Results 11 to 20 of about 5,697 (170)
Metal-free sustainable synthesis of oximes and hydrazones from benzyl alcohol and benzylamine [PDF]
Herein, we report a one-pot synthesis of oximes and hydrazones via oxidative coupling of alcohols and amines with hydroxylamine hydrochloride and hydrazine, mediated by N-bromosuccinimide (NBS) and phenyliodine(iii) diacetate (PIDA), respectively.
Rupali B. Devgunde +3 more
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Three carbonyl-containing extracts of essential oils from Eucalyptus citriodora (Myrtaceae), Cymbopogon citratus (Gramineae) and Lippia multiflora (Verbenaceae) were used for the preparation of oximes.
Igor W. Ouédraogo +4 more
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1. The therapeutic efficacy of various oximes (pralidoxime, obidoxime, methoxime, HI-6, HLö-7, BI-6) against supralethal nerve agent poisoning (soman, sarin, cyclosin) in mice was tested. 2. New oxime BI-6, synthesized in our laboratory, is significantly
Jiří Kassa
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Amidoximes and Oximes: Synthesis, Structure, and Their Key Role as NO Donors
Nitric oxide (NO) is naturally synthesized in the human body and presents many beneficial biological effects; in particular on the cardiovascular system.
Tanya Sahyoun +2 more
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The ability of newly developed oximes (K347, K628) to reduce tabun-induced acute neurotoxic signs and symptoms was compared with currently available oximes (obidoxime, HI-6) using a functional observational battery.
Jiří Kassa +4 more
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In this work, in vitro potency of novel serie of monoquaternary pyridinium oximes to reactivate cyclosarin-inhibited acetylcholinesterase (AChE) was tested.
Kamil Kuča, Jan Pícha, Daniel Jun
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Preparing a rat brain tissue samples for acetylcholinesterase activity measurement: The MM method [PDF]
Background/Aim: Organophosphorus compounds (OP) bind to acetylcholinesterase (AChE) causing an irreversible inhibition of the enzyme. When doing in vivo studies of OP intoxication, to precisely measure AChE activity in the brain tissue it is necessary to
Marinković Sonja +5 more
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Comparison of pKa values for oxy-enzymase derivatives derived from 3-acetyl and 4-acetyl-3 serotonin by using glass pole [PDF]
The study includes the preparation of four syn and anti oximes derived from mother ketones, namely 3-acetyl and 4-acetyl pyridine by standard method. The structures of these oximes were confirmed by using UV and IR spectra, melting points and specific ...
Adel Azzoz, rawaa Suliaman
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A novel oxime platform, the substituted phenoxyalkyl pyridinium oximes (US patent 9,227,937), was invented at Mississippi State University with an objective of discovering a brain-penetrating antidote to highly potent organophosphate anticholinesterases,
Janice E. Chambers, Edward C. Meek
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Pharmacokinetic Studies on Oximes in Organophosphate Poisoning: A Mini Review [PDF]
Organophosphate (OP) poisoning is one of the most common causes of poisoning in developing countries especially in Southeastern Asia. Poisoning with phosphorus-containing organic chemicals or OP compounds can be managed with antidotes like oximes which ...
Girish Thunga +6 more
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