Results 91 to 100 of about 5,697 (170)
Convenient and Sustainable Reduction of β‐Nitrostyrenes
A robust procedure for the synthesis of phenethylamines from the corresponding nitrostyrenes has been developed on multi‐gram scale. Using cheap reagents and green solvents the product is isolated in high yield and purity using a minimum of organic solvents without the need for chromatographic purification.
Christian B. M. Poulie +8 more
wiley +1 more source
Anatomopathological and toxicological analysis of a dog poisoned with methomyl
Abstract A dog with suspected poisoning was submitted for postmortem examination. Generalised visceral congestion was observed in the abdominal cavity, with the liver, kidneys and gastrointestinal tract most severely affected. However, there was no macroscopic evidence of granular material in the gastric contents.
André Valle de Bairros +5 more
wiley +1 more source
Post‐Synthetic Zinc Modifications to Correct Speciation in Ti‐MWW Zeolites for Catalytic Oxidation
Post‐synthetic Zn modifications of Ti‐MWW zeolite catalysts exhibit improved catalytic properties in the selective oxidation reaction, namely the ammoximation reaction. The origin of the beneficial effect of Zn is related via an array of spectroscopic and microscopic techniques to the modification of extra‐framework TiO2 and TiOx clusters and the ...
Christoph J. Kaul +10 more
wiley +2 more sources
Putative lotilaner/milbemycin‐induced Stevens‐Johnson syndrome/toxic epidermal necrolysis in a dog
Abstract Stevens‒Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, severe skin and mucocutaneous reaction, characterised by extensive epidermal necrosis and skin sloughing. Drugs are common triggers, with reactions to a number of classes reported.
Matt McHale +3 more
wiley +1 more source
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy +7 more
wiley +2 more sources
Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu +2 more
wiley +1 more source
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
A practical Pd/C‐catalyzed conversion of primary azides to nitriles was investigated under batch and continuous‐flow conditions. This transformation proceeds via net denitrogenative dehydrogenation without an external carbon source. The addition of methyl acrylate or styrene suppresses the formation of reductive byproducts, providing selective access ...
Naoya Sakurada +8 more
wiley +1 more source
Synthesis of a Novel Amine‐Based Curing Agent for Epoxy Resins Derived From Vanillin
The four‐step synthesis of a new bio‐based amine hardener is described starting from vanillin as a bio‐based compound. The hardener ADBA was utilized to cure DGEBA and the resulting T g,tanδmax was determined via DMA. Compared to other bio‐based curing agents, our curing agent is obtainable in a high yield and leads to a superior T g of 135°C ...
Bastian Hahn +3 more
wiley +1 more source
The Expanding Role of Diazirines in Synthetic Methodology
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic +3 more
wiley +1 more source

