Results 111 to 120 of about 10,063 (262)

A Curcumin‐Derived HSP70 Inhibitor Disrupts Lysosomal Function to Suppress Triple‐Negative Breast Cancer Progression

Cell Proliferation, EarlyView.
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li, Wanxia Wang, Yuxin Zhou, Tao Zeng, Jian Liu, Yingjie Qing, Xuan Han   +6 more
wiley   +1 more source

Manganese triacetate mediated regeneration of carbonyl compounds from oximes

, 1997
A new method for the direct conversion of oximes into aldehydes and ketones by treatment with manganese triacetate is described. Manganese triacetate can be used for an effective and mild oxidizing agent for the regeneration of carbonyl compounds from ...
Cihangir Tanyeli, Tanyeli, Cihangir, Ayhan S. Demir, DEMİR, AYHAN GÜRBÜZ, Demir, Ayhan Sıtkı, Ertan Altinel, ALTİNEL, Ertan   +6 more
core   +1 more source

Synthesis of novel penta and hexa coordinated monobutyltin(IV) derivatives based on oximes and N-protected amino acids

Main Group Metal Chemistry, 2015
Several new monobutyltin(IV) derivatives containing both oximes and N-protected amino acids have been generated. The compounds having the general formulae BuSn[(L)2A], where LH=cyclohexanoneoxime, acetophenoneoxime and (where R=-CH(CH3)2, -CH(CH3)CH2CH3,
Srivastava Manish Kumar, Maheshwari Karuna, Jain Asha, Saxena Sanjiv   +3 more
doaj   +1 more source

Nitric Oxide Tunes Secreted Metabolite Bioactivity

Molecular Microbiology, EarlyView.
Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan, Sarah L. Weisflog, Matthew Scurria, Jinyang Li, Korbinian Thalhammer, Osvaldo Gutierrez, Stuart J. Conway, Dianne K. Newman   +7 more
wiley   +1 more source

Efficacy of novel pyridinium oximes in preventing neural damage

, 2017
Organophosphates are neurotoxic compounds that inhibit acetylcholinesterase producing excess cholinergic stimulation. This produces various toxic signs including excitotoxic neuronal damage. Oximes can be used as a treatment for organophosphate poisoning
Leach, Charles Andrew
core  

Oximes of Nucleosides and Related Compounds: Synthesis, Reactions and Biological Activity

, 2018
Background: Literature data on the synthesis and structure of oximes of nucleosides and related nitrogenous bases from pyrimidine and purine were reviewed.
Edgars Abele, Ramona Abele
core   +1 more source

Experimental and Computational Elucidation of Protic Redox Reaction Mechanisms

ChemElectroChem, Volume 13, Issue 13, 2 July 2026.
Comparing quantum chemical calculations of redox potentials against experimental data provides a powerful and cost‐effective method for validating proposed protic redox reaction mechanisms, provided that computational and experimental uncertainties are robustly quantified. Molecular design of redox‐active species for applications such as redox sensing,
Lachlan O. Smith, Deborah L. Crittenden
wiley   +1 more source

Solar‐Driven Ammonia Synthesis From Nitrate Reduction Paired With CO2 Capture for Sustainable Agriculture via a Robust CuPd Heterojunction

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Laser‐assisted synthesis of CuPd amorphous/crystalline heterojunction demonstrates >80% Faradaic efficiency for nitrate‐to‐ammonia electroreduction across wide potential windows. The integrated solar‐powered electrolyzer achieves 6% solar‐to‐ammonia energy efficiency at 0.4 sun, 6–20 mg h−1 CO2 capture rate, and stability exceeding 100 h.
Weihua Guo, Xiaofeng Huang, Yangbo Ma, Yun Song, Zihao Li, Qiang Zhang, Yinger Xin, Jianjun Su, Mingming He, Ruixuan Wang, Rui Xue, Xing Li, Shibo Xi, Jian Wang, Shenlong Zhao, Siwei Zhang, Ben Zhong Tang, Alex K. Y. Jen, Ruquan Ye   +18 more
wiley   +2 more sources

Photoinduced Copper‐Catalyzed para‐Selective C–H S‐Arylation of Benzylic Oxime Carbonates with Sulfenamides

Chinese Journal of Chemistry, Volume 44, Issue 13, Page 2160-2166, 1 July 2026.
We present a dual copper/photoredox catalytic system that enables the para‐selective C–H functionalization of benzyl alcohols with sulfenamides. This approach facilitates the para‐selective C–H sulfilimination of benzylic oxime carbonates through an orchestrated sequence involving photoinduced decarboxylation/dearomatization of oxime carbonates, copper‐
Sanhua Zhang, Youcan Zhang, Jingfang Han, Ya Li, Xiao‐Feng Wu   +4 more
wiley   +1 more source

An Exploration of Vinamidinium Salts for Frame‐Shifted Synthesis

Israel Journal of Chemistry, Volume 66, Issue 4, July 2026.
Oligoheterocycles are widely used in drug discovery and materials science, where they serve as attractive alternatives to peptide fragments. There is strong interest in understanding the structural correspondence between heterocycles and amino acid motifs to recapitulate key binding elements while improving metabolic stability.
Morgan J. Cordell, Chelsey Brien, Thomas Sidarta Setio, Andrei K. Yudin   +3 more
wiley   +1 more source