Results 11 to 20 of about 1,121,510 (309)
Oxidative damage and defense [PDF]
The American Journal of Clinical Nutrition, 1996 Increased production of reactive oxygen species is a feature of most, if not all, human disease, including cardiovascular disease and cancer. Dietary antioxidants may be especially important in protecting against human diseases associated with free radical damage to cellular DNA, lipids, and proteins.
R A, Jacob, B J, Burri
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Oxidative Stress and Oxidative Damage in Carcinogenesis [PDF]
Toxicologic Pathology, 2009 Carcinogenesis is a multistep process involving mutation and the subsequent selective clonal expansion of the mutated cell. Chemical and physical agents including those that induce reative oxygen species can induce and/or modulate this multistep process. Several modes of action by which carcinogens induce cancer have been identified, including through
James E, Klaunig +2 more
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Evidence of Oxidative Shielding of Offspring in a Wild Mammal
Frontiers in Ecology and Evolution, 2016 Oxidative damage has been proposed as a potential mechanism underlying a life history tradeoff between survival and reproduction. However, evidence that reproduction is associated with increased oxidative damage is equivocal, and some studies have found ...
Emma I. K. Vitikainen +10 more
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Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats. [PDF]
, 2008 The development of type 2 diabetes is accompanied by decreased immune function and the mechanisms are unclear. We hypothesize that oxidative damage and mitochondrial dysfunction may play an important role in the immune dysfunction in diabetes.
Hao, Jiejie +8 more
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Antioxidants, 2015 The oxidative stress theory predicts that the accumulation of oxidative damage causes aging. More generally, oxidative damage could be a cost of reproduction that reduces survival. Both of these hypotheses have mixed empirical support.
C. Ruth Archer +7 more
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Protective Role of Sirtuin3 (SIRT3) in Oxidative Stress Mediated by Hepatitis B Virus X Protein Expression. [PDF]
PLoS ONE, 2016 The hepatitis B virus (HBV) infection is accompanied by the induction of oxidative stress, especially mediated by HBV X protein (HBx). Oxidative stress has been implicated in a series of pathological states, such as DNA damage, cell survival and ...
Ji-Hua Ren +8 more
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Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942. [PDF]
, 2020 An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage ...
Beld, Joris +9 more
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Biopolymers and Cell, 2007 Sev eral char ac ter is tics of the ba sic types of ox i da tive DNA dam age are ana lysed in the pres ent work. They are as fol lows: base and sugar mod i fi ca tions le sions, sin gle-strand and dou ble-strand breaks, apurinic/apyrimidinic sites and DNA-pro teins cross-links. The chem i cal struc ture of the most in ves ti gated types of ox i da tive
N. V. Skrypnyk, O. O. Maslova
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OXIDATIVE DAMAGE MARKERS IN ALCOHOLIC HEPATITIS
Annals of Hepatology, 2022 Introduction and objective: Alcohol hepatitis (AH) is a clinical syndrome in patients with excessive and chronic alcohol consumption. Ethanol metabolism produces free radicals: reactive oxygen species (ROS) and reactive nitrogen species (RNS).
S. Sánchez-Valle +11 more
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Elevated Level of DNA Damage and Impaired Repair of Oxidative DNA Damage in Patients with Recurrent Depressive Disorder [PDF]
, 2015 Background: Depressive disorder (DD), including recurrent DD (rDD), is a severe psychological disease, which affects a large percentage of the world population.
Bielecka-Kowalska, Anna +9 more
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