Results 31 to 40 of about 747,150 (312)

Montmorency cherries reduce the oxidative stress and inflammatory responses to repeated days high-intensity stochastic cycling

, 2014
This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing.
Stevenson, Emma, Phillip Bell, Bell, Phillip, Gareth Davison, Emma Stevenson, Howatson, Glyn, Glyn Howatson, Davison, Gareth, Walshe, Ian, Ian Walshe   +9 more
core   +1 more source

Hydrogen peroxide induced genomic instability in nucleotide excision repair-deficient lymphoblastoid cells

, 2010
Copyright @ 2010 Gopalakrishnan et al; licensee BioMed Central Ltd.Background The Nucleotide Excision Repair (NER) pathway specialises in UV-induced DNA damage repair. Inherited defects in the NER can predispose individuals to Xeroderma Pigmentosum (XP).
Gopalakrishnan, K, Kalpana Gopalakrishnan, Predrag Slijepcevic, Ting, APL, Grace Low, Low, G.K.M, Slijepcevic, P, M Prakash Hande, Hande, P, Aloysius Ting, Srikanth, P, Low, GKM, Prarthana Srikanth, Ting, A.P.L, Hande, M.P   +14 more
core   +1 more source

Linking Oxidative Stress and DNA Damage to Changes in the Expression of Extracellular Matrix Components

Frontiers in Genetics, 2021
Cells are subjected to endogenous [e.g., reactive oxygen species (ROS), replication stress] and exogenous insults (e.g., UV light, ionizing radiation, and certain chemicals), which can affect the synthesis and/or stability of different macromolecules ...
Susana G. Martins, Susana G. Martins, Rita Zilhão, Rita Zilhão, Sólveig Thorsteinsdóttir, Sólveig Thorsteinsdóttir, Ana Rita Carlos, Ana Rita Carlos   +7 more
doaj   +1 more source

Effects of hydrogen peroxide on wound healing in mice in relation to oxidative damage. [PDF]

PLoS ONE, 2012
It has been established that low concentrations of hydrogen peroxide (H(2)O(2)) are produced in wounds and is required for optimal healing. Yet at the same time, there is evidence that excessive oxidative damage is correlated with poor-healing wounds. In
Alvin Eng Kiat Loo, Yee Ting Wong, Rongjian Ho, Martin Wasser, Tiehua Du, Wee Thong Ng, Barry Halliwell   +6 more
doaj   +1 more source

Rutaecarpine Attenuates Oxidative Stress-Induced Traumatic Brain Injury and Reduces Secondary Injury via the PGK1/KEAP1/NRF2 Signaling Pathway

Frontiers in Pharmacology, 2022
The oxidative stress response caused by traumatic brain injury (TBI) leads to secondary damage in the form of tissue damage and cell death. Nuclear transcription-related factor 2 (NRF2) is a key factor in the body against oxidative stress and has an ...
Min Xu, Liu Li, Hua Liu, Wei Lu, Xiaoyang Ling, Mingjie Gong   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2 0-deoxyguanosine, in rat colonic mucosa [PDF]

, 1998
Dextran sodium sulfate (DSS) given in drinking water can induce colonic Inflammation and produce colorectal tumors in rodents, although it is not directly genotoxic.
Petit, Claude, Embvani, E., Jaeg, Jean-Philippe, Tardieu, Didier, Corpet, Denis E., Cadet, Jean   +5 more
core  

The Effects of Beverage Intake after Exhaustive Exercise on Organ Damage, Inflammation and Oxidative Stress in Healthy Males

, 2021
Strenuous exercise induces organ damage, inflammation and oxidative stress. To prevent exercise-induced organ damage, inflammation and oxidative stress, rehydrating may be an effective strategy.
Kazue Kanda, Takaki Tominaga, Wonjun Choi, Nobuhiro Nakamura, Katsuhiko Suzuki, Koichi Yada, Sihui Ma, Mayu Araya, Kaoru Sugama, Jiapeng Huang, Tsukasa Ikemura   +10 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation [PDF]

, 2012
The mitochondrial respiratory chain (MRC) consists of protein complexes I, II, III, IV and V that support oxidative phosphorylation (OXPHOS), which depends on electron transport to generate adenosine triphosphate (ATP).
Flis, Krzysztof, Skorski, Tomasz, Bhatia, Ravi, Irvine, David, Bhatia, R., Copland, Mhairi, Irvine, D., Copland, M., Skorski, T., Flis, K.   +9 more
core   +1 more source