Results 31 to 40 of about 18,352 (245)

Silver and platinum-catalysed addition of O–H and N–H bonds to allenes [PDF]

open access: yes, 2014
Transition-metal catalysed nucleophile addition to allenes is a very powerful tool for the synthesis of functionalised molecules containing heteroatoms, heterocycles in the intramolecular version, or allyl derivatives in the intermolecular version.
Munoz-Herranz, Maria
core   +1 more source

Salicylaldehyde hydrazones: buttressing of outer sphere hydrogen-bonding and copper-extraction properties [PDF]

open access: yes, 2017
Salicylaldehyde hydrazones are weaker copper extractants than their oxime derivatives, which are used in hydrometallurgical processes to recover ~20 % of the world’s copper.
Bauer, Heiko   +7 more
core   +1 more source

Reactivation Potency of New Group of Acetylcholinesterase Reactivators and Their Comparison with Currently Available Oximes

open access: yesActa Medica, 2006
In this work, in vitro potency of novel serie of monoquaternary pyridinium oximes to reactivate cyclosarin-inhibited acetylcholinesterase (AChE) was tested.
Kamil Kuča, Jan Pícha, Daniel Jun
doaj   +1 more source

PHOSPHORYLPHOSPHATASE AND OXIMES [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1961
The effects of pralidoxime iodide, 1,1‐trimethylenebis(4‐formylpyridinium bromide) dioxime and diacetyl monoxime on the activity of phosphorylphosphatase prepared from pig kidney in vitro have been studied. It was found that these oximes, even at high concentrations, did not affect the activity of the enzyme.
H, EDERY, G, SCHATZBERG-PORATH
openaire   +2 more sources

EDA Complex-Mediated C(sp<sup>3</sup>)-H Cross-Dehydrogenative Coupling Enables Synthesis of Noncanonical <i>α</i>,<i>β</i>-Diamino Acids. [PDF]

open access: yesEuropean J Org Chem
Access to nonproteinogenic α,β‐diamino acids from simple feedstock precursors is of great interest to generate medicinal small molecule libraries. We report a regioselective photoinduced C(sp3)–C(sp3) cross‐dehydrogenative coupling (CDC) of N‐arylglycine derivatives with amides.
Sachidanandan K   +4 more
europepmc   +2 more sources

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

open access: yes, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L   +6 more
core   +1 more source

Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX

open access: yesNeurobiology of Disease, 2020
A novel oxime platform, the substituted phenoxyalkyl pyridinium oximes (US patent 9,227,937), was invented at Mississippi State University with an objective of discovering a brain-penetrating antidote to highly potent organophosphate anticholinesterases,
Janice E. Chambers, Edward C. Meek
doaj   +1 more source

The Synthesis of Novel aza-Steroids and α, β-Unsaturated-Cyanoketone from Diosgenin

open access: yesMolecules, 2023
Recent studies have demonstrated the antiproliferative and cytotoxic effects of aza-steroids and steroidal sapogenins on human cancer cell lines. The scientific community has shown a growing interest in these compounds as drug candidates for cancer ...
Dayana Mesa   +9 more
doaj   +1 more source

Pharmacokinetic Studies on Oximes in Organophosphate Poisoning: A Mini Review [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Organophosphate (OP) poisoning is one of the most common causes of poisoning in developing countries especially in Southeastern Asia. Poisoning with phosphorus-containing organic chemicals or OP compounds can be managed with antidotes like oximes which ...
Girish Thunga   +6 more
doaj  

One-Pot Synthesis of Dioxime Oxalates

open access: yesMolbank, 2022
Dioxime oxalates, a type of carbonyl oximes, are well-known as clean sources of iminyl radicals that undergo key organic chemistry transformations. A series of dioxime oxalates is reported in this manuscript, obtained by the reaction of the corresponding
Laura Adarve-Cardona   +3 more
doaj   +1 more source

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