nanopore Technologies Based Methodologies on the Genome Sequencing and Assembly of Romanian Strains of Drosophila suzukii. [PDF]
Ratiu AC, Ionascu A, Constantin ND.
europepmc +1 more source
This study presents the first comprehensive chloroplast genome analysis of the critically endangered G. japonica var. velutina, providing essential insights into its evolutionary divergence within the genus Gleditsia and offering a critical genomic foundation for its conservation.
Shiyu Hu +5 more
wiley +1 more source
Transcriptome dataset of leaves treated with different spectra of light-emitting diodes on <i>Sandoricum koetjape</i> Merr. seedlings using cDNA-PCR sequencing with Oxford nanopore technologies. [PDF]
Defitrianida AW +6 more
europepmc +1 more source
Cancer liquid biopsies by Oxford Nanopore Technologies sequencing of cell-free DNA: from basic research to clinical applications. [PDF]
Si HQ +7 more
europepmc +1 more source
Application of Oxford Nanopore Technology in Detecting Single and Multiple mtDNA Deletions
Mitochondrial DNA (mtDNA) plays a central role in oxidative phosphorylation, and its structural integrity is essential for normal cellular function. Due to its proximity to the respiratory chain and lack of protective histones, mtDNA is highly susceptible to variation; among these, single and multiple deletions are major contributors to mitochondrial ...
openaire +1 more source

