Results 41 to 50 of about 18,352 (245)

Novel chemoenzymatic oxidation of amines into oximes based on hydrolase-catalysed peracid formation [PDF]

, 2017
The efficient transformation of benzylamines into the corresponding oximes has been described by means of a chemoenzymatic process.
Gotor Fernández, Vicente, Gotor Santamaría, Vicente Miguel, Lavandera García, Iván, Méndez Sánchez, Daniel   +3 more
core   +2 more sources

Biocatalytic Synthesis of Isoxazolines Enabled by Cryptic Nitrile Oxide Formation by a Vanadium‐Dependent Chloroperoxidase

Angewandte Chemie, EarlyView.
The vanadium‐dependent haloperoxidase (VHPO) class of enzymes has been shown to catalyze cryptic nitrile oxide generation in an oxidative [3+2] cycloaddition reaction between aldoximes and alkenes to generate isoxazolines. This biotechnology has been applied to a chemoenzymatic sequence starting from aldehydes through in situ condensation with ...
Manik Sharma, Kyle F. Biegasiewicz
wiley   +2 more sources

A Comparison of the Neuroprotective Efficacy of Newly Developed Oximes (K156, K203) and Currently Available Oximes (Obidoxime, HI-6) in Cyclosarin-poisoned Rats

Acta Medica, 2008
The neuroprotective effects of newly developed oximes (K156, K203) and currently available oximes (obidoxime, HI-6) in combination with atropine in rats poisoned with cyclosarin were studied.
Jiří Kassa, Jana Žďárová Karasová, Sandra Tesařová, Kamil Kuča, Kamil Musílek   +4 more
doaj   +1 more source

Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase

Biomolecules, 2021
Poisoning with organophosphorus compounds used as pesticides or misused as chemical weapons remains a serious threat to human health and life.
Jakub Jończyk, Jędrzej Kukułowicz, Kamil Łątka, Barbara Malawska, Young-Sik Jung, Kamil Musilek, Marek Bajda   +6 more
doaj   +1 more source

Mixed‐Functionalized Acylgermanes Result in Wavelength‐Controlled Fragmentation

Angewandte Chemie, EarlyView.
Selective radical generation from PEG‐acylgermanes is achieved by controlling the used wavelength. Distinct aryl‐carbonyl units undergo wavelength‐dependent α‐cleavage, producing radicals with different reactivities. UV/Vis, TD‐DFT, and photo‐CIDNP spectroscopy confirm that small adjustments in light input directly dictate radical identity and ...
André Culum, Manfred Drusgala, Roland C. Fischer, Anne‐Marie Kelterer, Mario Leypold, Dmytro Neshchadin, Michael Haas   +6 more
wiley   +2 more sources

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, EarlyView.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

Sulfunic Acid Modifired MCM-41 Mesoporous Silica as an Efficient Nano-Catalyst for Synthesis of amides and lactams from Oximes Via Beckman Rearrangement [PDF]

Journal of Sciences, Islamic Republic of Iran, 2016
Mesoporous MCM-41 silicas anchored with sulfonic acid (–SO3H) groups (denoted MSN-SA) via postsynthesis modification are very effective for the Beckman rearrangement.
S. Eskandari, E. Tarizade, F. Teymouri
doaj  

Solar‐Driven Ammonia Synthesis From Nitrate Reduction Paired With CO2 Capture for Sustainable Agriculture via a Robust CuPd Heterojunction

Angewandte Chemie, EarlyView.
Laser‐assisted synthesis of CuPd amorphous/crystalline heterojunction demonstrates >80% Faradaic efficiency for nitrate‐to‐ammonia electroreduction across wide potential windows. The integrated solar‐powered electrolyzer achieves 6% solar‐to‐ammonia energy efficiency at 0.4 sun, 6–20 mg h−1 CO2 capture rate, and stability exceeding 100 h.
Weihua Guo, Xiaofeng Huang, Yangbo Ma, Yun Song, Zihao Li, Qiang Zhang, Yinger Xin, Jianjun Su, Mingming He, Ruixuan Wang, Rui Xue, Xing Li, Shibo Xi, Jian Wang, Shenlong Zhao, Siwei Zhang, Ben Zhong Tang, Alex K. Y. Jen, Ruquan Ye   +18 more
wiley   +2 more sources

Convergent Valorization via Scalable C═N Bond Electrosynthesis Through Metal‐Dopant Interfacial Engineering in a Flow Electrolyzer

Angewandte Chemie, EarlyView.
This study establishes an innovative approach to synthesize organonitrogens featuring C═N bonds efficiently using non‐precious metal‐doped MoS2 in a flow electrolyzer. Fe dopant significantly enhances Faradaic efficiency and yield rate, achieving over 81% and 2630 mmol h−1 g−1 for formaldoxime production. This platform upcycles pollutants into valuable
Ruijie Yi, Jiu Chen, Xiaoyong Mo, Tian Zeng, Jingtao Zhou, Fulai Liu, Shu‐Chih Haw, Yong Chen, Ruosong Li, Edmund C. M. Tse   +9 more
wiley   +2 more sources

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source