Results 11 to 20 of about 5,697 (170)

Metal-free sustainable synthesis of oximes and hydrazones from benzyl alcohol and benzylamine [PDF]

open access: yesRSC Advances
Herein, we report a one-pot synthesis of oximes and hydrazones via oxidative coupling of alcohols and amines with hydroxylamine hydrochloride and hydrazine, mediated by N-bromosuccinimide (NBS) and phenyliodine(iii) diacetate (PIDA), respectively.
Rupali B. Devgunde   +3 more
doaj   +2 more sources

Conversion of Natural Aldehydes from Eucalyptus citriodora, Cymbopogon citratus, and Lippia multiflora into Oximes: GC-MS and FT-IR Analysis †

open access: yesMolecules, 2009
Three carbonyl-containing extracts of essential oils from Eucalyptus citriodora (Myrtaceae), Cymbopogon citratus (Gramineae) and Lippia multiflora (Verbenaceae) were used for the preparation of oximes.
Igor W. Ouédraogo   +4 more
doaj   +1 more source

A Comparison of the Therapeutic Efficacy of Conventional and Modern Oximes Against Supralethal Doses of Highly Toxic Organophosphates in Mice

open access: yesActa Medica, 1998
1. The therapeutic efficacy of various oximes (pralidoxime, obidoxime, methoxime, HI-6, HLö-7, BI-6) against supralethal nerve agent poisoning (soman, sarin, cyclosin) in mice was tested. 2. New oxime BI-6, synthesized in our laboratory, is significantly
Jiří Kassa
doaj   +1 more source

Amidoximes and Oximes: Synthesis, Structure, and Their Key Role as NO Donors

open access: yesMolecules, 2019
Nitric oxide (NO) is naturally synthesized in the human body and presents many beneficial biological effects; in particular on the cardiovascular system.
Tanya Sahyoun   +2 more
doaj   +1 more source

A Comparison of the Potency of Newly Developed Oximes (K347, K628) and Currently Available Oximes (Obidoxime, HI-6) to Counteract Acute Neurotoxic Effects of Tabun in Rats

open access: yesActa Medica, 2010
The ability of newly developed oximes (K347, K628) to reduce tabun-induced acute neurotoxic signs and symptoms was compared with currently available oximes (obidoxime, HI-6) using a functional observational battery.
Jiří Kassa   +4 more
doaj   +1 more source

Reactivation Potency of New Group of Acetylcholinesterase Reactivators and Their Comparison with Currently Available Oximes

open access: yesActa Medica, 2006
In this work, in vitro potency of novel serie of monoquaternary pyridinium oximes to reactivate cyclosarin-inhibited acetylcholinesterase (AChE) was tested.
Kamil Kuča, Jan Pícha, Daniel Jun
doaj   +1 more source

Preparing a rat brain tissue samples for acetylcholinesterase activity measurement: The MM method [PDF]

open access: yesScripta Medica, 2021
Background/Aim: Organophosphorus compounds (OP) bind to acetylcholinesterase (AChE) causing an irreversible inhibition of the enzyme. When doing in vivo studies of OP intoxication, to precisely measure AChE activity in the brain tissue it is necessary to
Marinković Sonja   +5 more
doaj   +1 more source

Comparison of pKa values for oxy-enzymase derivatives derived from 3-acetyl and 4-acetyl-3 serotonin by using glass pole [PDF]

open access: yesمجلة التربية والعلم, 2014
The study includes the preparation of four syn and anti oximes derived from mother ketones, namely 3-acetyl and 4-acetyl pyridine by standard method. The structures of these oximes were confirmed by using UV and IR spectra, melting points and specific ...
Adel Azzoz, rawaa Suliaman
doaj   +1 more source

Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX

open access: yesNeurobiology of Disease, 2020
A novel oxime platform, the substituted phenoxyalkyl pyridinium oximes (US patent 9,227,937), was invented at Mississippi State University with an objective of discovering a brain-penetrating antidote to highly potent organophosphate anticholinesterases,
Janice E. Chambers, Edward C. Meek
doaj   +1 more source

Pharmacokinetic Studies on Oximes in Organophosphate Poisoning: A Mini Review [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Organophosphate (OP) poisoning is one of the most common causes of poisoning in developing countries especially in Southeastern Asia. Poisoning with phosphorus-containing organic chemicals or OP compounds can be managed with antidotes like oximes which ...
Girish Thunga   +6 more
doaj  

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