Results 61 to 70 of about 10,063 (262)

In Silico Identification of Hit Compound to Counteract A-Series Nerve Agents Poisoning

Chemistry
Organophosphorus (OP) nerve agents inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) by phosphylating the catalytic serine. Oxime reactivators can restore enzymatic activity by a nucleophilic attack of the oximate anion on the ...
Nikola Maraković
doaj   +1 more source

Conversion of Oximes to Carbonyl Compounds by Triscetylpyridinium Tetrakis(oxodiperoxotungsto) Phosphate (PCWP)-mediated Oxidation with Hydrogen Peroxide

Molecules, 2008
Aromatic and aliphatic oximes have been deoximated in chloroform-water to the corresponding aldehydes with dilute hydrogen peroxide and triscetylpyridinium tetrakis (oxodiperoxotungsto) phosphate as catalyst.
Rosa M. Toscano, Gaetano Tomaselli, Antonio Rescifina, Ugo Chiacchio, Francesco P. Ballistreri   +4 more
doaj   +1 more source

Organophosphorus compounds and oximes: a critical review

, 2020
Organophosphorus (OP) pesticides and nerve agents still pose a threat to the population. Treatment of OP poisoning is an ongoing challenge and burden for medical services.
Wille, Timo, Worek, Franz, Thiermann, Horst   +2 more
core   +1 more source

Novel and Efficient Synthesis of N,N-dialkylamino-O-alkyl-2-(1-methyl-2-oxopropylidene)phosphorohydrazido Oximes. Part 3.

Molecules, 2007
A novel and efficient method has been developed for the synthesis of N,N-dialkylamino-O-alkyl-2-(1-methyl-2-oxopropylidene)phosphorohydrazido oximes 5.
Mahabir P. Kaushik, Arvind K. Gupta, Rajesh Kumar   +2 more
doaj   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, EarlyView.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Evaluation of the activity of aromatic aldehydes and their oximes against human erythrocyte acetylcholinesterase enzyme

Acta Brasiliensis, 2017
Considering the therapeutic importance of the acetylcholinesterase inhibitor drugs, as well, enzyme regenerators drugs, in cases of organophosphate poisoning.
Maíra Dias Mangueira Bastos, Victória Laysna dos Anjos Santos, Arlan de Assis Gonsalves, Cleônia Roberta Melo Araújo   +3 more
doaj   +1 more source

Antidotal effect of combinations obidoxime/HI-6 and memantine in mice poisoned with soman, dichlorvos or heptenophos [PDF]

Vojnosanitetski Pregled, 2011
Introduction/Aim. In acute organophosphate poisoning the issue of special concern is the appearance of muscle fasciculations and convulsions that cannot be adequately antagonised by the use of atropine and oxime therapy.
Antonijević Biljana, Stojiljković Miloš P., Bokonjić Dubravko, Vučinić Slavica   +3 more
doaj   +1 more source

Synthesis, Characterization and Preliminary Antifungal Activity of Some Co(II) and Zn(II) Complexes Derived from Oximes of 2-Acetyl Aromatic Heterocycles

Orbital: The Electronic Journal of Chemistry, 2021
Present work focuses on syntheses, characterization, preliminary antifungal screening of some transition metal complexes derived from oximes of 2-acetylpyridine, 2-acetylthiophene and 2-acetylfuran; using Zn(II) and Co(II) chlorides.
Deepankar Sharma, Purnima Nag
doaj   +1 more source

Novel and Efficient Synthesis of N,N-Dialkylaminoand O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) Phosphonohydrazido Oximes - Potential Marine Fish Toxin Analogues. Part 2

Molecules, 2007
A novel and efficient method for the synthesis of N,N-dialkylamino/O-alkyl phenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes 4 using activated silica has been developed.
Mahabir P. Kaushik, Arvind K. Gupta, Rajesh Kumar   +2 more
doaj   +1 more source

Electrochemical Synthesis of Isoxazoles and Isoxazolines via Anodic Oxidation of Oximes

ChemElectroChem, 2023
Isoxazol(in)es are widely featured structural motifs in natural products, agrochemicals, and pharmaceuticals. The first intermolecular approach for a direct electrochemical synthesis from readily available aldoximes is reported.
Silja Hofmann, Johannes Winter, Tobias Prenzel, Dr. María deJesús Gálvez‐Vázquez, Prof. Dr. Siegfried R. Waldvogel   +4 more
doaj   +1 more source