Results 121 to 130 of about 18,352 (245)

One pot copper catalyzed conversion of oximes to thioamides [PDF]

open access: yes, 2014
Thioamides are important structural motifs found in many biologically active molecules and precursors for the synthesis of various fine chemicals, heterocycles etc.
Bose, P
core  

A Curcumin‐Derived HSP70 Inhibitor Disrupts Lysosomal Function to Suppress Triple‐Negative Breast Cancer Progression

open access: yesCell Proliferation, EarlyView.
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li   +6 more
wiley   +1 more source

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl   +6 more
wiley   +1 more source

Electronic Smoking Devices Among University Students: Usage Patterns and Chemical Composition of Inhaled Substances

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Eduard F. Valenzuela   +7 more
wiley   +1 more source

RNA Modifications: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao   +7 more
wiley   +1 more source

SÍNTESE, CARACTERIZAÇÃO E AVALIAÇÃO DA ATIVIDADE CITOTÓXICA DE COMPOSTOS CICLOPALADADOS CONTENDO COMO LIGANTES BENZALDEIDOXIMA ORTOMETALADA E ETILENOTIOURÉIA

open access: yesQuímica Nova
The halide-bridge cleavage reaction of the [Pd(C2 ,N-bzox)(µ-Cl)]2 compound (bzox = benzaldehydeoxime) with ethylenethiourea (L) in the 1:2 molar ratio at room temperature yielded the cyclopalladated compound [Pd(C2 ,N-bzox)(Cl)(L)] (1) whose replacement
Nathália A. Thomazella   +6 more
doaj   +1 more source

Protective Effect of Intracellular Compounds of Lactobacillus plantarum on Goat Sperm Quality During Cryopreservation

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Intracellular compounds from Lactobacillus plantarum were added to a goat sperm cryopreservation extender. A concentration of 20 µL/mL improved post‐thaw sperm quality, whereas higher concentrations (80–100 µL/mL) had detrimental effects. ABSTRACT Background Cryopreservation of sperm is a key strategy for preserving and transmitting the genetic traits ...
Farshad Ariyan   +3 more
wiley   +1 more source

Compound-specific Carbon Isotope Compositions of Aldehydes and Ketones in the Murchison Meteorite [PDF]

open access: yes
Compoundspecific carbon isotope analysis (13C) of meteoritic organic compounds can be used to elucidate the abiotic chemical reactions involved in their synthesis.
Aponte, Jose C.   +5 more
core   +1 more source

Aerospace Medicine and Biology: A continuing bibliography with indexes [PDF]

open access: yes
This bibliography lists 253 reports, articles, and other documents introduced into the NASA scientific and technical information system in October ...

core   +1 more source

Effects of N-alkyl quaternary quinuclidines on oxidative stress biomarkers in SH-SY5Y cells

open access: yesArhiv za Higijenu Rada i Toksikologiju
Having a broad spectrum of biological and pharmacological activities, including anticholinergic, antihistaminic, antiparasitic, antioxidant, and antitumour, quinuclidine derivatives have piqued much interest in the field of drug discovery and biomedical ...
Zandona Antonio   +4 more
doaj   +1 more source

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