Results 71 to 80 of about 18,352 (245)
Molecules, 2017 The ability of two newly developed oximes (K305, K307) to protect tabun-poisoned rats from tabun-induced inhibition of brain acetylcholinesterase, acute neurotoxic signs and symptoms and brain damage was compared with that of the oxime K203 and ...
Jiri Kassa +6 more
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Electrochemical Synthesis of Isoxazoles and Isoxazolines via Anodic Oxidation of Oximes
ChemElectroChem, 2023 Isoxazol(in)es are widely featured structural motifs in natural products, agrochemicals, and pharmaceuticals. The first intermolecular approach for a direct electrochemical synthesis from readily available aldoximes is reported.
Silja Hofmann +4 more
doaj +1 more source
Modifications at the C-Terminus To Improve Pyrrole−Imidazole Polyamide Activity in Cell Culture [PDF]
, 2009 Pyrrole−imidazole (Py-Im) hairpin polyamides are a class of small molecule DNA minor groove binding compounds that have been shown to modulate endogenous gene expression in cell culture.
Dervan, Peter B., Jacobs, Claire S.
core +2 more sources
Molecules, 2007 A novel and efficient method for the synthesis of N,N-dialkylamino/O-alkyl phenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes 4 using activated silica has been developed.
Mahabir P. Kaushik +2 more
doaj +1 more source
An Efficient Synthesis of Pyridoxal Oxime Derivatives under Microwave Irradiation [PDF]
, 2014 Quaternary salts of pyridoxal oxime have been synthesized by the quaternization of pyridoxal oxime with substituted phenacyl bromides using microwave heating.
Bušić, Valentina +3 more
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Steroidal Oximes and Cervical Cancer: An In Silico Mechanistic Pathway Approach
Scientia PharmaceuticaCervical cancer affects 661,000 women worldwide; as a result, new treatment alternatives are still being sought, with steroid oximes being the most prominent.
Carlos Antonio Sánchez-Valdeolivar +4 more
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Acta Medica, 2001 1. The influence of anticholinergic drugs (atropine, benactyzine, biperiden) on the efficacy of monopyridinium and bispyridinium oximes (HI-6, BI-6, obidoxime, pralidoxime, methoxime) on soman-induced supralethal poisoning was studied in mice. 2.
Jiří Kassa
doaj +1 more source
Erythromycin a oxime 11,12-carbonate and its oxime ethers.
The Journal of Antibiotics, 1989 Erythromycin A oxime 11,12-carbonate (5a) and its oxime ethers 5b approximately 5p have been prepared and their antibacterial activities compared with those of erythromycin A (1) and its 11,12-carbonate 2. The oxime 5a and many of its oxime ether derivatives showed good activity in vitro against Gram-positive and the more permeable Gram-negative ...
E G, Brain +4 more
openaire +3 more sources
BiomoleculesNew furan, thiophene, and triazole oximes were synthesized through several-step reaction paths to investigate their potential for the development of central nervous systems (CNS)-active and cholinesterase-targeted therapeutics in organophosphorus ...
Milena Mlakić +4 more
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Self injection of Dichlorvos, an Organophosphorus Compound [PDF]
, 2008 We report two patients who injected themselves a strong organophosphate compound, dichlorvas, and showed the typical clinical picture of organophosphate intoxication. There are very few case reports of parenteral organophosphorous poisoning.
DM, Mahesh +4 more
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